Microtubule alterations occur early in experimental parkinsonism and the microtubule stabilizer epothilone D is neuroprotective - sprookjes - yvandenbroek - TriplyDB

Microtubule alterations occur early in experimental parkinsonism and the microtubule stabilizer epothilone D is neuroprotective

Microtubule alterations occur early in experimental parkinsonism and the microtubule stabilizer epothilone D is neuroprotective

http://www.wikidata.org/entity/Q30539763

about

The Presynaptic Microtubule Cytoskeleton in Physiological and Pathological Conditions: Lessons from Drosophila Fragile X Syndrome and Hereditary Spastic Paraplegias Microtubule-stabilizing agents as potential therapeutics for neurodegenerative disease Nerve growth factor induces neurite outgrowth of PC12 cells by promoting Gβγ-microtubule interaction.α-Synuclein is a Novel Microtubule Dynamase.Epothilone D prevents binge methamphetamine-mediated loss of striatal dopaminergic markers.Caenorhabditis elegans: a model to investigate oxidative stress and metal dyshomeostasis in Parkinson's disease Effects of Microtubule Stabilization by Epothilone B Depend on the Type and Age of Neurons.Branch-Specific Microtubule Destabilization Mediates Axon Branch Loss during Neuromuscular Synapse Elimination.Back to the tubule: microtubule dynamics in Parkinson's disease.Recent progress with microtubule stabilizers: new compounds, binding modes and cellular activities.Microtubule-Targeting Agents Enter the Central Nervous System (CNS): Double-edged Swords for Treating CNS Injury and Disease.Ibuprofen regulation of microtubule dynamics in cystic fibrosis epithelial cells.Aminochrome Toxicity is Mediated by Inhibition of Microtubules Polymerization Through the Formation of Adducts with Tubulin.The cellular basis of dendrite pathology in neurodegenerative diseases.Mitochondrial Metabolism Regulates Microtubule Acetylome and Autophagy Trough Sirtuin-2: Impact for Parkinson's Disease.Microtubule Destabilization Paves the Way to Parkinson's Disease.Altered microtubule dynamics in neurodegenerative disease: Therapeutic potential of microtubule-stabilizing drugs.Neurobiology of axonal transport defects in motor neuron diseases: Opportunities for translational research?Highly Efficient CYP167A1 (EpoK) dependent Epothilone B Formation and Production of 7-Ketone Epothilone D as a New Epothilone Derivative.GRP78 clustering at the cell surface of neurons transduces the action of exogenous alpha-synuclein.Biological Implications of Differential Expression of Mitochondrial-Shaping Proteins in Parkinson's Disease.MPTP Mouse Model of Preclinical and Clinical Parkinson's Disease as an Instrument for Translational Medicine.Microtubule stabilization promoted axonal regeneration and functional recovery after spinal root avulsion.Effect of taxoid and nontaxoid site microtubule-stabilizing agents on axonal transport of mitochondria in untransfected and ECFP-htau40-transfected rat cortical neurons in culture.Cognitive Impairment in a rat model of neuropathic pain: Role of Hippocampal Microtubule Stability.The direct and indirect effects of α-synuclein on microtubule stability in the pathogenesis of Parkinson's disease.Epothilone B Benefits Nigral Dopaminergic Neurons by Attenuating Microglia Activation in the 6-Hydroxydopamine Lesion Mouse Model of Parkinson's Disease Repositioning Microtubule Stabilizing Drugs for Brain Disorders Synthesis of Pironetin-Dumetorine Hybrids as Tubulin Binders

