Loss of high-frequency glucose-induced Ca2+ oscillations in pancreatic islets correlates with impaired glucose tolerance in Trpm5-/- mice - sprookjes - yvandenbroek - TriplyDB

Loss of high-frequency glucose-induced Ca2+ oscillations in pancreatic islets correlates with impaired glucose tolerance in Trpm5-/- mice

Loss of high-frequency glucose-induced Ca2+ oscillations in pancreatic islets correlates with impaired glucose tolerance in Trpm5-/- mice

http://www.wikidata.org/entity/Q33740266

about

International Union of Basic and Clinical Pharmacology. LXXVI. Current progress in the mammalian TRP ion channel family Transient receptor potential (TRP) channels as drug targets for diseases of the digestive system TRP Channels as Therapeutic Targets in Diabetes and Obesity Nanomaterial-mediated Biosensors for Monitoring Glucose Transient receptor potential channels as therapeutic targets Expression of transient receptor potential ankyrin 1 (TRPA1) and its role in insulin release from rat pancreatic beta cells Transient receptor potential (TRP) channels: a clinical perspective DNA methylation signatures in cord blood associated with maternal gestational weight gain: results from the ALSPAC cohort TRPM5 regulates glucose-stimulated insulin secretion.Lipopolysaccharides directly decrease Ca2+ oscillations and the hyperpolarization-activated nonselective cation current If in immortalized HL-1 cardiomyocytes.Lack of TRPM2 impaired insulin secretion and glucose metabolisms in mice.TRP-ing down the path to insulin secretion.Nicotinic Acid Adenine Dinucleotide Phosphate (NAADP) and Endolysosomal Two-pore Channels Modulate Membrane Excitability and Stimulus-Secretion Coupling in Mouse Pancreatic β Cells.Steviol glycosides enhance pancreatic beta-cell function and taste sensation by potentiation of TRPM5 channel activity.A TRP channel contributes to insulin secretion by pancreatic β-cells.Molecular evidence for the loss of three basic tastes in penguins.Ionic mechanisms and Ca2+ dynamics underlying the glucose response of pancreatic β cells: a simulation study.TRP channels in the digestive system Activation of TRPM3 by a potent synthetic ligand reveals a role in peptide release.Redox Signal-mediated Enhancement of the Temperature Sensitivity of Transient Receptor Potential Melastatin 2 (TRPM2) Elevates Glucose-induced Insulin Secretion from Pancreatic Islets.Sweet taste receptor signaling in beta cells mediates fructose-induced potentiation of glucose-stimulated insulin secretion.Ablation of TRPM5 in Mice Results in Reduced Body Weight Gain and Improved Glucose Tolerance and Protects from Excessive Consumption of Sweet Palatable Food when Fed High Caloric Diets Insm1 cooperates with Neurod1 and Foxa2 to maintain mature pancreatic β-cell function Bursting and calcium oscillations in pancreatic beta-cells: specific pacemakers for specific mechanisms.Sugar-induced cephalic-phase insulin release is mediated by a T1r2+T1r3-independent taste transduction pathway in mice The role of T1r3 and Trpm5 in carbohydrate-induced obesity in mice Type 2 Diabetes-Associated K+ Channel TALK-1 Modulates β-Cell Electrical Excitability, Second-Phase Insulin Secretion, and Glucose Homeostasis GLP-1 stimulates insulin secretion by PKC-dependent TRPM4 and TRPM5 activation.TRPs in taste and chemesthesis.Store-operated Ca2+ Entry Mediated by Orai1 and TRPC1 Participates to Insulin Secretion in Rat β-Cells.A computational systems analysis of factors regulating α cell glucagon secretion.RNA-sequencing of WFS1-deficient pancreatic islets.Ion channels and regulation of insulin secretion in human β-cells: a computational systems analysis TRPM5-mediated calcium uptake regulates mucin secretion from human colon goblet cells.Catecholamines Facilitate Fuel Expenditure and Protect Against Obesity via a Novel Network of the Gut-Brain Axis in Transcription Factor Skn-1-deficient Mice.Enhanced insulin clearance in mice lacking TRPM8 channels.Chemosensors in the nose: guardians of the airways Extracellular zinc ion regulates transient receptor potential melastatin 5 (TRPM5) channel activation through its interaction with a pore loop domain.Insulin downregulates the expression of the Ca2+-activated nonselective cation channel TRPM5 in pancreatic islets from leptin-deficient mouse models.The role of transient receptor potential cation channels in Ca2+ signaling

