Antiapoptotic signalling by the insulin-like growth factor I receptor, phosphatidylinositol 3-kinase, and Akt.
about
Combined targeting of mTOR and c-MET signaling pathways for effective management of epithelioid sarcomaA natural ErbB4 isoform that does not activate phosphoinositide 3-kinase mediates proliferation but not survival or chemotaxisRegulation of the Akt/Glycogen synthase kinase-3 axis by insulin-like growth factor-II via activation of the human insulin receptor isoform-AType 1 insulin-like growth factor receptor (IGF-IR) signaling inhibits apoptosis signal-regulating kinase 1 (ASK1)The pro-apoptotic kinase Mst1 and its caspase cleavage products are direct inhibitors of Akt1The p85 regulatory subunit of phosphoinositide 3-kinase down-regulates IRS-1 signaling via the formation of a sequestration complexPhosphoinositide 3-kinase/Akt inhibits MST1-mediated pro-apoptotic signaling through phosphorylation of threonine 120Activation of protein kinase B beta and gamma isoforms by insulin in vivo and by 3-phosphoinositide-dependent protein kinase-1 in vitro: comparison with protein kinase B alphaInhibition of protein kinase B (PKB) and PKCzeta mediates keratin K10-induced cell cycle arrestPKN3 is required for malignant prostate cell growth downstream of activated PI 3-kinase.A PDK1 homolog is necessary and sufficient to transduce AGE-1 PI3 kinase signals that regulate diapause in Caenorhabditis elegansEzrin, a plasma membrane-microfilament linker, signals cell survival through the phosphatidylinositol 3-kinase/Akt pathwayGrb2-associated binder-1 mediates phosphatidylinositol 3-kinase activation and the promotion of cell survival by nerve growth factorCaspase-dependent activation of cyclin-dependent kinases during Fas-induced apoptosis in Jurkat cellsExpression of CX3CR1 chemokine receptors on neurons and their role in neuronal survivalSolenopsin, the alkaloidal component of the fire ant (Solenopsis invicta), is a naturally occurring inhibitor of phosphatidylinositol-3-kinase signaling and angiogenesisThe ELAV RNA-stability factor HuR binds the 5'-untranslated region of the human IGF-IR transcript and differentially represses cap-dependent and IRES-mediated translationAkt kinases in breast cancer and the results of adjuvant therapyFunctional roles and clinical values of insulin-like growth factor-binding protein-5 in different types of cancersAlcohol, insulin resistance and the liver-brain axisKit signaling through PI 3-kinase and Src kinase pathways: an essential role for Rac1 and JNK activation in mast cell proliferationcbl-b inhibits epidermal growth factor receptor signalingLipoarabinomannan from Mycobacterium tuberculosis promotes macrophage survival by phosphorylating Bad through a phosphatidylinositol 3-kinase/Akt pathwayp21-activated kinase 1 phosphorylates the death agonist bad and protects cells from apoptosisActive stromelysin-3 (MMP-11) increases MCF-7 survival in three-dimensional Matrigel culture via activation of p42/p44 MAP-kinaseMitogenic activation, phosphorylation, and nuclear translocation of protein kinase BbetaGrowth factors and insulin stimulate tyrosine phosphorylation of the 51C/SHIP2 proteinInsulin receptor substrate-1 as a signaling molecule for focal adhesion kinase pp125(FAK) and pp60(src)Downregulation of Akt1 inhibits anchorage-independent cell growth and induces apoptosis in cancer cellsEnhancement of susceptibility to diverse skin tumor promoters by activation of the insulin-like growth factor-1 receptor in the epidermis of transgenic miceThe insulin-like growth factor pathway is altered in spinocerebellar ataxia type 1 and type 7RTP801 is induced in Parkinson's disease and mediates neuron death by inhibiting Akt phosphorylation/activationmicroRNA-181a is involved in insulin-like growth factor-1-mediated regulation of the transcription factor CREB1The role of Asp-462 in regulating Akt activityCaenorhabditis elegans Akt/PKB transduces insulin receptor-like signals from AGE-1 PI3 kinase to the DAF-16 transcription factorQualitative regulation of B cell antigen receptor signaling by CD19: selective requirement for PI3-kinase activation, inositol-1,4,5-trisphosphate production and Ca2+ mobilizationTyrosine 1101 of Tie2 is the major site of association of p85 and is required for activation of phosphatidylinositol 3-kinase and Akt4E-BP1, a repressor of mRNA translation, is phosphorylated and inactivated by the Akt(PKB) signaling pathwayPTEN can inhibit in vitro organotypic and in vivo orthotopic invasion of human bladder cancer cells even in the absence of its lipid phosphatase activity.Akt-dependent and -independent survival signaling pathways utilized by insulin-like growth factor I.
P2860
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P2860
Antiapoptotic signalling by the insulin-like growth factor I receptor, phosphatidylinositol 3-kinase, and Akt.
description
1997 nî lūn-bûn
@nan
1997 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի մարտին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
Antiapoptotic signalling by th ...... dylinositol 3-kinase, and Akt.
@ast
Antiapoptotic signalling by th ...... dylinositol 3-kinase, and Akt.
@en
type
label
Antiapoptotic signalling by th ...... dylinositol 3-kinase, and Akt.
@ast
Antiapoptotic signalling by th ...... dylinositol 3-kinase, and Akt.
@en
prefLabel
Antiapoptotic signalling by th ...... dylinositol 3-kinase, and Akt.
@ast
Antiapoptotic signalling by th ...... dylinositol 3-kinase, and Akt.
@en
P2093
P2860
P356
P1476
Antiapoptotic signalling by th ...... dylinositol 3-kinase, and Akt.
@en
P2093
P2860
P304
P356
10.1128/MCB.17.3.1595
P407
P577
1997-03-01T00:00:00Z