MAPK signaling is required for dedifferentiation of acinar cells and development of pancreatic intraepithelial neoplasia in mice.
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Reserve stem cells: Differentiated cells reprogram to fuel repair, metaplasia, and neoplasia in the adult gastrointestinal tractSilencing Mist1 Gene Expression Is Essential for Recovery from Acute PancreatitisTherapeutic potential of targeting acinar cell reprogramming in pancreatic cancerRegulation of Cellular Identity in CancerInflammation and Epithelial-Mesenchymal Transition in Pancreatic Ductal Adenocarcinoma: Fighting Against Multiple OpponentsThe secret origins and surprising fates of pancreas tumorsMicroRNAs of the mir-17~92 cluster regulate multiple aspects of pancreatic tumor development and progression.PI3K regulation of RAC1 is required for KRAS-induced pancreatic tumorigenesis in mice.Deregulation of the MiR-193b-KRAS Axis Contributes to Impaired Cell Growth in Pancreatic CancerThe basic helix-loop-helix transcription factor E47 reprograms human pancreatic cancer cells to a quiescent acinar state with reduced tumorigenic potential.The acinar differentiation determinant PTF1A inhibits initiation of pancreatic ductal adenocarcinomaMitogen-activated Protein Kinase Kinase Activity Maintains Acinar-to-Ductal Metaplasia and Is Required for Organ Regeneration in Pancreatitis.Myeloid cells are required for PD-1/PD-L1 checkpoint activation and the establishment of an immunosuppressive environment in pancreatic cancerInflammation as a driver and vulnerability of KRAS mediated oncogenesisAcinar cell plasticity and development of pancreatic ductal adenocarcinoma.Growth hormone receptor inhibition decreases the growth and metastasis of pancreatic ductal adenocarcinoma.Targeting reactive oxygen species in development and progression of pancreatic cancer.Epithelial-Myeloid cell crosstalk regulates acinar cell plasticity and pancreatic remodeling in mice.Luteolin inhibits pancreatitis‑induced acinar‑ductal metaplasia, proliferation and epithelial‑mesenchymal transition of acinar cells.β2 Adrenergic-Neurotrophin Feedforward Loop Promotes Pancreatic Cancer.Pancreatic Cancer Screening.Krüppel-like Factor 5, Increased in Pancreatic Ductal Adenocarcinoma, Promotes Proliferation, Acinar to Ductal Metaplasia, Pancreatic Intraepithelial Neoplasia, and Tumor Growth in Mice.Mutant p53R270H drives altered metabolism and increased invasion in pancreatic ductal adenocarcinoma.ETV5 regulates ductal morphogenesis with Sox9 and is critical for regeneration from pancreatitis.Induced PTF1a expression in pancreatic ductal adenocarcinoma cells activates acinar gene networks, reduces tumorigenic properties, and sensitizes cells to gemcitabine treatment.Cholinergic Signaling via Muscarinic Receptors Directly and Indirectly Suppresses Pancreatic Tumorigenesis and Cancer StemnessStabilization of HIF-2α impacts pancreas growthPlasticity of differentiated cells in wound repair and tumorigenesis, part II: skin and intestineGenome-scale analysis to identify prognostic microRNA biomarkers in patients with early stage pancreatic ductal adenocarcinoma after pancreaticoduodenectomy
P2860
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P2860
MAPK signaling is required for dedifferentiation of acinar cells and development of pancreatic intraepithelial neoplasia in mice.
description
2013 nî lūn-bûn
@nan
2013 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
MAPK signaling is required for ...... aepithelial neoplasia in mice.
@ast
MAPK signaling is required for ...... aepithelial neoplasia in mice.
@en
type
label
MAPK signaling is required for ...... aepithelial neoplasia in mice.
@ast
MAPK signaling is required for ...... aepithelial neoplasia in mice.
@en
prefLabel
MAPK signaling is required for ...... aepithelial neoplasia in mice.
@ast
MAPK signaling is required for ...... aepithelial neoplasia in mice.
@en
P2093
P2860
P1433
P1476
MAPK signaling is required for ...... aepithelial neoplasia in mice.
@en
P2093
Judith S Sebolt-Leopold
Marina Pasca di Magliano
Meredith A Collins
P2860
P304
822-834.e7
P356
10.1053/J.GASTRO.2013.11.052
P407
P577
2013-12-06T00:00:00Z