about
TGF-β and BMP signaling in osteoblast differentiation and bone formationProteinase-Activated Receptor 2 Is a Novel Regulator of TGF-β Signaling in Pancreatic CancerTransforming Growth Factor-Beta and Oxidative Stress Interplay: Implications in Tumorigenesis and Cancer ProgressionGenetic variation in the TGF-β signaling pathway and colon and rectal cancer risk.Linking patient outcome to high throughput protein expression data identifies novel regulators of colorectal adenocarcinoma aggressivenessSMAD4--molecular gladiator of the TGF-beta signaling is trampled upon by mutational insufficiency in colorectal carcinoma of Kashmiri population: an analysis with relation to KRAS proto-oncogene.'Druggable' alterations detected by Ion Torrent in metastatic colorectal cancer patientsThe effect of transforming growth factor-beta1 on nasopharyngeal carcinoma cells: insensitive to cell growth but functional to TGF-beta/Smad pathwayThe regulation of TGF-β/SMAD signaling by protein deubiquitination.Appreciating the broad clinical features of SMAD4 mutation carriers: a multicenter chart review.Computational analysis of expression of human embryonic stem cell-associated signatures in tumors.Reproducible combinatorial regulatory networks elucidate novel oncogenic microRNAs in non-small cell lung cancerSMAD4 is a potential prognostic marker in human breast carcinomas.Myocardial deletion of Smad4 using a novel α skeletal muscle actin Cre recombinase transgenic mouse causes misalignment of the cardiac outflow tractAnterior visceral endoderm SMAD4 signaling specifies anterior embryonic patterning and head induction in mice.Functional screening for miRNAs targeting Smad4 identified miR-199a as a negative regulator of TGF-β signalling pathway.Oncogenic miRNA-182-5p targets Smad4 and RECK in human bladder cancer.MicroRNA-224 targets SMAD family member 4 to promote cell proliferation and negatively influence patient survival.A pathway approach to evaluating the association between the CHIEF pathway and risk of colorectal cancer.Coordinate microRNA-mediated regulation of protein complexes in prostate cancer.Smad4 loss synergizes with TGFα overexpression in promoting pancreatic metaplasia, PanIN development, and fibrosis.Integrated approaches to miRNAs target definition: time-series analysis in an osteosarcoma differentiative model.Transforming growth factor beta signaling in adult cardiovascular diseases and repair.Lysophosphatidic acid-induced p21Waf1 expression mediates the cytostatic response of breast and ovarian cancer cells to TGFβ.Hsa-miR-301a-3p Acts as an Oncogene in Laryngeal Squamous Cell Carcinoma via Target Regulation of Smad4MiR-130a-3p regulates cell migration and invasion via inhibition of Smad4 in gemcitabine resistant hepatoma cells.Genistein downregulates onco-miR-1260b and inhibits Wnt-signalling in renal cancer cells.Cystatin E/M Suppresses Tumor Cell Growth through Cytoplasmic Retention of NF-κB.Smad4 suppresses the tumorigenesis and aggressiveness of neuroblastoma through repressing the expression of heparanaseExpression and clinical significance of the transforming growth factor-β signalling pathway in endometrial cancer.Postnatal ablation of osteoblast Smad4 enhances proliferative responses to canonical Wnt signaling through interactions with β-catenin.Gastric Lgr5(+) stem cells are the cellular origin of invasive intestinal-type gastric cancer in mice.miR-888 is an expressed prostatic secretions-derived microRNA that promotes prostate cell growth and migration.Primary urethral clear-cell adenocarcinoma: comprehensive analysis by surgical pathology, cytopathology, and next-generation sequencingUpregulation of MiR-205 transcriptionally suppresses SMAD4 and PTEN and contributes to human ovarian cancer progression.Important molecular genetic markers of colorectal cancer.Epigenome-Wide DNA Methylation Profiling Identifies Differential Methylation Biomarkers in High-Grade Bladder CancerGenistein downregulates onco-miR-1260b and upregulates sFRP1 and Smad4 via demethylation and histone modification in prostate cancer cells.BxPC3 pancreatic cancer cells express a truncated Smad4 protein upon PI3K and mTOR inhibition.Genetic variants in the TGFβ-signaling pathway influence expression of miRNAs in colon and rectal normal mucosa and tumor tissue.
P2860
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P2860
description
2010 nî lūn-bûn
@nan
2010 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Smad4-mediated TGF-beta signaling in tumorigenesis.
@ast
Smad4-mediated TGF-beta signaling in tumorigenesis.
@en
type
label
Smad4-mediated TGF-beta signaling in tumorigenesis.
@ast
Smad4-mediated TGF-beta signaling in tumorigenesis.
@en
prefLabel
Smad4-mediated TGF-beta signaling in tumorigenesis.
@ast
Smad4-mediated TGF-beta signaling in tumorigenesis.
@en
P2860
P921
P356
P1476
Smad4-mediated TGF-beta signaling in tumorigenesis.
@en
P2093
P2860
P356
10.7150/IJBS.6.1
P407
P50
P5008
P577
2010-01-01T00:00:00Z