Betaglycan has two independent domains required for high affinity TGF-beta binding: proteolytic cleavage separates the domains and inactivates the neutralizing activity of the soluble receptor.
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TGF-β signalling is mediated by two autonomously functioning TβRI:TβRII pairsIdentification of a Novel TGF-β-Binding Site in the Zona Pellucida C-terminal (ZP-C) Domain of TGF-β-Receptor-3 (TGFR-3)Receptor cleavage reduces the fluid shear response in neutrophils of the spontaneously hypertensive ratFibroblast growth factor-2 promotes in vitro mitral valve interstitial cell repair through transforming growth factor-β/Smad signaling.Proteolytic control of TGF-β co-receptor activity by BMP-1/tolloid-like proteases revealed by quantitative iTRAQ proteomics.Altering the Proteoglycan State of Transforming Growth Factor β Type III Receptor (TβRIII)/Betaglycan Modulates Canonical Wnt/β-Catenin Signaling.Production, Isolation, and Structural Analysis of Ligands and Receptors of the TGF-β Superfamily.Signaling Receptors for TGF-β Family Members.Structural Biology and Evolution of the TGF-β FamilyBiological activity differences between TGF-β1 and TGF-β3 correlate with differences in the rigidity and arrangement of their component monomers.The type III TGF-β receptor betaglycan transmembrane-cytoplasmic domain fragment is stable after ectodomain cleavage and is a substrate of the intramembrane protease γ-secretase.Binding Properties of the Transforming Growth Factor-β Coreceptor Betaglycan: Proposed Mechanism for Potentiation of Receptor Complex Assembly and Signaling.Survey of the 2009 commercial optical biosensor literature.Betaglycan knock-down causes embryonic angiogenesis defects in zebrafish.ALK1 signaling in development and disease: new paradigms.
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P2860
Betaglycan has two independent domains required for high affinity TGF-beta binding: proteolytic cleavage separates the domains and inactivates the neutralizing activity of the soluble receptor.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on December 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Betaglycan has two independent ...... ivity of the soluble receptor.
@en
Betaglycan has two independent ...... ivity of the soluble receptor.
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type
label
Betaglycan has two independent ...... ivity of the soluble receptor.
@en
Betaglycan has two independent ...... ivity of the soluble receptor.
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prefLabel
Betaglycan has two independent ...... ivity of the soluble receptor.
@en
Betaglycan has two independent ...... ivity of the soluble receptor.
@nl
P2093
P2860
P356
P1433
P1476
Betaglycan has two independent ...... tivity of the soluble receptor
@en
P2093
Fernando López-Casillas
Guillermo Mendoza-Hernández
M Magdalena Vilchis-Landeros
Maria M Villarreal
Valentín Mendoza
P2860
P304
11755-11765
P356
10.1021/BI901528W
P407
P577
2009-12-01T00:00:00Z