Tissue-specific dysregulation of cortisol metabolism in human obesity.
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Cortisol release from adipose tissue by 11beta-hydroxysteroid dehydrogenase type 1 in humansThe role of glucocorticoid action in the pathophysiology of the Metabolic SyndromeAdrenalectomy stimulates hypothalamic proopiomelanocortin expression but does not correct diet-induced obesityRelationships between Rodent White Adipose Fat Pads and Human White Adipose Fat DepotsInteractions between sleep, stress, and metabolism: From physiological to pathological conditionsEnzymatic intracrine regulation of white adipose tissueSalicylate downregulates 11β-HSD1 expression in adipose tissue in obese mice and in humans, mediating insulin sensitizationEffects of proportions of dietary macronutrients on glucocorticoid metabolism in diet-induced obesity in ratsSystemic metabolic derangement, pulmonary effects, and insulin insufficiency following subchronic ozone exposure in rats,The obesity pandemic: where have we been and where are we going?11beta-hydroxysteroid dehydrogenase type 1 inhibitors for the treatment of type 2 diabetes.Inhibition of 11betaHSD1 with the S-phenylethylaminothiazolone BVT116429 increases adiponectin concentrations and improves glucose homeostasis in diabetic KKAy miceTissue-specific increases in 11beta-hydroxysteroid dehydrogenase type 1 in normal weight postmenopausal women.Adipocyte-specific glucocorticoid inactivation protects against diet-induced obesityInhibiting endogenous cortisol blunts the meal-entrained rise in serum leptin.Fructose, Glucocorticoids and Adipose Tissue: Implications for the Metabolic Syndrome.Relative hypo- and hypercortisolism are both associated with depression and lower quality of life in bipolar disorder: a cross-sectional study.Metabolic syndrome without obesity: Hepatic overexpression of 11beta-hydroxysteroid dehydrogenase type 1 in transgenic miceStress and obesity: the role of the hypothalamic-pituitary-adrenal axis in metabolic diseaseReference intervals for plasma concentrations of adrenal steroids measured by LC-MS/MS: Impact of gender, age, oral contraceptives, body mass index and blood pressure statusThe 11-beta-hydroxysteroid dehydrogenase type 1 inhibitor INCB13739 improves hyperglycemia in patients with type 2 diabetes inadequately controlled by metformin monotherapy.A novel 11β-hydroxysteroid dehydrogenase type1 inhibitor CNX-010-49 improves hyperglycemia, lipid profile and reduces body weight in diet induced obese C57B6/J mice with a potential to provide cardio protective benefits.Neonatal overfeeding induced by small litter rearing causes altered glucocorticoid metabolism in rats.Glucocorticoids increase adipocytes in muscle by affecting IL-4 regulated FAP activity.A nonlinear relationship of generalized and central obesity with diurnal cortisol secretion in the Whitehall II study.Hypothalamic-pituitary-adrenal axis function: relative contributions of perceived stress and obesity in women.Central glucocorticoid administration promotes weight gain and increased 11β-hydroxysteroid dehydrogenase type 1 expression in white adipose tissueEffect of restorative yoga vs. stretching on diurnal cortisol dynamics and psychosocial outcomes in individuals with the metabolic syndrome: the PRYSMS randomized controlled trial.Recycling between cortisol and cortisone in human splanchnic, subcutaneous adipose, and skeletal muscle tissues in vivo.Short-term, low-dose GH therapy improves insulin sensitivity without modifying cortisol metabolism and ectopic fat accumulation in adults with GH deficiency11β-Hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitors still improve metabolic phenotype in male 11β-HSD1 knockout mice suggesting off-target mechanisms.BVT.2733, a selective 11β-hydroxysteroid dehydrogenase type 1 inhibitor, attenuates obesity and inflammation in diet-induced obese miceLXRβ is required for glucocorticoid-induced hyperglycemia and hepatosteatosis in mice.Carbenoxolone treatment ameliorated metabolic syndrome in WNIN/Ob obese rats, but induced severe fat loss and glucose intolerance in lean rats.Increased whole-body and sustained liver cortisol regeneration by 11beta-hydroxysteroid dehydrogenase type 1 in obese men with type 2 diabetes provides a target for enzyme inhibitionEffects of antisense-mediated inhibition of 11β-hydroxysteroid dehydrogenase type 1 on hepatic lipid metabolism11β-hydroxysteroid dehydrogenase types 1 and 2 activity in subcutaneous adipose tissue in humans: implications in obesity and diabetes.Pro-inflammatory cytokine induction of 11β-hydroxysteroid dehydrogenase type 1 in A549 cells requires phosphorylation of C/EBPβ at Thr235Adrenal and gonadal function in obesity.Association of cortisol and the metabolic syndrome in Korean men and women
P2860
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P2860
Tissue-specific dysregulation of cortisol metabolism in human obesity.
description
2001 nî lūn-bûn
@nan
2001 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի մարտին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Tissue-specific dysregulation of cortisol metabolism in human obesity.
@ast
Tissue-specific dysregulation of cortisol metabolism in human obesity.
@en
type
label
Tissue-specific dysregulation of cortisol metabolism in human obesity.
@ast
Tissue-specific dysregulation of cortisol metabolism in human obesity.
@en
prefLabel
Tissue-specific dysregulation of cortisol metabolism in human obesity.
@ast
Tissue-specific dysregulation of cortisol metabolism in human obesity.
@en
P2093
P356
P1476
Tissue-specific dysregulation of cortisol metabolism in human obesity.
@en
P2093
P304
P356
10.1210/JCEM.86.3.7453
P407
P577
2001-03-01T00:00:00Z