Transmembrane helices 1 and 6 of the human breast cancer resistance protein (BCRP/ABCG2): identification of polar residues important for drug transport.
about
The multidrug transporter ABCG2: still more questions than answersJump into a New Fold-A Homology Based Model for the ABCG2/BCRP Multidrug TransporterIdentification of proline residues in or near the transmembrane helices of the human breast cancer resistance protein (BCRP/ABCG2) that are important for transport activity and substrate specificity.Role of the breast cancer resistance protein (BCRP/ABCG2) in drug transport--an update.Three-dimensional structure of the human breast cancer resistance protein (BCRP/ABCG2) in an inward-facing conformation.Structure and function of BCRP, a broad specificity transporter of xenobiotics and endobiotics.GW583340 and GW2974, human EGFR and HER-2 inhibitors, reverse ABCG2- and ABCB1-mediated drug resistance.Mutations of charged amino acids at the cytoplasmic end of transmembrane helix 2 affect transport activity of the budding yeast multidrug resistance protein Pdr5p.Residues contributing to drug transport by ABCG2 are localised to multiple drug-binding pockets.
P2860
Q26747187-DABB5E0C-F458-46F5-9868-B5E5E6395CD8Q28552715-2ACE908A-DCD2-4E7D-9956-71DEA18EE0B9Q33997565-E0B05C9C-B6C5-47B2-90F9-F0D99CB1F222Q34871636-D1EA01CA-DF17-4C28-AE86-1945E0C33BC5Q35927508-2F02B7DD-CFFA-40A1-86E6-BECB4C7A3D83Q38207943-2CCAAD45-CF1D-4503-A0D0-41D564DF40F3Q39380536-9A549B78-0C11-4B41-8E98-3F42CCD702ADQ50327949-74DB221C-AA0D-4EC5-B86C-27809861653AQ53694857-024FB1B4-5A10-4D93-AF75-C55297FE1321
P2860
Transmembrane helices 1 and 6 of the human breast cancer resistance protein (BCRP/ABCG2): identification of polar residues important for drug transport.
description
2010 nî lūn-bûn
@nan
2010 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Transmembrane helices 1 and 6 ...... important for drug transport.
@ast
Transmembrane helices 1 and 6 ...... important for drug transport.
@en
type
label
Transmembrane helices 1 and 6 ...... important for drug transport.
@ast
Transmembrane helices 1 and 6 ...... important for drug transport.
@en
prefLabel
Transmembrane helices 1 and 6 ...... important for drug transport.
@ast
Transmembrane helices 1 and 6 ...... important for drug transport.
@en
P2093
P2860
P1476
Transmembrane helices 1 and 6 ...... important for drug transport.
@en
P2093
Mark F Rosenberg
Qingcheng Mao
Xiaokun Cai
Zhanglin Ni
Zsolt Bikadi
P2860
P304
P356
10.1152/AJPCELL.00160.2010
P577
2010-08-25T00:00:00Z