Sequence determinants of enhanced amyloidogenicity of Alzheimer A{beta}42 peptide relative to A{beta}40.
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Calcium-Sensing Receptors of Human Neural Cells Play Crucial Roles in Alzheimer's DiseaseCommon mechanisms involved in Alzheimer's disease and type 2 diabetes: a key role of chronic bacterial infection and inflammationDementia of the eye: the role of amyloid beta in retinal degenerationAxonal transport of APP and the spatial regulation of APP cleavage and function in neuronal cellsEngineering amyloid-like assemblies from unstructured peptides via site-specific lipid conjugationA revisited folding reporter for quantitative assay of protein misfolding and aggregation in mammalian cells.Techniques for Monitoring Protein Misfolding and Aggregation in Vitro and in Living CellsEffects of membrane interaction and aggregation of amyloid β-peptide on lipid mobility and membrane domain structure.Requirement of aggregation propensity of Alzheimer amyloid peptides for neuronal cell surface binding.New molecular reporters for rapid protein folding assaysCritical structural and functional roles for the N-terminal insertion sequence in surfactant protein B analogs.The complexities underlying age-related macular degeneration: could amyloid beta play an important role?Calcium signaling and amyloid toxicity in Alzheimer disease.Genome-wide analysis of Saccharomyces cerevisiae identifies cellular processes affecting intracellular aggregation of Alzheimer's amyloid-β42: importance of lipid homeostasis.Intrinsic disorder modulates protein self-assembly and aggregation.Morphological diversity and polymorphism of self-assembling collagen peptides controlled by length of hydrophobic domainsMutations that replace aromatic side chains promote aggregation of the Alzheimer's Aβ peptide.Generic hydrophobic residues are sufficient to promote aggregation of the Alzheimer's Abeta42 peptide.Single-channel Ca(2+) imaging implicates Aβ1-42 amyloid pores in Alzheimer's disease pathologyAmyloid-beta aggregation.Differences in β-strand populations of monomeric Aβ40 and Aβ42.Cytotoxicity of intracellular aβ42 amyloid oligomers involves Ca2+ release from the endoplasmic reticulum by stimulated production of inositol trisphosphate.Neuronal protein trafficking associated with Alzheimer disease: from APP and BACE1 to glutamate receptorsThe structure of Abeta42 C-terminal fragments probed by a combined experimental and theoretical study.The culprit behind amyloid beta peptide related neurotoxicity in Alzheimer's disease: oligomer size or conformation?Membrane and surface interactions of Alzheimer's Aβ peptide--insights into the mechanism of cytotoxicity.Emerging roles of pathogens in Alzheimer disease.Misfolding of amyloidogenic proteins and their interactions with membranes.Structure of ring-shaped Aβ₄₂ oligomers determined by conformational selection.Mutations enhance the aggregation propensity of the Alzheimer's A beta peptideImaging the Intracellular Trafficking of APP with Photoactivatable GFP.Amide solvent protection analysis demonstrates that amyloid-beta(1-40) and amyloid-beta(1-42) form different fibrillar structures under identical conditionsDetermining the critical nucleus and mechanism of fibril elongation of the Alzheimer's Abeta(1-40) peptide.Two distinct conformations of Abeta aggregates on the surface of living PC12 cells.Why and how protein aggregation has to be studied in vivo.Full length amylin oligomer aggregation: insights from molecular dynamics simulations and implications for design of aggregation inhibitors.Comparing the Aggregation Free Energy Landscapes of Amyloid Beta(1-42) and Amyloid Beta(1-40).Dimorphic aggregation behavior of a fusion polypeptide incorporating a stable protein domain (EGFP) with an amyloidogenic sequence (retroCspA).Reassessment of inclusion body-based production as a versatile opportunity for difficult-to-express recombinant proteins.Effect of a Paramagnetic Spin Label on the Intrinsically Disordered Peptide Ensemble of Amyloid-β.
P2860
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P2860
Sequence determinants of enhanced amyloidogenicity of Alzheimer A{beta}42 peptide relative to A{beta}40.
description
2005 nî lūn-bûn
@nan
2005 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Sequence determinants of enhan ...... peptide relative to A{beta}40.
@ast
Sequence determinants of enhan ...... peptide relative to A{beta}40.
@en
type
label
Sequence determinants of enhan ...... peptide relative to A{beta}40.
@ast
Sequence determinants of enhan ...... peptide relative to A{beta}40.
@en
prefLabel
Sequence determinants of enhan ...... peptide relative to A{beta}40.
@ast
Sequence determinants of enhan ...... peptide relative to A{beta}40.
@en
P2860
P356
P1476
Sequence determinants of enhan ...... peptide relative to A{beta}40.
@en
P2093
Michael H Hecht
Woojin Kim
P2860
P304
35069-35076
P356
10.1074/JBC.M505763200
P407
P577
2005-08-03T00:00:00Z