ACAT inhibition reduces the progression of preexisting, advanced atherosclerotic mouse lesions without plaque or systemic toxicity.
about
Cholesterol and lipoprotein metabolism: Early Career Committee contributionCholesterol esters (CE) derived from hepatic sterol O-acyltransferase 2 (SOAT2) are associated with more atherosclerosis than CE from intestinal SOAT2Atherosclerosis and Alzheimer--diseases with a common cause? Inflammation, oxysterols, vasculaturePRD125, a potent and selective inhibitor of sterol O-acyltransferase 2 markedly reduces hepatic cholesteryl ester accumulation and improves liver function in lysosomal acid lipase-deficient miceMyeloid Acyl-CoA:Cholesterol Acyltransferase 1 Deficiency Reduces Lesion Macrophage Content and Suppresses Atherosclerosis ProgressionAcat1 gene ablation in mice increases hematopoietic progenitor cell proliferation in bone marrow and causes leukocytosis.ACAT-1 gene polymorphism is associated with increased susceptibility to coronary artery disease in Chinese Han population: a case-control study.Quantitative Trait Locus Mapping of Macrophage Cholesterol Metabolism and CRISPR/Cas9 Editing Implicate an ACAT1 Truncation as a Causal Modifier Variant.Sterol Metabolism and Transport in Atherosclerosis and Cancer
P2860
Q34081210-CD216093-211B-4E5E-B60A-D8BF5B5BDB70Q34403124-AE117955-70A1-4E72-8FCC-26A6A801B803Q35127516-AB0CF580-D50C-4268-A59E-48D31A9EB799Q36186220-6F87B581-2601-43E4-9F3A-7E938327ED94Q36744704-1160B45C-2FAF-4B88-8FD6-ECCC925E2C9CQ37438808-54FE25DE-3332-4367-882F-EA0FEF78ACBDQ47145343-6CB21E9F-FEA3-4110-9E48-E5234D2D2220Q52429266-BB200455-3663-4575-8FB3-60320865505CQ57072613-A5472E8A-852F-4A4B-8C30-021E1670F9EF
P2860
ACAT inhibition reduces the progression of preexisting, advanced atherosclerotic mouse lesions without plaque or systemic toxicity.
description
2012 nî lūn-bûn
@nan
2012 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
ACAT inhibition reduces the pr ...... t plaque or systemic toxicity.
@ast
ACAT inhibition reduces the pr ...... t plaque or systemic toxicity.
@en
type
label
ACAT inhibition reduces the pr ...... t plaque or systemic toxicity.
@ast
ACAT inhibition reduces the pr ...... t plaque or systemic toxicity.
@en
prefLabel
ACAT inhibition reduces the pr ...... t plaque or systemic toxicity.
@ast
ACAT inhibition reduces the pr ...... t plaque or systemic toxicity.
@en
P2093
P2860
P1476
ACAT inhibition reduces the pr ...... t plaque or systemic toxicity.
@en
P2093
Christine Miller
Courtney Blachford
Edward Thorp
Ilda Bander
James X Rong
Jeffrey Mayne
Jonathan E Feig
Jun Kusunoki
Lawrence L Rudel
P2860
P356
10.1161/ATVBAHA.112.252056
P407
P577
2012-11-08T00:00:00Z