TbetaR-II discriminates the high- and low-affinity TGF-beta isoforms via two hydrogen-bonded ion pairs - sprookjes - yvandenbroek - TriplyDB

TbetaR-II discriminates the high- and low-affinity TGF-beta isoforms via two hydrogen-bonded ion pairs

TbetaR-II discriminates the high- and low-affinity TGF-beta isoforms via two hydrogen-bonded ion pairs

http://www.wikidata.org/entity/Q33572051

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TGF-β signalling is mediated by two autonomously functioning TβRI:TβRII pairs Oligomeric interactions of TGF-β and BMP receptors Ternary Complex of Transforming Growth Factor- 1 Reveals Isoform-specific Ligand Recognition and Receptor Recruitment in the Superfamily The T?R-I Pre-Helix Extension Is Structurally Ordered in the Unbound Form and Its Flanking Prolines Are Essential for Binding An engineered transforming growth factor β (TGF-β) monomer that functions as a dominant negative to block TGF-β signaling Slow, reversible, coupled folding and binding of the spectrin tetramerization domain.TGFβ2 regulates hypothalamic Trh expression through the TGFβ inducible early gene-1 (TIEG1) during fetal development.A Short Peptide That Mimics the Binding Domain of TGF-β1 Presents Potent Anti-Inflammatory Activity Transforming growth factor-β3 promotes facial nerve injury repair in rabbits Transforming Growth Factor-β Family Ligands Can Function as Antagonists by Competing for Type II Receptor Binding.Betaglycan has two independent domains required for high affinity TGF-beta binding: proteolytic cleavage separates the domains and inactivates the neutralizing activity of the soluble receptor.TGF-β and its coreceptors in cancerogenesis: an overview.Production, Isolation, and Structural Analysis of Ligands and Receptors of the TGF-β Superfamily.Structural Biology and Evolution of the TGF-β Family Expression of TGFβ3 and its effects on migratory and invasive behavior of prostate cancer cells: involvement of PI3-kinase/AKT signaling pathway.Divergence(s) in nodal signaling between aggressive melanoma and embryonic stem cells.Biological activity differences between TGF-β1 and TGF-β3 correlate with differences in the rigidity and arrangement of their component monomers.Binding Properties of the Transforming Growth Factor-β Coreceptor Betaglycan: Proposed Mechanism for Potentiation of Receptor Complex Assembly and Signaling.Survey of the 2009 commercial optical biosensor literature.Differential role of PTEN in transforming growth factor β (TGF-β) effects on proliferation and migration in prostate cancer cells.

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TbetaR-II discriminates the high- and low-affinity TGF-beta isoforms via two hydrogen-bonded ion pairs

http://www.wikidata.org/entity/Q33572051

description

2009 nî lūn-bûn

@nan

2009 թուականի Մարտին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի մարտին հրատարակված գիտական հոդված

@hy

2009年の論文

@ja

2009年論文

@yue

2009年論文

@zh-hant

2009年論文

@zh-hk

2009年論文

@zh-mo

2009年論文

@zh-tw

2009年论文

@wuu

name

TbetaR-II discriminates the hi ...... two hydrogen-bonded ion pairs

@ast

TbetaR-II discriminates the hi ...... two hydrogen-bonded ion pairs

@en

TbetaR-II discriminates the hi ...... two hydrogen-bonded ion pairs.

@nl

type

label

TbetaR-II discriminates the hi ...... two hydrogen-bonded ion pairs

@ast

TbetaR-II discriminates the hi ...... two hydrogen-bonded ion pairs

@en

TbetaR-II discriminates the hi ...... two hydrogen-bonded ion pairs.

@nl

prefLabel

TbetaR-II discriminates the hi ...... two hydrogen-bonded ion pairs

@ast

TbetaR-II discriminates the hi ...... two hydrogen-bonded ion pairs

@en

TbetaR-II discriminates the hi ...... two hydrogen-bonded ion pairs.

@nl

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TbetaR-II discriminates the hi ...... two hydrogen-bonded ion pairs

@en

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Andrew P Hinck

http://www.w3.org/2001/XMLSchema#string

Cynthia S Hinck

http://www.w3.org/2001/XMLSchema#string

Jason Baardsnes

http://www.w3.org/2001/XMLSchema#string

Maureen D O'Connor-McCourt

http://www.w3.org/2001/XMLSchema#string

P2860

TGF-beta signal transduction

Cooperative assembly of TGF-beta superfamily signaling complexes is mediated by two disparate mechanisms and distinct modes of receptor binding

TGF beta signals through a heteromeric protein kinase receptor complex

The crystal structure of TGF-beta 3 and comparison to TGF-beta 2: implications for receptor binding

Crystal structure of the human TbetaR2 ectodomain--TGF-beta3 complex

Structures of an ActRIIB:activin A complex reveal a novel binding mode for TGF-beta ligand:receptor interactions

The BMP7/ActRII extracellular domain complex provides new insights into the cooperative nature of receptor assembly

Gradient-tailored excitation for single-quantum NMR spectroscopy of aqueous solutions

Real-time monitoring of the interactions of transforming growth factor-beta (TGF-beta ) isoforms with latency-associated protein and the ectodomains of the TGF-beta type II and III receptors reveals different kinetic models and stoichiometries of bi

Targeted disruption of the mouse transforming growth factor-beta 1 gene results in multifocal inflammatory disease

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scholarly article

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10.1021/BI8019004

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10

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2009-03-01T00:00:00Z

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19161338

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2801812

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