Cytotoxic effects induced by docetaxel, gefitinib, and cyclopamine on side population and nonside population cell fractions from human invasive prostate cancer cells.
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Targeting the Sonic Hedgehog Signaling Pathway: Review of Smoothened and GLI InhibitorsMolecular biomarkers of cancer stem/progenitor cells associated with progression, metastases, and treatment resistance of aggressive cancersEmergence of zebrafish models in oncology for validating novel anticancer drug targets and nanomaterialsProstate Cancer Stem Cells: Research AdvancesPolymer-drug conjugates: origins, progress to date and future directionsHypoxia-inducing factors as master regulators of stemness properties and altered metabolism of cancer- and metastasis-initiating cellsChemoresistance in prostate cancer cells is regulated by miRNAs and Hedgehog pathwaySRC kinase regulation in progressively invasive cancerPathobiological implications of the expression of EGFR, pAkt, NF-κB and MIC-1 in prostate cancer stem cells and their progeniesMUC4 down-regulation reverses chemoresistance of pancreatic cancer stem/progenitor cells and their progeniesNew promising drug targets in cancer- and metastasis-initiating cells.Frequent deregulations in the hedgehog signaling network and cross-talks with the epidermal growth factor receptor pathway involved in cancer progression and targeted therapies.Novel therapies against aggressive and recurrent epithelial cancers by molecular targeting tumor- and metastasis-initiating cells and their progenies.Cyclopamine attenuates acute warm ischemia reperfusion injury in cholestatic rat liver: hope for marginal liversTargeting the notch ligand JAGGED1 in both tumor cells and stroma in ovarian cancer.Frequent gene products and molecular pathways altered in prostate cancer- and metastasis-initiating cells and their progenies and novel promising multitargeted therapies.Combination of cyclopamine and tamoxifen promotes survival and migration of mcf-7 breast cancer cells--interaction of hedgehog-gli and estrogen receptor signaling pathways.Inhibition of hedgehog signaling improves the anti-carcinogenic effects of docetaxel in prostate cancer.Selective inhibitory effect of HPMA copolymer-cyclopamine conjugate on prostate cancer stem cells.In vitro and in vivo antitumoral effects of combinations of polyphenols, or polyphenols and anticancer drugs: perspectives on cancer treatmentAnimal models relevant to human prostate carcinogenesis underlining the critical implication of prostatic stem/progenitor cells.Targeting the unique methylation pattern of androgen receptor (AR) promoter in prostate stem/progenitor cells with 5-aza-2'-deoxycytidine (5-AZA) leads to suppressed prostate tumorigenesis.Marked improvement of cytotoxic effects induced by docetaxel on highly metastatic and androgen-independent prostate cancer cells by downregulating macrophage inhibitory cytokine-1.Hedgehog signaling in prostate cancer and its therapeutic implicationHPMA copolymer-based combination therapy toxic to both prostate cancer stem/progenitor cells and differentiated cells induces durable anti-tumor effects.Altered gene products involved in the malignant reprogramming of cancer stem/progenitor cells and multitargeted therapies.Cancer stem cells: the development of new cancer therapeutics.The emerging role of the phosphatidylinositol 3-kinase/ akt/mammalian target of rapamycin signaling network in cancer stem cell biology.Fact or fiction--identifying the elusive multiple myeloma stem cell.Development of anticancer agents targeting the Hedgehog signaling.Biological characteristics of a cell subpopulation in tongue squamous cell carcinoma.The Hedgehog-GLI pathway in embryonic development and cancer: implications for pulmonary oncology therapy.GANT-61 and GDC-0449 induce apoptosis of prostate cancer stem cells through a GLI-dependent mechanism.Transplantation of periodontal ligament cell sheets expressing human β‑defensin‑3 promotes anti‑inflammation in a canine model of periodontitis.Taxane resistance in castration-resistant prostate cancer: mechanisms and therapeutic strategies
P2860
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P2860
Cytotoxic effects induced by docetaxel, gefitinib, and cyclopamine on side population and nonside population cell fractions from human invasive prostate cancer cells.
description
2010 nî lūn-bûn
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2010 թուականի Փետրուարին հրատարակուած գիտական յօդուած
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2010 թվականի փետրվարին հրատարակված գիտական հոդված
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2010年の論文
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2010年学术文章
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2010年学术文章
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2010年学术文章
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2010年学术文章
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name
Cytotoxic effects induced by d ...... nvasive prostate cancer cells.
@ast
Cytotoxic effects induced by d ...... nvasive prostate cancer cells.
@en
Cytotoxic effects induced by d ...... nvasive prostate cancer cells.
@nl
type
label
Cytotoxic effects induced by d ...... nvasive prostate cancer cells.
@ast
Cytotoxic effects induced by d ...... nvasive prostate cancer cells.
@en
Cytotoxic effects induced by d ...... nvasive prostate cancer cells.
@nl
prefLabel
Cytotoxic effects induced by d ...... nvasive prostate cancer cells.
@ast
Cytotoxic effects induced by d ...... nvasive prostate cancer cells.
@en
Cytotoxic effects induced by d ...... nvasive prostate cancer cells.
@nl
P2093
P2860
P1476
Cytotoxic effects induced by d ...... nvasive prostate cancer cells.
@en
P2093
Jean-Pierre Henichart
Murielle Mimeault
Patrick Depreux
Sonny L Johansson
Surinder K Batra
P2860
P304
P356
10.1158/1535-7163.MCT-09-1013
P577
2010-02-23T00:00:00Z