CLIP-170 facilitates the formation of kinetochore-microtubule attachments.
about
Tip1/CLIP-170 protein is required for correct chromosome poleward movement in fission yeastPhosphorylation of CLIP-170 by Plk1 and CK2 promotes timely formation of kinetochore-microtubule attachmentsMammalian CLASP1 and CLASP2 cooperate to ensure mitotic fidelity by regulating spindle and kinetochore function.CAMP (C13orf8, ZNF828) is a novel regulator of kinetochore-microtubule attachment.The human spindle assembly checkpoint protein Bub3 is required for the establishment of efficient kinetochore-microtubule attachments.Spindly, a novel protein essential for silencing the spindle assembly checkpoint, recruits dynein to the kinetochoreEB1 regulates attachment of Ska1 with microtubules by forming extended structures on the microtubule latticeBicaudal D2, dynein, and kinesin-1 associate with nuclear pore complexes and regulate centrosome and nuclear positioning during mitotic entryPolo-like kinase 1 phosphorylation of p150Glued facilitates nuclear envelope breakdown during prophaseThe cholangiocyte marker, BD. 1, forms a stable complex with CLIP170 and shares an identity with eIF3a, a multifunctional subunit of the eIF3 initiation complexTubulin tyrosination is a major factor affecting the recruitment of CAP-Gly proteins at microtubule plus ends.Myosin VI is required for targeted membrane transport during cytokinesis.A novel microtubule-modulating noscapinoid triggers apoptosis by inducing spindle multipolarity via centrosome amplification and declustering.Multiple domains of human CLASP contribute to microtubule dynamics and organization in vitro and in Xenopus egg extracts.A protein-tagging system for signal amplification in gene expression and fluorescence imaging.Probing interactions between CLIP-170, EB1, and microtubules.Cdc2-mediated phosphorylation of CLIP-170 is essential for its inhibition of centrosome reduplication.Finding the middle ground: how kinetochores power chromosome congression.Phosphorylation controls autoinhibition of cytoplasmic linker protein-170Cyclin G-associated kinase promotes microtubule outgrowth from chromosomes during spindle assembly.A defect in the CLIP1 gene (CLIP-170) can cause autosomal recessive intellectual disabilityCdk1 and Plk1 mediate a CLASP2 phospho-switch that stabilizes kinetochore-microtubule attachmentsPhosphorylation of EB1 regulates the recruitment of CLIP-170 and p150glued to the plus ends of astral microtubulesMechanisms of Chromosome Congression during Mitosis.The substrates of Plk1, beyond the functions in mitosis.Regulatory mechanisms of kinetochore-microtubule interaction in mitosis.Microtubule plus-ends within a mitotic cell are 'moving platforms' with anchoring, signalling and force-coupling roles.Chromosome misalignments induce spindle-positioning defects.Spindle assembly checkpoint signaling and sister chromatid cohesion are disrupted by HPV E6-mediated transformation.Localized Aurora B activity spatially controls non-kinetochore microtubules during spindle assembly.The role of MACF1 in nervous system development and maintenance.Microtubule-binding protein CLIP-170 is a mediator of paclitaxel sensitivity.Dynein, Lis1 and CLIP-170 counteract Eg5-dependent centrosome separation during bipolar spindle assembly.The chromosomal passenger complex controls spindle checkpoint function independent from its role in correcting microtubule kinetochore interactions.CLIP2 as radiation biomarker in papillary thyroid carcinoma.Misorientation and reduced stretching of aligned sister kinetochores promote chromosome missegregation in EB1- or APC-depleted cells.Plk1 bound to Bub1 contributes to spindle assembly checkpoint activity during mitosis.Regulators of Spindle Microtubules and Their Mechanisms: Living Together Matters.Cytoplasmic Linker Protein CLIP170 Negatively Regulates TLR4 Signaling by Targeting the TLR Adaptor Protein TIRAP.Lateral attachment of kinetochores to microtubules is enriched in prometaphase rosette and facilitates chromosome alignment and bi-orientation establishment.
P2860
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P2860
CLIP-170 facilitates the formation of kinetochore-microtubule attachments.
description
2005 nî lūn-bûn
@nan
2005 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
CLIP-170 facilitates the formation of kinetochore-microtubule attachments.
@ast
CLIP-170 facilitates the formation of kinetochore-microtubule attachments.
@en
type
label
CLIP-170 facilitates the formation of kinetochore-microtubule attachments.
@ast
CLIP-170 facilitates the formation of kinetochore-microtubule attachments.
@en
prefLabel
CLIP-170 facilitates the formation of kinetochore-microtubule attachments.
@ast
CLIP-170 facilitates the formation of kinetochore-microtubule attachments.
@en
P2093
P2860
P356
P1433
P1476
CLIP-170 facilitates the formation of kinetochore-microtubule attachments.
@en
P2093
Marcel A T M van Vugt
Marvin E Tanenbaum
Niels Galjart
P2860
P356
10.1038/SJ.EMBOJ.7600916
P407
P577
2005-12-15T00:00:00Z