Mechanisms of action of and resistance to antitubulin agents: microtubule dynamics, drug transport, and cell death.
about
An integrated approach to the prediction of chemotherapeutic response in patients with breast cancerThe fate of chemoresistance in triple negative breast cancer (TNBC)Neurodegeneration and microtubule dynamics: death by a thousand cutsNuclear export of proteins and drug resistance in cancerSmall-molecule inhibitors of the Myc oncoproteinMitotic Spindle Disruption by Alternating Electric Fields Leads to Improper Chromosome Segregation and Mitotic Catastrophe in Cancer Cells.Laulimalide induces dose-dependent modulation of microtubule behaviour in the C. elegans embryoHigh expression of class III β-tubulin predicts good response to neoadjuvant taxane and doxorubicin/cyclophosphamide-based chemotherapy in estrogen receptor-negative breast cancerProteasomes are a target of the anti-tumour drug vinblastineA novel synthetic microtubule inhibitor, MPT0B214 exhibits antitumor activity in human tumor cells through mitochondria-dependent intrinsic pathwayA Novel Nitrobenzoate Microtubule Inhibitor that Overcomes Multidrug Resistance Exhibits Antitumor ActivityDoes usnic acid affect microtubules in human cancer cells?Generation and Quantitative Analysis of Pulsed Low Frequency Ultrasound to Determine the Sonic Sensitivity of Untreated and Treated Neoplastic Cells.Isolation, biology and chemistry of the disorazoles: new anti-cancer macrodiolidesDrug resistance associated with loss of p53 involves extensive alterations in microtubule composition and dynamics.Resistance to Taxol in lung cancer cells associated with increased microtubule dynamics.TP53 status and taxane-platinum versus platinum-based therapy in ovarian cancer patients: a non-randomized retrospective study.A novel sulfonamide agent, MPSP-001, exhibits potent activity against human cancer cells in vitro through disruption of microtubule.Epigenetic silencing of microRNA-199b-5p is associated with acquired chemoresistance via activation of JAG1-Notch1 signaling in ovarian cancer.A novel synthetic analog of 5, 8-disubstituted quinazolines blocks mitosis and induces apoptosis of tumor cells by inhibiting microtubule polymerization.Class III β-tubulin is a predictive marker for taxane-based chemotherapy in recurrent and metastatic gastric cancerOrally active microtubule-targeting agent, MPT0B271, for the treatment of human non-small cell lung cancer, alone and in combination with erlotinibThe mechanism of methylselenocysteine and docetaxel synergistic activity in prostate cancer cellsSpecific kinesin expression profiles associated with taxane resistance in basal-like breast cancerMechanisms of Taxol resistance related to microtubules.The cytoskeleton of digestive epithelia in health and disease.Rac1 targeting suppresses p53 deficiency-mediated lymphomagenesis.Decreased levels of baseline and drug-induced tubulin polymerisation are hallmarks of resistance to taxanes in ovarian cancer cells and are associated with epithelial-to-mesenchymal transitionInhibition of hepatic tumor cell proliferation in vitro and tumor growth in vivo by taltobulin, a synthetic analogue of the tripeptide hemiasterlin.Tubulin inhibitors: pharmacophore modeling, virtual screening and molecular docking.A tubulin binding peptide targets glioma cells disrupting their microtubules, blocking migration, and inducing apoptosis.Drug discovery targeting cell division proteins, microtubules and FtsZ.Asymmetric total synthesis of vindorosine, vindoline, and key vinblastine analoguesMethylation-mediated gene silencing as biomarkers of gastric cancer: a review.Pharmacokinetic modeling of an induction regimen for in vivo combined testing of novel drugs against pediatric acute lymphoblastic leukemia xenografts.Clinical activity of enzalutamide in Docetaxel-naïve and Docetaxel-pretreated patients with metastatic castration-resistant prostate cancer.Chemotherapy resistance in metastatic breast cancer: the evolving role of ixabepiloneSpinal astrocytic activation contributes to mechanical allodynia in a rat chemotherapy-induced neuropathic pain model.Novel suicide ligands of tubulin arrest cancer cells in S-phase.Safety and Efficacy of nab-Paclitaxel in the Treatment of Patients with Breast Cancer.
P2860
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P2860
Mechanisms of action of and resistance to antitubulin agents: microtubule dynamics, drug transport, and cell death.
description
1999 nî lūn-bûn
@nan
1999 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի մարտին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Mechanisms of action of and re ...... rug transport, and cell death.
@ast
Mechanisms of action of and re ...... rug transport, and cell death.
@en
Mechanisms of action of and re ...... rug transport, and cell death.
@nl
type
label
Mechanisms of action of and re ...... rug transport, and cell death.
@ast
Mechanisms of action of and re ...... rug transport, and cell death.
@en
Mechanisms of action of and re ...... rug transport, and cell death.
@nl
prefLabel
Mechanisms of action of and re ...... rug transport, and cell death.
@ast
Mechanisms of action of and re ...... rug transport, and cell death.
@en
Mechanisms of action of and re ...... rug transport, and cell death.
@nl
P1476
Mechanisms of action of and re ...... rug transport, and cell death.
@en
P2093
P304
P356
10.1200/JCO.1999.17.3.1061
P407
P577
1999-03-01T00:00:00Z