Adaptor protein 3BP2 is a potential ligand of Src homology 2 and 3 domains of Lyn protein-tyrosine kinase.
about
Cherubism: best clinical practiceAbl-SH3 binding protein 2, 3BP2, interacts with CIN85 and HIP-55Negative regulation of Lyn protein-tyrosine kinase by c-Cbl ubiquitin-protein ligase in Fc epsilon RI-mediated mast cell activationEtanercept administration to neonatal SH3BP2 knock-in cherubism mice prevents TNF-α-induced inflammation and bone loss.SH3BP2 cherubism mutation potentiates TNF-α-induced osteoclastogenesis via NFATc1 and TNF-α-mediated inflammatory bone loss.HCV NS5A protein containing potential ligands for both Src homology 2 and 3 domains enhances autophosphorylation of Src family kinase Fyn in B cells.The adaptor 3BP2 is required for early and late events in FcεRI signaling in human mast cells.Association of 3BP2 with SHP-1 regulates SHP-1-mediated production of TNF-α in RBL-2H3 cells.3BP2-deficient mice are osteoporotic with impaired osteoblast and osteoclast functionsTyrosine phosphorylation of 3BP2 regulates B cell receptor-mediated activation of NFATAdapters in the organization of mast cell signaling.The role of SH3BP2 in the pathophysiology of cherubism.Syk and pTyr'd: Signaling through the B cell antigen receptor3BP2 deficiency impairs the response of B cells, but not T cells, to antigen receptor ligation.Decreased SH3BP2 inhibits osteoclast differentiation and functionSyk-dependent tyrosine phosphorylation of 3BP2 is required for optimal FcRγ-mediated phagocytosis and chemokine expression in U937 cells.Enhanced TLR-MYD88 signaling stimulates autoinflammation in SH3BP2 cherubism mice and defines the etiology of cherubism.SH3BP2 is a critical regulator of macrophage and osteoclast response to M-CSF and RANKL stimulation.Selective inhibition of Fcepsilon RI-mediated mast cell activation by a truncated variant of Cbl-b related to the rat model of type 1 diabetes mellitus.SHP-1 dephosphorylates 3BP2 and potentially downregulates 3BP2-mediated T cell antigen receptor signalingMolecular and cellular characterizations of human cherubism: disease aggressiveness depends on osteoclast differentiation
P2860
Q21202854-03EC8BAC-D79B-4BF6-926E-2C750DF59BE6Q24297487-C33799A4-8089-431F-BA74-83DEDA9E441CQ28577409-212C165B-C8E9-43BB-90CA-C6A3483D38FDQ30009390-84681EB1-B101-454E-85F2-2E1713F153C9Q30009398-9B516D90-F100-40B7-BC18-88FD8EB8F7EAQ30009991-2D47DA37-0818-40D5-B2A4-823732BD2B1DQ30010031-A9A3B380-6A9A-490C-9772-6743ECC9BC81Q30010210-1262DFEF-FDBC-41E0-ACB5-CC01C138BDB9Q30010273-32A0CC0D-208A-4754-AB58-E584332D03FAQ30157087-4BBF63C8-6D78-418C-B220-7458A0A50CCDQ34476441-8A60A43B-7771-4723-8ABD-2D6B7E3A709CQ35987370-953788BC-C5AB-4578-B822-CA997795923FQ37237143-8508B391-F1CF-4AC3-BD3E-F4C340B7447FQ38406110-79F7AF29-96BC-4CD4-ACC0-8AA001E5DE50Q39568444-22614B64-49C3-4195-805D-C2FD5A93E31FQ41125333-0B1271B1-C497-4885-A4BB-820C28382B89Q42918583-78D8360F-CF6E-4814-8B38-0E068FCA3EBCQ43181076-E8427C02-B789-4424-899A-DD684566F80FQ53667349-7BA6AC92-0C42-4148-9EE6-9DF8B59CC1A5Q57374325-7BB32888-04D0-45C6-B619-3BCF64296A9EQ58711955-54EF8BBE-D398-438E-A9DE-9A85DA65C5B6
P2860
Adaptor protein 3BP2 is a potential ligand of Src homology 2 and 3 domains of Lyn protein-tyrosine kinase.
description
2003 nî lūn-bûn
@nan
2003 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Adaptor protein 3BP2 is a pote ...... f Lyn protein-tyrosine kinase.
@ast
Adaptor protein 3BP2 is a pote ...... f Lyn protein-tyrosine kinase.
@en
type
label
Adaptor protein 3BP2 is a pote ...... f Lyn protein-tyrosine kinase.
@ast
Adaptor protein 3BP2 is a pote ...... f Lyn protein-tyrosine kinase.
@en
prefLabel
Adaptor protein 3BP2 is a pote ...... f Lyn protein-tyrosine kinase.
@ast
Adaptor protein 3BP2 is a pote ...... f Lyn protein-tyrosine kinase.
@en
P2093
P2860
P356
P1476
Adaptor protein 3BP2 is a pote ...... f Lyn protein-tyrosine kinase.
@en
P2093
Hirohei Yamamura
Keiko Kawauchi-Kamata
Koichiro Maeno
S M Shahjahan Miah
Shinkou Kyo
Xiujuan Qu
Yuhong Shi
P2860
P304
24912-24920
P356
10.1074/JBC.M301201200
P407
P50
P577
2003-04-22T00:00:00Z