about
The replicative senescent mesenchymal stem / stromal cells defect in DNA damage response and anti-oxidative capacity.Liver Cancer Initiation Requires p53 Inhibition by CD44-Enhanced Growth Factor SignalingKinase inhibitor library screening identifies synergistic drug combinations effective in sensitive and resistant melanoma cellsLoss of NFBD1/MDC1 disrupts homologous recombination repair and sensitizes nasopharyngeal carcinoma cells to PARP inhibitorsGenotoxic stress causes the accumulation of DNA-dependent protein kinase catalytic subunit phosphorylated at serine 2056 at nuclear speckles and alters pre-mRNA alternative splicingPlatinum Resistance in Ovarian Cancer: Role of DNA RepairPARPs in genome stability and signal transduction: implications for cancer therapyThe influence of retinoic acid-induced differentiation on the radiation response of male germline stem cellsP-TEFb Activation by RBM7 Shapes a Pro-survival Transcriptional Response to Genotoxic StressKnockdown of KLF5 promotes cisplatin-induced cell apoptosis via regulating DNA damage checkpoint proteins in non-small cell lung cancerViral Chromosome Conformation Capture (V3C) Assays for Identifying Trans-interaction Sites between Lytic Viruses and the Cellular GenomeDynamics of Replication Fork Progression Following Helicase-Polymerase Uncoupling in EukaryotesBovine Embryo-Secreted microRNA-30c Is a Potential Non-invasive Biomarker for Hampered Preimplantation Developmental CompetencePrecise Gene Editing Preserves Hematopoietic Stem Cell Function following Transient p53-Mediated DNA Damage ResponseCardiac Nuclear High-Mobility Group Box 1 Ameliorates Pathological Cardiac Hypertrophy by Inhibiting DNA Damage ResponseAge-related dysfunction of the DNA damage response in intestinal stem cellsThe Emerging Roles of TERRA in Telomere Maintenance and Genome StabilityEpitranscriptomic m6A modification in the stem cell field and its effects on cell death and survivalThe Tumor Immune Contexture of Prostate CancerNew combinatorial strategies to improve the PARP inhibitors efficacy in the urothelial bladder Cancer treatmentA Novel Diagnostic Method for Thyroid Follicular Tumors Based on Immunofluorescence Analysis of p53-Binding Protein 1 Expression: Detection of Genomic InstabilityMathematical modelling of core regulatory mechanism in p53 protein that activates apoptotic switchInterplay between heat shock proteins, inflammation and cancer: a potential cancer therapeutic targetWomen's cancers: how the discovery of BRCA genes is driving current concepts of cancer biology and therapeuticsPhosphoglycolate has profound metabolic effects but most likely no role in a metabolic DNA response in cancer cell linesGermline Risk Contribution to Genomic Instability in Multiple MyelomaMRN (MRE11-RAD50-NBS1) Complex in Human Cancer and Prognostic Implications in Colorectal Canceras a Model to Study the Multiple Phenotypes, Related to Genome Stability of the Fragile-X SyndromePreferential digestion of PCNA-ubiquitin and p53-ubiquitin linkages by USP7 to remove polyubiquitin chains from substratesMutant huntingtin impairs PNKP and ATXN3, disrupting DNA repair and transcriptionBiphasic Functional Interaction between the Adenovirus E4orf4 Protein and DNA-PKLocalization of the kinase Ataxia Telangiectasia Mutated to Adenovirus E4 mutant DNA replication centers is important for its inhibitory effect on viral DNA accumulationGenetic interaction between DNA repair factors PAXX, XLF, XRCC4 and DNA-PKcs in human cellsDNA Damage Response and Repair Pathway Alteration and Its Association with Tumor Mutation Burden and Platinum-Based Chemotherapy in Small Cell Lung CancerNEK5 interacts with topoisomerase IIβ and is involved in the DNA damage response induced by etoposideDNA damage response after ionizing radiation exposure in skin keratinocytes derived from human induced pluripotent stem cellsActivation of Tel1 kinase requires Rad50 ATPase and long nucleosome-free DNA, but no DNA endsNOD2 agonist murabutide alleviates radiation-induced injury through DNA damage response pathway mediated by ATRThe deubiquitinase OTUD5 regulates Ku80 stability and non-homologous end joiningSWI/SNF: Complex complexes in genome stability and cancer
P921
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P921
description
This is the first pathway out ...... divides furthermore into t...
@en
name
DNA Damage Response
@en
type
label
DNA Damage Response
@en
prefLabel
DNA Damage Response
@en
P2093
P2860
P50
P527
P1476
DNA Damage Response
@en
P2093
Alexander Pico
Christine Chichester
Daniela Digles
Egon Willighagen
Jonas Hummel
Kristina Hanspers
Martijn Van Iersel
Martina Kutmon
Ryan Miller