Evidence for distinct signaling properties and biological responses induced by the PDGF receptor alpha and beta subtypes.
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Src family kinases negatively regulate platelet-derived growth factor alpha receptor-dependent signaling and disease progressionDisruption of platelet-derived growth factor-dependent phosphatidylinositol 3-kinase and phospholipase Cγ 1 activity abolishes vascular smooth muscle cell proliferation and migration and attenuates neointima formation in vivoPI3-kinase/Akt-dependent antiapoptotic signaling by the PDGF alpha receptor is negatively regulated by Src family kinasesPlatelet-derived growth factor D is activated by urokinase plasminogen activator in prostate carcinoma cells.Haptotactic migration induced by midkine. Involvement of protein-tyrosine phosphatase zeta. Mitogen-activated protein kinase, and phosphatidylinositol 3-kinaseStage specificity of novel growth factor expression during development of proliferative vitreoretinopathy.Tyrosine kinase inhibitor SU6668 represses chondrosarcoma growth via antiangiogenesis in vivo.Nanofibrous scaffolds incorporating PDGF-BB microspheres induce chemokine expression and tissue neogenesis in vivo.Phase I and pharmacokinetic study of TSU-68, a novel multiple receptor tyrosine kinase inhibitor, by twice daily oral administration between meals in patients with advanced solid tumorsRegulation of the proliferation and differentiation of Leydig stem cells in the adult testis.Reversal of experimental pulmonary hypertension by PDGF inhibition.Growth factor-dependent signaling and cell cycle progression.A potential oncogenic activity of platelet-derived growth factor d in prostate cancer progressionRasGAP Promotes Autophagy and Thereby Suppresses Platelet-Derived Growth Factor Receptor-Mediated Signaling Events, Cellular Responses, and Pathology.Leucine motif-dependent tyrosine autophosphorylation of type III receptor tyrosine kinases.Inhibitory effects of resveratrol on PDGF-BB-induced retinal pigment epithelial cell migration via PDGFRβ, PI3K/Akt and MAPK pathways.RhoB regulates PDGFR-beta trafficking and signaling in vascular smooth muscle cells.Hypoxic pulmonary hypertension in mice with constitutively active platelet-derived growth factor receptor-β.Platelet-derived growth factor beta receptor regulates interstitial fluid homeostasis through phosphatidylinositol-3' kinase signalingMammary tumors that become independent of the type I insulin-like growth factor receptor express elevated levels of platelet-derived growth factor receptors.Platelet-derived growth factor-C (PDGF-C) activation by serine proteases: implications for breast cancer progressionMulti-omics analysis reveals regulators of the response to PDGF-BB treatment in pulmonary artery smooth muscle cells.Gene therapeutics for periodontal regenerative medicine.Inhibition of platelet-derived growth factor signalling induces autophagy in malignant glioma cellsRole of growth factors on periodontal repair.Effect of rhPDGF-BB delivery on mediators of periodontal wound repair.Characterization of the platelet transcriptome by RNA sequencing in patients with acute myocardial infarction.Recent developments in our understanding of how platelet-derived growth factor (PDGF) and its receptors contribute to proliferative vitreoretinopathy.Imatinib mesylate for the treatment of pulmonary arterial hypertension.Advanced reconstructive technologies for periodontal tissue repair.Novel investigational therapies for treating pulmonary arterial hypertension.Platelet-derived growth factor-receptor alpha strongly inhibits melanoma growth in vitro and in vivo.Growth factors outside of the platelet-derived growth factor (PDGF) family employ reactive oxygen species/Src family kinases to activate PDGF receptor alpha and thereby promote proliferation and survival of cells.Phosphatidylinositol 3-kinase-dependent membrane recruitment of Rac-1 and p47phox is critical for alpha-platelet-derived growth factor receptor-induced production of reactive oxygen species.Binding of Cbl to a phospholipase Cgamma1-docking site on platelet-derived growth factor receptor beta provides a dual mechanism of negative regulation.Multiple growth factor induction of a murine early response gene that complements a lethal defect in yeast ribosome biogenesis.Identification of the receptor-associated signaling enzymes that are required for platelet-derived growth factor-AA-dependent chemotaxis and DNA synthesis.Genetic Ablation of PDGF-Dependent Signaling Pathways Abolishes Vascular Remodeling and Experimental Pulmonary HypertensionEngineering of tooth-supporting structures by delivery of PDGF gene therapy vectors.Gene transfer and expression of platelet-derived growth factors modulate periodontal cellular activity.
P2860
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P2860
Evidence for distinct signaling properties and biological responses induced by the PDGF receptor alpha and beta subtypes.
description
1999 nî lūn-bûn
@nan
1999 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի հունվարին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Evidence for distinct signalin ...... eptor alpha and beta subtypes.
@ast
Evidence for distinct signalin ...... eptor alpha and beta subtypes.
@en
type
label
Evidence for distinct signalin ...... eptor alpha and beta subtypes.
@ast
Evidence for distinct signalin ...... eptor alpha and beta subtypes.
@en
prefLabel
Evidence for distinct signalin ...... eptor alpha and beta subtypes.
@ast
Evidence for distinct signalin ...... eptor alpha and beta subtypes.
@en
P921
P1476
Evidence for distinct signalin ...... eptor alpha and beta subtypes.
@en
P2093
Kazlauskas A
Rosenkranz S
P304
P356
10.3109/08977199909002130
P577
1999-01-01T00:00:00Z