Production of oxidative DNA damage during the metabolic activation of benzo[a]pyrene in human mammary epithelial cells correlates with cell killing
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Evidence for the aldo-keto reductase pathway of polycyclic aromatic trans-dihydrodiol activation in human lung A549 cellsDNA single strand breakage, DNA adducts, and sister chromatid exchange in lymphocytes and phenanthrene and pyrene metabolites in urine of coke oven workers.Modulation of 3-methylcholanthrene toxicity in cultured neoplastic keratinocytes by glucocorticoids and retinoids is not accounted for by macromolecular adduct formation.Defective repair of oxidative base lesions by the DNA glycosylase Nth1 associates with multiple telomere defects.Mechanisms of cell injury by activated oxygen speciesOxidative and non-oxidative DNA damage and cardiovascular disease.Glaucarubulone glucoside from Castela macrophylla suppresses MCF-7 breast cancer cell growth and attenuates benzo[a]pyrene-mediated CYP1A gene induction.The attenuation of early benzo(a)pyrene-induced carcinogenic insults by diallyl disulfide (DADS) in MCF-10A cells.Diallyl trisulfide as an inhibitor of benzo(a)pyrene-induced precancerous carcinogenesis in MCF-10A cells.Global genome removal of thymine glycol in Escherichia coli requires endonuclease III but the persistence of processed repair intermediates rather than thymine glycol correlates with cellular sensitivity to high doses of hydrogen peroxide.Factors influencing elevation of intracellular Ca2+ in the MCF-10A human mammary epithelial cell line by carcinogenic polycyclic aromatic hydrocarbons.ATSDR evaluation of health effects of chemicals. IV. Polycyclic aromatic hydrocarbons (PAHs): understanding a complex problem.Polycyclic aromatic hydrocarbon (PAH) o-quinones produced by the aldo-keto-reductases (AKRs) generate abasic sites, oxidized pyrimidines, and 8-oxo-dGuo via reactive oxygen speciesFormation of 8-oxo-7,8-dihydro-2'-deoxyguanosine (8-oxo-dGuo) by PAH o-quinones: involvement of reactive oxygen species and copper(II)/copper(I) redox cycling.Inhibition of BRCA-1 expression by benzo[a]pyrene and its diol epoxide.In vitro and in vivo studies on oxygen free radical and DNA adduct formation in rat lung and liver during benzo[a]pyrene metabolism.Cellular ras protooncogene expression in human mammary explant cultures. A potential marker for chemical carcinogenesis.Polycyclic aromatic hydrocarbons (PAH) [MAK Value Documentation, 2012]
P2860
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P2860
Production of oxidative DNA damage during the metabolic activation of benzo[a]pyrene in human mammary epithelial cells correlates with cell killing
description
1988 nî lūn-bûn
@nan
1988 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1988 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1988年の論文
@ja
1988年論文
@yue
1988年論文
@zh-hant
1988年論文
@zh-hk
1988年論文
@zh-mo
1988年論文
@zh-tw
1988年论文
@wuu
name
Production of oxidative DNA da ...... s correlates with cell killing
@ast
Production of oxidative DNA da ...... s correlates with cell killing
@en
Production of oxidative DNA da ...... correlates with cell killing.
@nl
type
label
Production of oxidative DNA da ...... s correlates with cell killing
@ast
Production of oxidative DNA da ...... s correlates with cell killing
@en
Production of oxidative DNA da ...... correlates with cell killing.
@nl
prefLabel
Production of oxidative DNA da ...... s correlates with cell killing
@ast
Production of oxidative DNA da ...... s correlates with cell killing
@en
Production of oxidative DNA da ...... correlates with cell killing.
@nl
P2093
P2860
P356
P1476
Production of oxidative DNA da ...... s correlates with cell killing
@en
P2093
M R Stampfer
S A Leadon
P2860
P304
P356
10.1073/PNAS.85.12.4365
P407
P577
1988-06-01T00:00:00Z