Sphingosine kinase expression regulates apoptosis and caspase activation in PC12 cells.
about
Phosphorylation-dependent translocation of sphingosine kinase to the plasma membrane drives its oncogenic signallingA house divided: ceramide, sphingosine, and sphingosine-1-phosphate in programmed cell deathSphingolipid signaling in metabolic disordersTranscription factor specificity protein 1 (Sp1) is the main regulator of nerve growth factor-induced sphingosine kinase 1 gene expression of the rat pheochromocytoma cell line, PC12Characterization of murine sphingosine-1-phosphate phosphohydrolaseSphingosine Kinase 2 Deficiency Attenuates Kidney Fibrosis via IFN-γ.Sphingosine kinase type 2 inhibition elevates circulating sphingosine 1-phosphate.Divergent roles of sphingosine kinases in kidney ischemia-reperfusion injury.Sphingosine-1-phosphate receptors: biology and therapeutic potential in kidney diseaseApoptotic effect of sphingosine 1-phosphate and increased sphingosine 1-phosphate hydrolysis on mesangial cells cultured at low cell density.Overexpression of sphingosine kinase 1 is associated with salivary gland carcinoma progression and might be a novel predictive marker for adjuvant therapy.Pharmacology and antitumor activity of ABC294640, a selective inhibitor of sphingosine kinase-2The S1P2 receptor negatively regulates platelet-derived growth factor-induced motility and proliferation.Isoflurane protects human kidney proximal tubule cells against necrosis via sphingosine kinase and sphingosine-1-phosphate generationMammalian sphingosine kinase (SphK) isoenzymes and isoform expression: challenges for SphK as an oncotarget.Sphingosine kinase 1 in cancer.S1P metabolism in cancer and other pathological conditions.Sphingosine kinase 1 regulates the Akt/FOXO3a/Bim pathway and contributes to apoptosis resistance in glioma cells.SphK1 confers resistance to apoptosis in gastric cancer cells by downregulating Bim via stimulating Akt/FoxO3a signaling.Sphingosine 1-phosphate, a key cell signaling molecule.Suppression of colitis-driven colon cancer in mice by a novel small molecule inhibitor of sphingosine kinaseCancer treatment strategies targeting sphingolipid metabolism.Extracellular sphingosine-1-phosphate: a novel actor in human glioblastoma stem cell survivalA sphingosine kinase form 2 knockout sensitizes mouse myocardium to ischemia/reoxygenation injury and diminishes responsiveness to ischemic preconditioning.Skeletal muscle triglycerides, diacylglycerols, and ceramides in insulin resistance: another paradox in endurance-trained athletes?Targeting sphingosine kinase-1 to inhibit melanoma.Expression of SphK1 impairs degranulation and motility of RBL-2H3 mast cells by desensitizing S1P receptors.Autophagosomal membrane serves as platform for intracellular death-inducing signaling complex (iDISC)-mediated caspase-8 activation and apoptosis.Sphingosine kinase signalling in immune cells.G protein-coupled receptor roles in cell migration and cell death decisions.Overexpression of sphingosine kinase 1 prevents ceramide accumulation and ameliorates muscle insulin resistance in high-fat diet-fed mice.Molecular biology of the nasal airways: how do we assess cellular and molecular responses in the nose?FTY720 postconditions isolated perfused heart by a mechanism independent of sphingosine kinase 2 and different from S1P or ischemic postconditioning.Distribution of sphingosine kinase activity and mRNA in rodent brain.The role of sphingosine-1-phosphate and its receptors in asthma.Cellular effect of high doses of silica-coated quantum dot profiled with high throughput gene expression analysis and high content cellomics measurements.Reduced sphingosine kinase-1 and enhanced sphingosine 1-phosphate lyase expression demonstrate deregulated sphingosine 1-phosphate signaling in Alzheimer's disease.Reduction of COX-2 through modulating miR-124/SPHK1 axis contributes to the antimetastatic effect of alpinumisoflavone in melanoma.Sphingolipids: key regulators of apoptosis and pivotal players in cancer drug resistanceSphingosine kinases/sphingosine-1-phosphate and death Signalling in APP-transfected cells.
P2860
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P2860
Sphingosine kinase expression regulates apoptosis and caspase activation in PC12 cells.
description
2001 nî lūn-bûn
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2001 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի մարտին հրատարակված գիտական հոդված
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2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Sphingosine kinase expression regulates apoptosis and caspase activation in PC12 cells.
@ast
Sphingosine kinase expression regulates apoptosis and caspase activation in PC12 cells.
@en
type
label
Sphingosine kinase expression regulates apoptosis and caspase activation in PC12 cells.
@ast
Sphingosine kinase expression regulates apoptosis and caspase activation in PC12 cells.
@en
prefLabel
Sphingosine kinase expression regulates apoptosis and caspase activation in PC12 cells.
@ast
Sphingosine kinase expression regulates apoptosis and caspase activation in PC12 cells.
@en
P2093
P1476
Sphingosine kinase expression regulates apoptosis and caspase activation in PC12 cells.
@en
P2093
P304
P356
10.1046/J.1471-4159.2001.00164.X
P407
P577
2001-03-01T00:00:00Z