TGF-beta signaling in tumor suppression and cancer progression
about
Lack of transforming growth factor-β signaling promotes collective cancer cell invasion through tumor-stromal crosstalk.Induction of pulmonary fibrosis by cerium oxide nanoparticlesGPR56, an atypical G protein-coupled receptor, binds tissue transglutaminase, TG2, and inhibits melanoma tumor growth and metastasisCholesterol suppresses cellular TGF-beta responsiveness: implications in atherogenesisTGF-β signalling is mediated by two autonomously functioning TβRI:TβRII pairsNovel RING E3 ubiquitin ligases in breast cancerNodal enhances the activity of FoxO3a and its synergistic interaction with Smads to regulate cyclin G2 transcription in ovarian cancer cellsIdentification of BMP and activin membrane-bound inhibitor (BAMBI), an inhibitor of transforming growth factor-beta signaling, as a target of the beta-catenin pathway in colorectal tumor cellsTransforming growth factor {beta} (TGF-{beta})-Smad target gene protein tyrosine phosphatase receptor type kappa is required for TGF-{beta} functionSmad7 antagonizes transforming growth factor beta signaling in the nucleus by interfering with functional Smad-DNA complex formationEndogenous TGF-beta signaling suppresses maturation of osteoblastic mesenchymal cellsThe T-box transcription factor eomesodermin controls CD8 T cell activity and lymph node metastasis in human colorectal cancerING2 as a novel mediator of transforming growth factor-beta-dependent responses in epithelial cellsTransforming growth factor beta engages TACE and ErbB3 to activate phosphatidylinositol-3 kinase/Akt in ErbB2-overexpressing breast cancer and desensitizes cells to trastuzumabEngagement of I-branching {beta}-1, 6-N-acetylglucosaminyltransferase 2 in breast cancer metastasis and TGF-{beta} signalingAntibody blockade of the Cripto CFC domain suppresses tumor cell growth in vivoCytoplasmic SnoN in normal tissues and nonmalignant cells antagonizes TGF-beta signaling by sequestration of the Smad proteinsTransforming growth factor-beta1, transforming growth factor-beta2, and transforming growth factor-beta3 enhance ovarian cancer metastatic potential by inducing a Smad3-dependent epithelial-to-mesenchymal transitionIdentification of PCTA, a TGIF antagonist that promotes PML function in TGF-beta signalling15-Hydroxyprostaglandin dehydrogenase, a COX-2 oncogene antagonist, is a TGF-beta-induced suppressor of human gastrointestinal cancersUnbiased screening for transcriptional targets of ZKSCAN3 identifies integrin beta 4 and vascular endothelial growth factor as downstream targetsPrognostic significance of BMP and activin membrane-bound inhibitor in colorectal cancerRequirement for the SnoN oncoprotein in transforming growth factor beta-induced oncogenic transformation of fibroblast cells.Breast cancer bone metastasis mediated by the Smad tumor suppressor pathwayTransforming growth factor beta induces rosettes of podosomes in primary aortic endothelial cells.Autocrine PDGFR signaling promotes mammary cancer metastasisStromal effects on mammary gland development and breast cancerSmad7 induces hepatic metastasis in colorectal cancerThe basics of epithelial-mesenchymal transitionDisruption of the gene encoding the latent transforming growth factor-beta binding protein 4 (LTBP-4) causes abnormal lung development, cardiomyopathy, and colorectal cancerInhibition of transforming growth factor-beta1-induced signaling and epithelial-to-mesenchymal transition by the Smad-binding peptide aptamer Trx-SARAGADD34-PP1c recruited by Smad7 dephosphorylates TGFbeta type I receptorTransforming