P2860

Q26738451-D2FE0560-9449-4B17-8F42-F475FE058599 Q26865234-7734802B-D9B7-4B93-B8B1-4ED687ED3D68 Q30617387-AD4542C0-EA82-4740-947D-EA4B584B8A38 Q30811315-F0B6B5BA-9BF7-4835-B0EF-01A80543E0F7 Q33583474-BF74ACBD-AC84-4681-AB61-A4EF618D58F3 Q33658107-D387C515-463A-423A-A00F-4AB156C0D678 Q37411688-0041AB06-F4AC-403C-9AE7-88B1E56D72DA Q37463947-63204F82-2198-47CD-806F-7DB2A1CF9C1C Q37590635-EF82DC05-AF40-4C78-8E2F-97255A3EDCC0 Q38183686-8F71C1FE-5085-4443-A69D-6D2233481F31 Q38307155-56606586-7391-4821-B081-5528D3DDD860 Q38763646-D9A38972-CA3D-459C-9434-FE697291F09A Q38837288-51A774D9-A87F-4522-8AAB-731728473E80 Q38922002-3DC293B0-5B2A-4479-9820-7A410A99E2DA Q38974971-3D946F75-495A-4219-A156-56187C7C04B0 Q38984991-75D22D5A-611D-4EA4-957E-CBBAB432ABEA Q39052949-26FABAAF-57A0-4450-85B4-8E15129F215C Q39149919-331A6D4A-E8F8-4F8E-9159-2AD885A74905 Q41141496-613C89DA-7092-413E-BE75-CFAC0F699860 Q42119505-1CD35B4B-0309-4F7F-9332-D731067C2DF3 Q47265377-8326716A-F2C1-4699-BB0B-5AAC87E51B12 Q47891351-20DD9E25-6AB5-4015-A999-3CEB96A2DF2D Q48230835-456B1798-F7DB-449C-81DC-B2B321CB95D2 Q48801607-51697586-8FC8-4AC2-95E3-92B00CE8395C Q52610326-40535708-9C31-4F33-ADB7-D30CCB6008A4 Q55511198-6956F7D4-7246-4E8E-A169-F126FDA77815 Q57490051-D9992EDB-19EC-4B8E-A304-C87B0F2E9D24 Q58795487-4946C99A-8BE3-4578-B173-461AD6A3B5BB Q58880802-08617D21-DA35-4302-B19E-9BBF742DAD48

P2860

Microtubule alterations occur early in experimental parkinsonism and the microtubule stabilizer epothilone D is neuroprotective

