Causal effects of body mass index on cardiometabolic traits and events: a Mendelian randomization analysis. - sprookjes - yvandenbroek - TriplyDB

Causal effects of body mass index on cardiometabolic traits and events: a Mendelian randomization analysis.

Causal effects of body mass index on cardiometabolic traits and events: a Mendelian randomization analysis.

http://www.wikidata.org/entity/Q30411394

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MR-PheWAS: hypothesis prioritization among potential causal effects of body mass index on many outcomes, using Mendelian randomization Association Between Interleukin-6 -572 C>G and -174 G>C Polymorphisms and Hypertension: A Meta-analysis of Case-control Studies Are there genetic paths common to obesity, cardiovascular disease outcomes, and cardiovascular risk factors?Mendelian Randomization and Type 2 Diabetes Trans-ethnic genome-wide association studies: advantages and challenges of mapping in diverse populations.Metabolic signatures of adiposity in young adults: Mendelian randomization analysis and effects of weight change Body mass index: Has epidemiology started to break down causal contributions to health and disease?Causal Associations of Adiposity and Body Fat Distribution with Coronary Heart Disease, Stroke Subtypes and Type 2 Diabetes: A Mendelian Randomization Analysis.Association of lactase persistence genotype with milk consumption, obesity and blood pressure: a Mendelian randomization study in the 1982 Pelotas (Brazil) Birth Cohort, with a systematic review and meta-analysis Defining a Contemporary Ischemic Heart Disease Genetic Risk Profile Using Historical Data.Mendelian randomization analysis of a time-varying exposure for binary disease outcomes using functional data analysis methods.Healthy obesity and risk of accelerated functional decline and disability A dysglycaemic effect of statins in diabetes: relevance to clinical practice?Potential Impact of Time Trend of Life-Style Factors on Cardiovascular Disease Burden in China.HMG-coenzyme A reductase inhibition, type 2 diabetes, and bodyweight: evidence from genetic analysis and randomised trials.Evaluation of an association between plasma total homocysteine and schizophrenia by a Mendelian randomization analysis.Adiposity as a cause of cardiovascular disease: a Mendelian randomization study.Genetic and environmental determinants of population variation in interleukin-6, its soluble receptor and C-reactive protein: insights from identical and fraternal twins.Blood pressure in relation to general and central adiposity among 500 000 adult Chinese men and women.Body-mass index and risk of advanced chronic kidney disease: Prospective analyses from a primary care cohort of 1.4 million adults in England.Genetic Evidence for a Causal Role of Obesity in Diabetic Kidney Disease.A genetic stochastic process model for genome-wide joint analysis of biomarker dynamics and disease susceptibility with longitudinal data.Type 2 Diabetes Genetic Predisposition, Obesity, and All-Cause Mortality Risk in the U.S.: A Multiethnic Analysis.Lean body mass and risk of incident atrial fibrillation in post-menopausal women.Accuracy of Body Mass Index Cutoffs for Classifying Obesity in Chilean Children and Adolescents Estimating Marginal Healthcare Costs Using Genetic Variants as Instrumental Variables: Mendelian Randomization in Economic Evaluation Selecting instruments for Mendelian randomization in the wake of genome-wide association studies.Detection and interpretation of shared genetic influences on 42 human traits.Adiposity and Blood Pressure in 110 000 Mexican Adults.Impact of metabolic disorders on the relation between overweight/obesity and incident myocardial infarction and ischaemic stroke in fertile women: a nationwide cohort study.Genetic risk factors and Mendelian randomization in cardiovascular disease.Is Insulin Resistance a Feature of or a Primary Risk Factor for Cardiovascular Disease?Association of Body Mass Index With Cardiometabolic Disease in the UK Biobank: A Mendelian Randomization Study.Type 2 diabetes, glucose, insulin, BMI, and ischemic stroke subtypes: Mendelian randomization study.Genetic support for the causal role of insulin in coronary heart disease.Cardiometabolic Abnormalities Among Normal-Weight Persons From Five Racial/Ethnic Groups in the United States: A Cross-sectional Analysis of Two Cohort Studies.Adult height, coronary heart disease and stroke: a multi-locus Mendelian randomization meta-analysis.The role of glycaemic and lipid risk factors in mediating the effect of BMI on coronary heart disease: a two-step, two-sample Mendelian randomisation study.Metabolic signatures of birthweight in 18 288 adolescents and adults.BMI as a Modifiable Risk Factor for Type 2 Diabetes: Refining and Understanding Causal Estimates Using Mendelian Randomization.

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P2860

Causal effects of body mass index on cardiometabolic traits and events: a Mendelian randomization analysis.

http://www.wikidata.org/entity/Q30411394

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2014 nî lūn-bûn

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2014 թուականի Յունուարին հրատարակուած գիտական յօդուած

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2014年の論文

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P2860

Potential etiologic and functional implications of genome-wide association loci for human diseases and traits

Obesity and Cardiovascular Disease: Pathophysiology, Evaluation, and Effect of Weight Loss

Body-Mass Index and Mortality among 1.46 Million White Adults

Reduction in the Incidence of Type 2 Diabetes with Lifestyle Intervention or Metformin

Common variation in the FTO gene alters diabetes-related metabolic traits to the extent expected given its effect on BMI

Blood pressure loci identified with a gene-centric array

10-year follow-up of diabetes incidence and weight loss in the Diabetes Prevention Program Outcomes Study

Body-mass index and cause-specific mortality in 900 000 adults: collaborative analyses of 57 prospective studies

Use of blood pressure lowering drugs in the prevention of cardiovascular disease: meta-analysis of 147 randomised trials in the context of expectations from prospective epidemiological studies

Cancer incidence and mortality in relation to body mass index in the Million Women Study: cohort study

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Garret A. FitzGerald

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