growth factor beta signaling impairs Neu-induced mammary tumorigenesis while promoting pulmonary metastasisHigh-level inducible Smad4-reexpression in the cervical cancer cell line C4-II is associated with a gene expression profile that predicts a preferential role of Smad4 in extracellular matrix compositionIntegrin alphavbeta8-mediated activation of transforming growth factor-beta inhibits human airway epithelial proliferation in intact bronchial tissueIonizing radiation induces heritable disruption of epithelial cell interactionsConstitutive activation of the Ras-Raf signaling pathway in metastatic melanoma is associated with poor prognosisGenome-wide microarray analysis of TGFbeta signaling in the Drosophila brainInterfering with TGFbeta-induced Smad3 nuclear accumulation differentially affects TGFbeta-dependent gene expressionTransforming growth factor-beta induces Cdk2 relocalization to the cytoplasm coincident with dephosphorylation of retinoblastoma tumor suppressor protein
P2860
Q22000749-AF59FB76-97F9-4F3C-965B-41D62FD25266Q23914456-4D3BEF4D-4CEE-45A4-B0F8-B1C18AFD2260Q24292757-463C6FE7-7D72-4B73-89E6-ABC90CB326D1Q24294300-94EB5ED2-BE6B-4D0E-BCBB-1DD73DA21723Q24297719-E5535A02-496C-4728-BD2F-D45918392615Q24300517-939FFCF5-D1DE-45C9-9088-4CD37DC2089DQ24300910-4F13F9B5-8BCE-4C52-8492-08DBB19D3FEEQ24301259-AB1B9043-5764-4375-916F-1B2BCA4A4AB1Q24302428-553B8C89-5F5F-45B2-960F-588663BC5A29Q24302554-9E584AFC-61C9-456F-98B7-FA32C08801B1Q24306652-00D57073-A32B-4903-80F2-E1969BB63A41Q24310157-D38742B9-4695-403A-9A50-1D23F146152DQ24310196-4BFA2F21-B9CB-464B-BF49-0AE82C5CF3F2Q24313194-92ED8D8E-D055-41FC-B648-23D88E2BBAE9Q24313363-081B3CE3-CB92-40DA-8653-BB4D7EA7C270Q24316195-D58F9C11-2CBD-42B7-B291-86FB0BBAC842Q24316283-391A8D77-5C0C-4EA9-9812-98CEB1EA3F82Q24316645-A0873674-73F8-49AD-A61F-E22B579503B9Q24317578-72C14080-C9AF-4CCF-B9A0-1A01971DBA83Q24318523-D497B0CA-A950-4A3D-8DAB-0B8D70E10EECQ24336689-B581ED7A-456A-4B47-97AF-D86E607FCC87Q24337061-53685ADC-7927-4075-AC8C-B6D6AB3771DBQ24534996-9C6259C1-ADAA-4FD5-8B61-0612806DEEA5Q24536061-70970034-64C8-429B-B9AF-6BC8C6F4F356Q24544223-108DEEE2-C5C5-48ED-8CCF-551DF9FFCD82Q24545375-092EDA73-BA0C-43BF-9FC5-A7A57C5160B6Q24645558-6C870CB3-FBBD-4FC9-BD26-9F976D3B333BQ24649660-F369E66E-5EB8-41BB-8E11-A4A2B8FDA813Q24652992-413E79E7-2FDF-4B2C-8717-D6C9ABE7797DQ24671034-3517D339-4C42-4754-B4A3-DBEE11B46F55Q24671742-073AFE36-FBBC-4779-A668-14EB0F9C4EE5Q24676599-65FE3F42-102C-4091-9FBB-88EF56653C34Q24679619-FBBE1870-FB8A-463F-A362-A1CF9E5B3854Q24683692-FAF67B32-0FE4-48FA-94E4-94F0C9E98A04Q24685525-A3CEE15F-AD6C-4AAD-8AF7-4F966883CD8EQ24685810-168F3274-B9CF-44BB-A8BE-9063B0848272Q24791830-D37530E9-C9A2-4642-8598-65D511A78BA4Q24792567-E0E8D7E1-6E00-40DB-B594-420060B79C43Q24793548-32FB0B6D-56EA-4777-BBCE-77E94B39734CQ24794459-B88E8989-F17B-4451-A174-4FE9E9539ACF
P2860
TGF-beta signaling in tumor suppression and cancer progression
description
2001 nî lūn-bûn
@nan
2001 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
TGF-beta signaling in tumor suppression and cancer progression
@ast
TGF-beta signaling in tumor suppression and cancer progression
@en
type
label
TGF-beta signaling in tumor suppression and cancer progression
@ast
TGF-beta signaling in tumor suppression and cancer progression
@en
prefLabel
TGF-beta signaling in tumor suppression and cancer progression
@ast
TGF-beta signaling in tumor suppression and cancer progression
@en
P2093
P3181
P356
P1433
P1476
TGF-beta signaling in tumor suppression and cancer progression
@en
P2093
P2888
P304
P3181
P356
10.1038/NG1001-117
P407
P577
2001-10-01T00:00:00Z
P6179
1010058562