about
The foxa2 gene controls the birth and spontaneous degeneration of dopamine neurons in old ageAbsence of Ret signaling in mice causes progressive and late degeneration of the nigrostriatal systemDJ-1 is a redox-dependent molecular chaperone that inhibits alpha-synuclein aggregate formationBrain region specific mitophagy capacity could contribute to selective neuronal vulnerability in Parkinson's diseaseBiomedical and clinical promises of human pluripotent stem cells for neurological disordersSulforaphane as a potential protective phytochemical against neurodegenerative diseasesTransgenic rodent models of Parkinson’s diseaseAnticholinergics for neuroleptic-induced parkinsonism and tardive dyskinesiaRelationships between the sequence of alpha-synuclein and its membrane affinity, fibrillization propensity, and yeast toxicityMAP1B rescues LRRK2 mutant-mediated cytotoxicityRac1 protein rescues neurite retraction caused by G2019S leucine-rich repeat kinase 2 (LRRK2)Leucine-rich repeat kinase 2 (LRRK2) interacts with parkin, and mutant LRRK2 induces neuronal degeneration.Cytosolic cleaved PINK1 represses Parkin translocation to mitochondria and mitophagyATF4 protects against neuronal death in cellular Parkinson's disease models by maintaining levels of parkinEvidence that alpha-synuclein does not inhibit phospholipase DThiol peroxidases ameliorate LRRK2 mutant-induced mitochondrial and dopaminergic neuronal degeneration in DrosophilaThe Parkinson disease protein leucine-rich repeat kinase 2 transduces death signals via Fas-associated protein with death domain and caspase-8 in a cellular model of neurodegenerationMutations in LRRK2 increase phosphorylation of peroxiredoxin 3 exacerbating oxidative stress-induced neuronal deathDopamine covalently modifies and functionally inactivates parkinHigh-resolution whole-genome association study of Parkinson disease.Disrupted autophagy leads to dopaminergic axon and dendrite degeneration and promotes presynaptic accumulation of α-synuclein and LRRK2 in the brainInhibition of rho kinase enhances survival of dopaminergic neurons and attenuates axonal loss in a mouse model of Parkinson's diseaseGhrelin promotes and protects nigrostriatal dopamine function via a UCP2-dependent mitochondrial mechanismGlial cells as intrinsic components of non-cell-autonomous neurodegenerative diseaseSimvastatin inhibits the activation of p21ras and prevents the loss of dopaminergic neurons in a mouse model of Parkinson's diseaseOxidative stress, mitochondrial dysfunction, and agingDopamine and inhibitory action control: evidence from spontaneous eye blink rates.Targeting neural precursors in the adult brain rescues injured dopamine neuronsProtein aggregation in the brain: the molecular basis for Alzheimer's and Parkinson's diseasesIntrabody and Parkinson's diseaseInclusion formation and neuronal cell death through neuron-to-neuron transmission of alpha-synucleinAlpha-synuclein blocks ER-Golgi traffic and Rab1 rescues neuron loss in Parkinson's modelsMolecules that cause or prevent Parkinson's diseaseSensitivity to oxidative stress in DJ-1-deficient dopamine neurons: an ES- derived cell model of primary ParkinsonismDopamine-independent locomotor actions of amphetamines in a novel acute mouse model of Parkinson disease.Exclusion of PINK1 as candidate gene for the late-onset form of Parkinson's disease in two European populations.Parkinson-like syndrome induced by continuous MPTP infusion: convergent roles of the ubiquitin-proteasome system and alpha-synuclein.Prothrombin Kringle-2: A Potential Inflammatory Pathogen in the Parkinsonian Dopaminergic SystemHuman Stem Cell-Derived Astrocytes: Specification and Relevance for Neurological DisordersPrion diseases: immunotargets and therapy
P2860
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P2860
description
2003 nî lūn-bûn
@nan
2003 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Parkinson's disease: mechanisms and models
@ast
Parkinson's disease: mechanisms and models
@en
type
label
Parkinson's disease: mechanisms and models
@ast
Parkinson's disease: mechanisms and models
@en
prefLabel
Parkinson's disease: mechanisms and models
@ast
Parkinson's disease: mechanisms and models
@en
P3181
P1433
P1476
Parkinson's disease: mechanisms and models
@en
P2093
P304
P3181
P356
10.1016/S0896-6273(03)00568-3
P407
P577
2003-09-11T00:00:00Z