Isolation, biology and chemistry of the disorazoles: new anti-cancer macrodiolides
about
Pretubulysin: from hypothetical biosynthetic intermediate to potential lead in tumor therapyTotal synthesis of (-)-CP2-disorazole C1.Screening of small molecules affecting mammalian P-body assembly uncovers links with diverse intracellular processes and organelle physiology.Identification of myxobacteria-derived HIV inhibitors by a high-throughput two-step infectivity assay.Genetic engineering and heterologous expression of the disorazol biosynthetic gene cluster via Red/ET recombineering.Bis-cyclopropane analog of disorazole C1 is a microtubule-destabilizing agent active in ABCB1-overexpressing human colon cancer cells.Synthesis of heterocyclic triads by Pd-catalyzed cross-couplings and evaluation of their cell-specific toxicity profile.Microtubules as antifungal and antiparasitic drug targets.The synthesis of novel disorazoles.Self-Assembly of Disorazole C1 through a One-Pot Alkyne Metathesis Homodimerization Strategy.Self-Assembly of Disorazole C1 through a One-Pot Alkyne Metathesis Homodimerization StrategyCatalytic Z-selective cross-metathesis in complex molecule synthesis: a convergent stereoselective route to disorazole C1.
P2860
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P2860
Isolation, biology and chemistry of the disorazoles: new anti-cancer macrodiolides
description
2009 nî lūn-bûn
@nan
2009 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի մարտին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Isolation, biology and chemistry of the disorazoles: new anti-cancer macrodiolides
@ast
Isolation, biology and chemistry of the disorazoles: new anti-cancer macrodiolides
@en
type
label
Isolation, biology and chemistry of the disorazoles: new anti-cancer macrodiolides
@ast
Isolation, biology and chemistry of the disorazoles: new anti-cancer macrodiolides
@en
prefLabel
Isolation, biology and chemistry of the disorazoles: new anti-cancer macrodiolides
@ast
Isolation, biology and chemistry of the disorazoles: new anti-cancer macrodiolides
@en
P2860
P356
P1476
Isolation, biology and chemistry of the disorazoles: new anti-cancer macrodiolides
@en
P2093
Chad D Hopkins
P2860
P304
P356
10.1039/B813799B
P50
P577
2009-03-11T00:00:00Z