Hedgehog-regulated processing of Gli3 produces an anterior/posterior repressor gradient in the developing vertebrate limb
about
Gli2 and Gli3 localize to cilia and require the intraflagellar transport protein polaris for processing and functionThe sonic hedgehog-patched-gli pathway in human development and diseasePhysical and functional interactions between Zic and Gli proteinsEvidence for the direct involvement of {beta}TrCP in Gli3 protein processingTULP3 bridges the IFT-A complex and membrane phosphoinositides to promote trafficking of G protein-coupled receptors into primary ciliaMediator modulates Gli3-dependent Sonic hedgehog signalingA potential role of alternative splicing in the regulation of the transcriptional activity of human GLI2 in gonadal tissues.Ski is involved in transcriptional regulation by the repressor and full-length forms of Gli3The antagonistic action of B56-containing protein phosphatase 2As and casein kinase 2 controls the phosphorylation and Gli turnover function of Daz interacting protein 1Dual function of UNC-51-like kinase 3 (Ulk3) in the Sonic hedgehog signaling pathwayMice deficient in the fused homolog do not exhibit phenotypes indicative of perturbed hedgehog signaling during embryonic developmentSuppressor of Fused represses Gli-mediated transcription by recruiting the SAP18-mSin3 corepressor complexGli proteins and the control of spinal-cord patterningA gradient of Gli activity mediates graded Sonic Hedgehog signaling in the neural tubeThe output of Hedgehog signaling is controlled by the dynamic association between Suppressor of Fused and the Gli proteinsDisruption of Mks1 localization to the mother centriole causes cilia defects and developmental malformations in Meckel-Gruber syndromeA small molecule that binds Hedgehog and blocks its signaling in human cellsGLI2-specific transcriptional activation of the bone morphogenetic protein/activin antagonist follistatin in human epidermal cellsEstablishing and interpreting graded Sonic Hedgehog signaling during vertebrate neural tube patterning: the role of negative feedbackMutual genetic antagonism involving GLI3 and dHAND prepatterns the vertebrate limb bud mesenchyme prior to SHH signalingDorsal-ventral patterning of the spinal cord requires Gli3 transcriptional repressor activityMicroRNAs in liver fibrosis: Focusing on the interaction with hedgehog signalingThe cilia-regulated proteasome and its role in the development of ciliopathies and cancerThe Role of Hedgehog Signaling in Tumor Induced Bone DiseaseCooperative integration between HEDGEHOG-GLI signalling and other oncogenic pathways: implications for cancer therapyHedgehog signaling and maintenance of homeostasis in the intestinal epitheliumPrimary cilium and sonic hedgehog signaling during neural tube patterning: role of GPCRs and second messengersReview of the molecular development of the thumb: digit primeraDecoding the phosphorylation code in Hedgehog signal transductionContext-dependent signal integration by the GLI code: the oncogenic load, pathways, modifiers and implications for cancer therapyC2cd3 is required for cilia formation and Hedgehog signaling in mouse.The Hedgehog signalling pathway in bone formationDisruption of a ciliary B9 protein complex causes Meckel syndromeCentrosomal protein DZIP1 regulates Hedgehog signaling by promoting cytoplasmic retention of transcription factor GLI3 and affecting ciliogenesisSpecification of ventral neuron types is mediated by an antagonistic interaction between Shh and Gli3Hox genes regulate digit patterning by controlling the wavelength of a Turing-type mechanismCilia and developmental signalingPhosphorylation regulates OLIG2 cofactor choice and the motor neuron-oligodendrocyte fate switchDistinct roles of Hand2 in initiating polarity and posterior Shh expression during the onset of mouse limb bud developmentIntraflagellar transport protein 122 antagonizes Sonic Hedgehog signaling and controls ciliary localization of pathway components
P2860
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P2860
Hedgehog-regulated processing of Gli3 produces an anterior/posterior repressor gradient in the developing vertebrate limb
description
2000 nî lūn-bûn
@nan
2000 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Hedgehog-regulated processing ...... the developing vertebrate limb
@ast
Hedgehog-regulated processing ...... the developing vertebrate limb
@en
Hedgehog-regulated processing ...... the developing vertebrate limb
@en-gb
Hedgehog-regulated processing ...... the developing vertebrate limb
@nl
type
label
Hedgehog-regulated processing ...... the developing vertebrate limb
@ast
Hedgehog-regulated processing ...... the developing vertebrate limb
@en
Hedgehog-regulated processing ...... the developing vertebrate limb
@en-gb
Hedgehog-regulated processing ...... the developing vertebrate limb
@nl
prefLabel
Hedgehog-regulated processing ...... the developing vertebrate limb
@ast
Hedgehog-regulated processing ...... the developing vertebrate limb
@en
Hedgehog-regulated processing ...... the developing vertebrate limb
@en-gb
Hedgehog-regulated processing ...... the developing vertebrate limb
@nl
P2093
P3181
P1433
P1476
Hedgehog-regulated processing ...... the developing vertebrate limb
@en
P2093
P304
P3181
P356
10.1016/S0092-8674(00)80678-9
P407
P577
2000-02-18T00:00:00Z