Activation of Hedgehog signaling by the environmental toxicant arsenic may contribute to the etiology of arsenic-induced tumors.
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Arsenic trioxide inhibits human cancer cell growth and tumor development in mice by blocking Hedgehog/GLI pathwayArsenic antagonizes the Hedgehog pathway by preventing ciliary accumulation and reducing stability of the Gli2 transcriptional effectorHedgehog Cholesterolysis: Specialized Gatekeeper to Oncogenic SignalingThe mechanistic basis of arsenicosis: pathogenesis of skin cancerGenetic variations in the sonic hedgehog pathway affect clinical outcomes in non-muscle-invasive bladder cancerClinicopathological correlates of Gli1 expression in a population-based cohort of patients with newly diagnosed bladder cancerMutT Homolog 1 (MTH1) maintains multiple KRAS-driven pro-malignant pathways.Hedgehog pathway activation in human transitional cell carcinoma of the bladderGenes targeted by the Hedgehog-signaling pathway can be regulated by Estrogen related receptor βGLI3 Links Environmental Arsenic Exposure and Human Fetal Growth.Wild-Type U2AF1 Antagonizes the Splicing Program Characteristic of U2AF1-Mutant Tumors and Is Required for Cell Survival.Arsenic Attenuates GLI Signaling, Increasing or Decreasing its Transcriptional Program in a Context-Dependent Manner.Association between In Utero arsenic exposure, placental gene expression, and infant birth weight: a US birth cohort study.Hedgehog signaling regulates bladder cancer growth and tumorigenicityHedgehog-producing cancer cells respond to and require autocrine Hedgehog activity.The hedgehog processing pathway is required for NSCLC growth and survivalInhibition of WNT signaling attenuates self-renewal of SHH-subgroup medulloblastoma.Transcription Factor KLF5 Binds a Cyclin E1 Polymorphic Intronic Enhancer to Confer Increased Bladder Cancer RiskMTH1 expression is required for effective transformation by oncogenic HRAS.Direct binding of arsenic trioxide to AMPK and generation of inhibitory effects on acute myeloid leukemia precursors.Pyrvinium attenuates Hedgehog signaling downstream of smoothened.Inorganic arsenic can be potent granulotoxin in mammalian neutrophils in vitro.Urothelial Carcinoma Stem Cells: Current Concepts, Controversies, and Methods.
P2860
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P2860
Activation of Hedgehog signaling by the environmental toxicant arsenic may contribute to the etiology of arsenic-induced tumors.
description
2010 nî lūn-bûn
@nan
2010 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Activation of Hedgehog signali ...... ogy of arsenic-induced tumors.
@ast
Activation of Hedgehog signali ...... ogy of arsenic-induced tumors.
@en
type
label
Activation of Hedgehog signali ...... ogy of arsenic-induced tumors.
@ast
Activation of Hedgehog signali ...... ogy of arsenic-induced tumors.
@en
prefLabel
Activation of Hedgehog signali ...... ogy of arsenic-induced tumors.
@ast
Activation of Hedgehog signali ...... ogy of arsenic-induced tumors.
@en
P2093
P2860
P1433
P1476
Activation of Hedgehog signali ...... ogy of arsenic-induced tumors.
@en
P2093
Baolin Wang
Courtney D Kozul
David J Robbins
Dennis Liang Fei
James DiRenzo
Joshua W Hamilton
Julie A Gosse
Kathleen A Martin
Kendall E Black
P2860
P304
P356
10.1158/0008-5472.CAN-09-2898
P407
P577
2010-02-23T00:00:00Z