Similar patterns of mitochondrial vulnerability and rescue induced by genetic modification of alpha-synuclein, parkin, and DJ-1 in Caenorhabditis elegans.
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alpha-Synuclein and neuronal cell deathRac1 protein rescues neurite retraction caused by G2019S leucine-rich repeat kinase 2 (LRRK2)The role of oxidative stress in Parkinson's diseaseRNA binding activity of the recessive parkinsonism protein DJ-1 supports involvement in multiple cellular pathwaysHuman DJ-1 and its homologs are novel glyoxalasesMitochondrial localization of DJ-1 leads to enhanced neuroprotectionMutant LRRK2 elicits calcium imbalance and depletion of dendritic mitochondria in neuronsBile acids: regulation of apoptosis by ursodeoxycholic acidEvaluation of Models of Parkinson's DiseaseUsing C. elegans to discover therapeutic compounds for ageing-associated neurodegenerative diseasesPathologic and therapeutic implications for the cell biology of parkinThe Unexpected Uses of Urso- and Tauroursodeoxycholic Acid in the Treatment of Non-liver DiseasesMechanisms of aging-related proteinopathies in Caenorhabditis elegansExtracellular dopamine potentiates mn-induced oxidative stress, lifespan reduction, and dopaminergic neurodegeneration in a BLI-3-dependent manner in Caenorhabditis elegansBacteria, yeast, worms, and flies: exploiting simple model organisms to investigate human mitochondrial diseasesThe PINK1/Parkin pathway regulates mitochondrial morphologyAntipurinergic therapy corrects the autism-like features in the Fragile X (Fmr1 knockout) mouse model.DJ-1 knock-down impairs astrocyte mitochondrial function.A microfluidic phenotype analysis system reveals function of sensory and dopaminergic neuron signaling in C. elegans electrotactic swimming behavior.Evolutionary conservation of drug action on lipoprotein metabolism-related targets.DJ-1 modulates alpha-synuclein aggregation state in a cellular model of oxidative stress: relevance for Parkinson's disease and involvement of HSP70.Environmental exposure, obesity, and Parkinson's disease: lessons from fat and old worms.Cerebrotendinous xanthomatosis patients with and without parkinsonism: clinical characteristics and neuroimaging findings.Caenorhabditis elegans: a model to investigate oxidative stress and metal dyshomeostasis in Parkinson's diseaseDJ-1, PINK1, and their effects on mitochondrial pathwaysBehavioral Phenotyping and Pathological Indicators of Parkinson's Disease in C. elegans Models.Watching worms whither: modeling neurodegeneration in C. elegans.Parkinson's disease: insights from pathways.A plant DJ-1 homolog is essential for Arabidopsis thaliana chloroplast development.Identification and characterization of a novel endogenous murine parkin mutation.Molecular mechanisms of pesticide-induced neurotoxicity: Relevance to Parkinson's disease.Unravelling the role of defective genes.D-beta-hydroxybutyrate extends lifespan in C. elegans.C. elegans epidermal wounding induces a mitochondrial ROS burst that promotes wound repairDJ-1 acts in parallel to the PINK1/parkin pathway to control mitochondrial function and autophagy.Co-administration of betulinic acid and methamphetamine causes toxicity to dopaminergic and serotonergic nerve terminals in the striatum of late adolescent ratsHuman disease models in Drosophila melanogaster and the role of the fly in therapeutic drug discovery.Rhomboid-7 and HtrA2/Omi act in a common pathway with the Parkinson's disease factors Pink1 and Parkin.Ursocholanic acid rescues mitochondrial function in common forms of familial Parkinson's disease.LRRK2 modulates vulnerability to mitochondrial dysfunction in Caenorhabditis elegans
P2860
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P2860
Similar patterns of mitochondrial vulnerability and rescue induced by genetic modification of alpha-synuclein, parkin, and DJ-1 in Caenorhabditis elegans.
description
2005 nî lūn-bûn
@nan
2005 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
name
Similar patterns of mitochondr ...... J-1 in Caenorhabditis elegans.
@ast
Similar patterns of mitochondr ...... J-1 in Caenorhabditis elegans.
@en
type
label
Similar patterns of mitochondr ...... J-1 in Caenorhabditis elegans.
@ast
Similar patterns of mitochondr ...... J-1 in Caenorhabditis elegans.
@en
prefLabel
Similar patterns of mitochondr ...... J-1 in Caenorhabditis elegans.
@ast
Similar patterns of mitochondr ...... J-1 in Caenorhabditis elegans.
@en
P2093
P2860
P356
P1476
Similar patterns of mitochondr ...... J-1 in Caenorhabditis elegans.
@en
P2093
Aixa Alfonso
Anne Sluder
Benjamin Wolozin
Beth Westlund
Cecilia Mp Rodrigues
Celine Perier
Clifford Steer
Lucinda Burnam
P2860
P304
42655-42668
P356
10.1074/JBC.M505910200
P407
P577
2005-10-19T00:00:00Z