http://www.wikidata.org/entity/Q30539763

description

2013 nî lūn-bûn

@nan

2013 թուականի Յունուարին հրատարակուած գիտական յօդուած

@hyw

2013 թվականի հունվարին հրատարակված գիտական հոդված

@hy

2013年の論文

@ja

2013年論文

@yue

2013年論文

@zh-hant

2013年論文

@zh-hk

2013年論文

@zh-mo

2013年論文

@zh-tw

2013年论文

@wuu

name

Microtubule alterations occur ...... pothilone D is neuroprotective

@ast

Microtubule alterations occur ...... pothilone D is neuroprotective

@en

type

label

Microtubule alterations occur ...... pothilone D is neuroprotective

@ast

Microtubule alterations occur ...... pothilone D is neuroprotective

@en

prefLabel

Microtubule alterations occur ...... pothilone D is neuroprotective

@ast

Microtubule alterations occur ...... pothilone D is neuroprotective

@en

P1433

Q30539763-55A7D934-39C8-4C39-9AA9-95E1CB2F517E

P1476

Q30539763-83BE36D7-50E5-4D57-92DE-861D5235D8E5

P2093

Q30539763-04086D4B-DE24-4AEE-8043-8CE8D0DC07BB

Q30539763-2369F92D-F831-4F8E-A52C-EC57EACF1D92

Q30539763-30E8D1A5-EE94-433A-B32C-1A78106A5968

Q30539763-43252C8D-5A1F-4E9D-8540-BFF637DA6719

Q30539763-4E164F42-46E0-472F-8216-C7D83909F7FE

Q30539763-55E3B497-4CEB-48BC-9A10-2649CFC86D22

Q30539763-6F69C478-22B6-41A6-96AE-E95FBAB5F05C

Q30539763-7E79B0B8-0C6D-4D24-901D-BBE43087E909

Q30539763-CA4BB4CF-0A1A-4395-AC9A-8C1CEACF2BFB

Q30539763-DCBF7B3A-0372-4F46-8613-1F4F0FA09FAC

P2860

Q30539763-07A1AE39-F3C2-440B-92F6-41536040DB53

Q30539763-09B332EC-DE68-4B11-8F0F-F1C4AF17481E

Q30539763-0D45311B-D3F0-4213-BA7D-47CA0E8B891F

Q30539763-10094DE5-6A6A-47C6-8EF4-9BEA34EEC145

Q30539763-188BB011-BF9B-43FF-BC53-920B825BAE22

Q30539763-189B869D-6FE7-4157-A268-48E0EFFEF46B

Q30539763-1A405E89-80D1-4238-A64E-D6974DCB46C5

Q30539763-1FE81059-27C5-4B42-973E-82107FAC1284

Q30539763-2138A053-4397-4DE9-975B-29A1BB0192D7

Q30539763-2AB215A1-0F97-465E-B173-26B7990E31A2

P2888

Q30539763-48EDCA2F-5FA3-4059-A1D5-CA0C73F11521

P304

Q30539763-91A88037-FCED-463F-80D4-67A53F9FF0C5

P31

Q30539763-943DBC1D-7D8A-431E-B3C6-0582957AC234

P356

Q30539763-62055390-DE70-4B87-BDBB-97D821517F06

P407

Q30539763-5543A5B2-B52E-40AF-8C49-A3833A8B13A8

P478

Q30539763-24CCFAE3-662E-4890-B0BA-A49459B7609E

P50

Q30539763-528A42C1-9A63-477B-8BDE-7EE0251044F0

P577

Q30539763-1346369C-5666-497F-B5CE-A2D0DF75B204

P5875

Q30539763-70F8CFBE-42B5-4037-B7C3-F14D04C75FB8

P6179

Q30539763-EA92279B-DD3B-4DB6-AD5C-79704A425623

P698

Q30539763-B190423D-70F1-43AD-9AEA-12993ADE0983

P921

Q30539763-51E35235-9E79-4A7F-89A2-FEFB01EE3A96

Q30539763-646CA261-C9FA-4F04-A732-31A5B2A88BFE

P932

Q30539763-25668C2C-0C3E-4A0A-8E93-2EE11BFABD9B

P356

P1433

Scientific Reports

P1476

Microtubule alterations occur ...... pothilone D is neuroprotective

@en

P2093

Anna Traficante

http://www.w3.org/2001/XMLSchema#string

Carla Letizia Busceti

http://www.w3.org/2001/XMLSchema#string

Daniele Cartelli

http://www.w3.org/2001/XMLSchema#string

Daniele Passarella

http://www.w3.org/2001/XMLSchema#string

Domenico Bucci

http://www.w3.org/2001/XMLSchema#string

Erminio Giavini

http://www.w3.org/2001/XMLSchema#string

Francesca Casagrande

http://www.w3.org/2001/XMLSchema#string

Gemma Molinaro

http://www.w3.org/2001/XMLSchema#string

Giuseppe Battaglia

http://www.w3.org/2001/XMLSchema#string

Graziella Cappelletti

http://www.w3.org/2001/XMLSchema#string

P2860

Protein measurement with the Folin phenol reagent

PINK1 and Parkin target Miro for phosphorylation and degradation to arrest mitochondrial motility

A family of protein-deglutamylating enzymes associated with neurodegeneration

Parkinsonian neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and alpha-synuclein mutations promote Tau protein phosphorylation at Ser262 and destabilize microtubule cytoskeleton in vitro

Are tubulin isotypes functionally significant

Microtubule acetylation promotes kinesin-1 binding and transport.

Role of axonal transport in neurodegenerative diseases

A guided tour into subcellular colocalization analysis in light microscopy

Parkinson's disease: mechanisms and models

Dynamic instability of microtubule growth

P2888

P304

1837

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1038/SREP01837

http://www.w3.org/2001/XMLSchema#string

P407

P478

3

http://www.w3.org/2001/XMLSchema#string

P50

P577

2013-01-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

236740406

http://www.w3.org/2001/XMLSchema#string

P6179

1024691195

http://www.w3.org/2001/XMLSchema#string

P698

23670541

http://www.w3.org/2001/XMLSchema#string

P921

Parkinson's disease

P932

3653217

http://www.w3.org/2001/XMLSchema#string