In situ click chemistry: probing the binding landscapes of biological molecules.
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Biotin Protein Ligase Is a Target for New AntibacterialsSynthesis and Chemistry of Organic Geminal Di- and TriazidesIn situ click chemistry: from small molecule discovery to synthetic antibodiesA virtual screen discovers novel, fragment-sized inhibitors of Mycobacterium tuberculosis InhARapid preparation of triazolyl substituted NH-heterocyclic kinase inhibitors via one-pot Sonogashira coupling-TMS-deprotection-CuAAC sequenceGeneration of Candidate Ligands for Nicotinic Acetylcholine Receptors via in situ Click Chemistry with a Soluble Acetylcholine Binding Protein TemplateObservation of the controlled assembly of preclick components in the in situ click chemistry generation of a chitinase inhibitorKinetic target-guided synthesis in drug discovery and chemical biology: a comprehensive facts and figures surveyA Mechanochemically Triggered "Click" Catalyst.Optical reading of contaminants in aqueous media based on gold nanoparticles.Palladium-catalyzed regioselective azidation of allylic C-H bonds under atmospheric pressure of dioxygen.A recyclable and reusable supported Cu(I) catalyzed azide-alkyne click polymerization.In situ click chemistry generation of cyclooxygenase-2 inhibitors.Detection of 5-hydroxymethylcytosine in DNA by transferring a keto-glucose by using T4 phage β-glucosyltransferase18F-labeling using click cycloadditions.Multispectral labeling of antibodies with polyfluorophores on a DNA backbone and application in cellular imagingTemplate-directed synthesis of a small molecule-antisense conjugate targeting an mRNA structure.Screening of protein-protein interaction modulators via sulfo-click kinetic target-guided synthesistrans,trans-2,4-Hexadiene incorporation on enzymes for site-specific immobilization and fluorescent labeling.Applying small molecule microarrays and resulting affinity probe cocktails for proteome profiling of mammalian cell lysates.CuAAC click chemistry accelerates the discovery of novel chemical scaffolds as promising protein tyrosine phosphatases inhibitorsOne-pot three-step synthesis of 1,2,3-triazoles by copper-catalyzed cycloaddition of azides with alkynes formed by a Sonogashira cross-coupling and desilylation.The impact of click chemistry in medicinal chemistry.Fast hydrazone reactants: electronic and acid/base effects strongly influence rate at biological pH.Target deconvolution techniques in modern phenotypic profiling.Bringing chemistry to life.Synthesis of carbocyclic nucleoside analogs with five-membered heterocyclic nucleobases.Regulation of cell physiology and pathology by protein S-glutathionylation: lessons learned from the cardiovascular system.Color-Coded Super-Resolution Small-Molecule Imaging.A new application of click chemistry in situ: development of fluorescent probe for specific G-quadruplex topologyBioorthogonal labeling of 5-hydroxymethylcytosine in genomic DNA and diazirine-based DNA photo-cross-linking probes.Transition metal-mediated synthesis of monocyclic aromatic heterocyclesAutomated docking with protein flexibility in the design of femtomolar "click chemistry" inhibitors of acetylcholinesterase.Advancements in the mechanistic understanding of the copper-catalyzed azide-alkyne cycloaddition.Click Chemistry and Radiochemistry: The First 10 YearsSingle-step Radiosyntheses of '(18)F-Labeled Click Synthons' from Azide-functionalized Diaryliodonium SaltsApplication of click chemistry on preparation of separation materials for liquid chromatography.Chemical contrast for imaging living systems: molecular vibrations drive CARS microscopy.Steroid/triterpenoid functional molecules based on "click chemistry".Green chemistry oriented organic synthesis in water.
P2860
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P2860
In situ click chemistry: probing the binding landscapes of biological molecules.
description
2010 nî lūn-bûn
@nan
2010 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի մարտին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
In situ click chemistry: probing the binding landscapes of biological molecules.
@ast
In situ click chemistry: probing the binding landscapes of biological molecules.
@en
In situ click chemistry: probing the binding landscapes of biological molecules.
@nl
type
label
In situ click chemistry: probing the binding landscapes of biological molecules.
@ast
In situ click chemistry: probing the binding landscapes of biological molecules.
@en
In situ click chemistry: probing the binding landscapes of biological molecules.
@nl
prefLabel
In situ click chemistry: probing the binding landscapes of biological molecules.
@ast
In situ click chemistry: probing the binding landscapes of biological molecules.
@en
In situ click chemistry: probing the binding landscapes of biological molecules.
@nl
P356
P1476
In situ click chemistry: probing the binding landscapes of biological molecules.
@en
P2093
Sreeman K Mamidyala
P2860
P304
P356
10.1039/B901969N
P50
P577
2010-03-01T00:00:00Z