Set7 mediated Gli3 methylation plays a positive role in the activation of Sonic Hedgehog pathway in mammals
about
Lysine methylation of FEN1 by SET7 is essential for its cellular response to replicative stress.Targeting posttranslational modifications of RIOK1 inhibits the progression of colorectal and gastric cancers.LSD1 demethylase and the methyl-binding protein PHF20L1 prevent SET7 methyltransferase-dependent proteolysis of the stem-cell protein Sox2.Hedgehog signalling in the tumourigenesis and metastasis of osteosarcoma, and its potential value in the clinical therapy of osteosarcoma.Methylated DNMT1 and E2F1 are targeted for proteolysis by L3MBTL3 and CRL4DCAF5 ubiquitin ligase.Role of GLI Transcription Factors in Pathogenesis and Their Potential as New Therapeutic Targets
P2860
Set7 mediated Gli3 methylation plays a positive role in the activation of Sonic Hedgehog pathway in mammals
description
2016 nî lūn-bûn
@nan
2016 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2016 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
name
Set7 mediated Gli3 methylation ...... ic Hedgehog pathway in mammals
@ast
Set7 mediated Gli3 methylation ...... ic Hedgehog pathway in mammals
@en
type
label
Set7 mediated Gli3 methylation ...... ic Hedgehog pathway in mammals
@ast
Set7 mediated Gli3 methylation ...... ic Hedgehog pathway in mammals
@en
prefLabel
Set7 mediated Gli3 methylation ...... ic Hedgehog pathway in mammals
@ast
Set7 mediated Gli3 methylation ...... ic Hedgehog pathway in mammals
@en
P2093
P2860
P3181
P356
P1433
P1476
Set7 mediated Gli3 methylation ...... ic Hedgehog pathway in mammals
@en
P2093
Hailong Wu
Steven Y Cheng
P2860
P3181
P356
10.7554/ELIFE.15690
P407
P577
2016-05-05T00:00:00Z