A novel PTEN/mutant p53/c-Myc/Bcl-XL axis mediates context-dependent oncogenic effects of PTEN with implications for cancer prognosis and therapy

A novel PTEN/mutant p53/c-Myc/Bcl-XL axis mediates context-dependent oncogenic effects of PTEN with implications for cancer prognosis and therapy

Item
http://www.wikidata.org/entity/Q30417988
Mutant p53 Drives Cancer by Subverting Multiple Tumor Suppression PathwaysmicroRNA-148a is a prognostic oncomiR that targets MIG6 and BIM to regulate EGFR and apoptosis in glioblastoma.Global Conservation of Protein Status between Cell Lines and XenograftsCancer subclonal genetic architecture as a key to personalized medicine.Mutant p53 in cancer: new functions and therapeutic opportunities.p53 regulates cytoskeleton remodeling to suppress tumor progression.Genetic biomarkers of drug response for small-molecule therapeutics targeting the RTK/Ras/PI3K, p53 or Rb pathway in glioblastoma.A high definition look at the NF-Y regulome reveals genome-wide associations with selected transcription factors.Oncogenic Mutant p53 Gain of Function Nourishes the Vicious Cycle of Tumor Development and Cancer Stem-Cell Formation.Pnck overexpression in HER-2 gene-amplified breast cancer causes Trastuzumab resistance through a paradoxical PTEN-mediated process.p53 is active in murine stem cells and alters the transcriptome in a manner that is reminiscent of mutant p53.Mutant p53 partners in crime.Li-Fraumeni Syndrome Disease Model: A Platform to Develop Precision Cancer Therapy Targeting Oncogenic p53.The BET Bromodomain Inhibitor JQ1 Suppresses Chondrosarcoma Cell Growth via Regulation of YAP/p21/c-Myc Signaling.The p53 Pathway in Glioblastoma
P2860

A novel PTEN/mutant p53/c-Myc/Bcl-XL axis mediates context-dependent oncogenic effects of PTEN with implications for cancer prognosis and therapy

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http://www.wikidata.org/entity/Q30417988
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2013 nî lūn-bûn
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2013 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2013年の論文
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2013年学术文章
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2013年学术文章
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2013年学术文章
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2013年学术文章
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2013年学术文章
@zh-sg
2013年學術文章
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name
A novel PTEN/mutant p53/c-Myc/ ...... r cancer prognosis and therapy
@ast
A novel PTEN/mutant p53/c-Myc/ ...... r cancer prognosis and therapy
@en
type
label
A novel PTEN/mutant p53/c-Myc/ ...... r cancer prognosis and therapy
@ast
A novel PTEN/mutant p53/c-Myc/ ...... r cancer prognosis and therapy
@en
prefLabel
A novel PTEN/mutant p53/c-Myc/ ...... r cancer prognosis and therapy
@ast
A novel PTEN/mutant p53/c-Myc/ ...... r cancer prognosis and therapy
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P433
P478
P50
P577
P5875
P698
P932
P356
P1433
P1476
A novel PTEN/mutant p53/c-Myc/ ...... r cancer prognosis and therapy
@en
P2093
P2860
P304
P31
P356
P433
P478
P50
P577
P5875
P698
P932