Monoubiquitination promotes calpain cleavage of the protein phosphatase 2A (PP2A) regulatory subunit α4, altering PP2A stability and microtubule-associated protein phosphorylation.
about
Protein phosphatase 2A dysfunction in Alzheimer's diseaseSolution structure of the microtubule-targeting COS domain of MID1Visualization of subunit interactions and ternary complexes of protein phosphatase 2A in mammalian cellsXLOS-observed mutations of MID1 Bbox1 domain cause domain unfolding.The ubiquitin E3 ligase NOSIP modulates protein phosphatase 2A activity in craniofacial development.MID1 catalyzes the ubiquitination of protein phosphatase 2A and mutations within its Bbox1 domain disrupt polyubiquitination of alpha4 but not of PP2Ac.TNF-related apoptosis-inducing ligand (TRAIL) regulates midline-1, thymic stromal lymphopoietin, inflammation, and remodeling in experimental eosinophilic esophagitisNovel p75 neurotrophin receptor ligand stabilizes neuronal calcium, preserves mitochondrial movement and protects against HIV associated neuropathogenesisProtein monoubiquitylation: targets and diverse functionsThe MID1 E3 ligase catalyzes the polyubiquitination of Alpha4 (α4), a regulatory subunit of protein phosphatase 2A (PP2A): novel insights into MID1-mediated regulation of PP2A.A computational framework for distinguishing direct versus indirect interactions in human functional protein-protein interaction networks.A Novel Human CAMK2A Mutation Disrupts Dendritic Morphology and Synaptic Transmission, and Causes ASD-Related Behaviors.The tyrosine phosphatase PTPN13/FAP-1 links calpain-2, TBI and tau tyrosine phosphorylation.Expression and regulation of type 2A protein phosphatases and alpha4 signalling in cardiac health and hypertrophyThe E3 ubiquitin ligase midline 1 promotes allergen and rhinovirus-induced asthma by inhibiting protein phosphatase 2A activity.Proteomic View of the Crosstalk between Lactobacillus mucosae and Intestinal Epithelial Cells in Co-culture Revealed by Q Exactive-Based Quantitative Proteomics.Profiling the interactome of protein kinase C ζ by proteomics and bioinformatics.Structural and functional observations of the P151L MID1 mutation reveal alpha4 plays a significant role in X-linked Opitz Syndrome.
P2860
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P2860
Monoubiquitination promotes calpain cleavage of the protein phosphatase 2A (PP2A) regulatory subunit α4, altering PP2A stability and microtubule-associated protein phosphorylation.
description
2012 nî lūn-bûn
@nan
2012 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Monoubiquitination promotes ca ...... iated protein phosphorylation.
@ast
Monoubiquitination promotes ca ...... iated protein phosphorylation.
@en
type
label
Monoubiquitination promotes ca ...... iated protein phosphorylation.
@ast
Monoubiquitination promotes ca ...... iated protein phosphorylation.
@en
prefLabel
Monoubiquitination promotes ca ...... iated protein phosphorylation.
@ast
Monoubiquitination promotes ca ...... iated protein phosphorylation.
@en
P2093
P2860
P356
P1476
Monoubiquitination promotes ca ...... iated protein phosphorylation.
@en
P2093
Benjamin W Spiller
Brian C Kraemer
Brian E Wadzinski
Chris R Guthrie
Guy R Watkins
Matthew D Mazalouskas
Rey J Gomez
Susann Schweiger
P2860
P304
24207-24215
P356
10.1074/JBC.M112.368613
P407
P577
2012-05-21T00:00:00Z