Unique oxidative mechanisms for the reactive nitrogen oxide species, nitroxyl anion. - sprookjes - yvandenbroek - TriplyDB

Unique oxidative mechanisms for the reactive nitrogen oxide species, nitroxyl anion.

Unique oxidative mechanisms for the reactive nitrogen oxide species, nitroxyl anion.

http://www.wikidata.org/entity/Q31478644

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Nitroxyl (HNO): A Reduced Form of Nitric Oxide with Distinct Chemical, Pharmacological, and Therapeutic Properties Synthesis, characterization and antioxidant activity of new copper(I) complexes of scorpionate and water soluble phosphane ligands.Nitroxyl and its anion in aqueous solutions: spin states, protic equilibria, and reactivities toward oxygen and nitric oxide Nitroxyl anion exerts redox-sensitive positive cardiac inotropy in vivo by calcitonin gene-related peptide signaling.Reactions of HNO with heme proteins: new routes to HNO-heme complexes and insight into physiological effects.The reduction potential of nitric oxide (NO) and its importance to NO biochemistry.Flavorubredoxin, an inducible catalyst for nitric oxide reduction and detoxification in Escherichia coli.Glutathione sulfinamide serves as a selective, endogenous biomarker for nitroxyl after exposure to therapeutic levels of donors.Nitroxyl (HNO) reacts with molecular oxygen and forms peroxynitrite at physiological pH. Biological Implications.The specificity of nitroxyl chemistry is unique among nitrogen oxides in biological systems.HNO and NO release from a primary amine-based diazeniumdiolate as a function of pH Positive inotropic and lusitropic effects of HNO/NO- in failing hearts: independence from beta-adrenergic signaling.Orthogonal properties of the redox siblings nitroxyl and nitric oxide in the cardiovascular system: a novel redox paradigm.A biochemical rationale for the discrete behavior of nitroxyl and nitric oxide in the cardiovascular system.Nitric oxide and cell signaling: modulation of redox tone and protein modification.Methods for detection of reactive metabolites of oxygen and nitrogen: in vitro and in vivo considerations.The chemistry and biology of nitroxyl (HNO): a chemically unique species with novel and important biological activity.Biological signaling by small inorganic molecules The pharmacology of nitroxyl (HNO) and its therapeutic potential: not just the Janus face of NO Generation of nitroxyl by heme protein-mediated peroxidation of hydroxylamine but not N-hydroxy-L-arginine.A mosquito 2-Cys peroxiredoxin protects against nitrosative and oxidative stresses associated with malaria parasite infection Identification of nitroxyl-induced modifications in human platelet proteins using a novel mass spectrometric detection method.Therapeutic Potential of Nitroxyl (HNO) Donors in the Management of Acute Decompensated Heart Failure.The chemical biology of HNO signaling.Assessment of the effect of Allium sativum on serum nitric oxide level and hepatic histopathology in experimental cystic echinococcosis in mice.Nitroxyl accelerates the oxidation of oxyhemoglobin by nitrite Induction of heme oxygenase 1 by nitrosative stress. A role for nitroxyl anion.Nitroxyl anion regulation of the NMDA receptor.Nitrogen dioxide oxidizes mitochondrial cytochrome c.Copper,zinc superoxide dismutase as a univalent NO(-) oxidoreductase and as a dichlorofluorescin peroxidase.Formation of peroxynitrite from reaction of nitroxyl anion with molecular oxygen.Formation of nitroxyl and hydroxyl radical in solutions of sodium trioxodinitrate: effects of pH and cytotoxicity.Angeli's salt and spinal motor neuron injury.Consequences of MnSOD interactions with nitric oxide: nitric oxide dismutation and the generation of peroxynitrite and hydrogen peroxide.

P2860

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P2860

Unique oxidative mechanisms for the reactive nitrogen oxide species, nitroxyl anion.

http://www.wikidata.org/entity/Q31478644

description

2000 nî lūn-bûn

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2000 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

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Unique oxidative mechanisms for the reactive nitrogen oxide species, nitroxyl anion.

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Unique oxidative mechanisms for the reactive nitrogen oxide species, nitroxyl anion.

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Unique oxidative mechanisms for the reactive nitrogen oxide species, nitroxyl anion.

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Unique oxidative mechanisms for the reactive nitrogen oxide species, nitroxyl anion.

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Unique oxidative mechanisms for the reactive nitrogen oxide species, nitroxyl anion.

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Unique oxidative mechanisms for the reactive nitrogen oxide species, nitroxyl anion.

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Journal of Biological Chemistry

P1476

Unique oxidative mechanisms for the reactive nitrogen oxide species, nitroxyl anion.

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P2093

Espey MG

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Feelisch M

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Fukuto JM

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Grisham MB

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Jourd'heuil D

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Kim S

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Krishna M

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P2860

One- and two-electron oxidations of methionine by peroxynitrite

The reaction of no with superoxide

Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide

The decomposition of peroxynitrite to nitroxyl anion (NO-) and singlet oxygen in aqueous solution

Formation of free nitric oxide from l-arginine by nitric oxide synthase: direct enhancement of generation by superoxide dismutase.

Opposite effects of nitric oxide and nitroxyl on postischemic myocardial injury.

The cytotoxicity of nitroxyl: possible implications for the pathophysiological role of NO.

The effect of various nitric oxide-donor agents on hydrogen peroxide-mediated toxicity: a direct correlation between nitric oxide formation and protection.

Reaction between S-nitrosothiols and thiols: generation of nitroxyl (HNO) and subsequent chemistry.

Attenuation of NMDA receptor activity and neurotoxicity by nitroxyl anion, NO-.

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1720-1727

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10.1074/JBC.M006174200

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3

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276

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11042174

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