P2860

Q24623493-D259284D-CC5A-401D-B84E-6FC34CE4DEA9 Q24627020-77D45541-015A-40A6-84BA-12657240FA69 Q26739958-75E800AF-F3F1-47E2-B4B4-8E48CF9BF134 Q26866355-1A2468C1-3F83-4381-9944-735BA081960B Q28244558-EB36D489-801E-4DBC-9BDA-508E9A277F7A Q28570050-FD9CAA30-FE74-4A68-B1AC-35291D64D432 Q33562143-4A4D33B2-F671-4110-BCF9-7F3A689B35FA Q33938865-E5A09708-5FDC-43BA-99DF-9BE9D819C681 Q34110282-70E559F2-E6FE-4017-9944-A893294EE630 Q34149775-D8F9BB4D-A310-4135-A7AC-667AAB9B4A81 Q34448620-93AF3789-95C1-4A4F-954E-AA6084461CA9 Q34448713-79ABC811-4050-4180-ACE3-2C947B5BC081 Q34483914-7468FA4C-B8E4-4A33-A8CB-92B7AB644629 Q34554463-7287F105-3178-4DAD-BABC-99249B4C60D0 Q34706903-8EE30CA6-88E9-4747-A438-1390ACD03326 Q35097878-3EDD410A-8FD0-4327-9581-BAF8964E3E35 Q35102159-161A10AF-C6F5-4CA9-A4C8-457EB864761B Q35177823-CA97D0EE-B897-4F1D-9714-B193E9C9A1D4 Q35212579-C89CE658-D742-4F49-81BA-2E86AFFD5F82 Q35583234-EF53A788-E3DB-45EA-9FA1-9E62732908E0 Q35779299-E5D5684F-9FB1-4A54-B456-6B6F83DAADD4 Q35784531-0A14B086-5496-4727-B2BE-5AEBB0B546A0 Q35819673-6627422A-06E2-4C7A-B743-7A82DF1F382E Q36093228-CE835337-5C97-46B0-99E2-F3D1A32158B3 Q36114147-C2903E86-BED6-4DF2-BDBC-417B3818296A Q36131196-57A26A6D-7E47-434F-ACDB-51BB821631B8 Q36186289-02B9480F-FA01-4CF8-9F35-460D91EDA724 Q36335898-DF4AB9F1-1C76-4A61-A5D4-2AD0F0E2B08C Q36341123-021B24D8-4D7E-404E-AAF1-D9FD130D1F50 Q36381961-A848E1E7-0683-447B-AFC4-B0907882C4B8 Q36394674-7ED65DE0-D806-486D-AD93-6BE0A80CD67C Q36797423-C9BF49EF-0BD9-4A12-8E7C-499C3C369144 Q36870356-BD383D52-EDA1-453E-81BB-740EE049B85D Q36887004-240185BE-1D27-4471-A1A0-9D5D53CD5D85 Q37034803-17CB54CD-CAA9-4F3E-B0C6-23B31417240E Q37051102-6B17E7F3-2540-4487-AA47-D32B8F6C5F33 Q37078683-B92B7D77-7235-4777-B6FA-45A137FC3462 Q37151033-299D35F9-3C4C-4A23-A6F8-1EEE45B30A3D Q37592008-2A9635B2-94C2-4D74-9247-6AE675C165CF Q37791280-1BBA04FE-441F-4008-9D76-B94A2907DF87

P2860

Loss of high-frequency glucose-induced Ca2+ oscillations in pancreatic islets correlates with impaired glucose tolerance in Trpm5-/- mice

http://www.wikidata.org/entity/Q33740266

description

2010 nî lūn-bûn

@nan

2010 թուականի Մարտին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի մարտին հրատարակված գիտական հոդված

@hy

2010年の論文

@ja

2010年論文

@yue

2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

Loss of high-frequency glucose ...... ose tolerance in Trpm5-/- mice

@ast

Loss of high-frequency glucose ...... ose tolerance in Trpm5-/- mice

@en

type

label

Loss of high-frequency glucose ...... ose tolerance in Trpm5-/- mice

@ast

Loss of high-frequency glucose ...... ose tolerance in Trpm5-/- mice

@en

prefLabel

Loss of high-frequency glucose ...... ose tolerance in Trpm5-/- mice

@ast

Loss of high-frequency glucose ...... ose tolerance in Trpm5-/- mice

@en

P1433

Q33740266-A219D2C7-A794-42E4-A5B0-2A02F509A89A

P1476

Q33740266-AF746097-BBAD-4B33-BAA2-80A6C3C87351

P2093

Q33740266-1F599AF8-070E-43F7-A6F8-5809652FDC50

Q33740266-3990806B-2DE8-42D0-9A10-D8A6D1159C63

Q33740266-4F7271F2-FD3B-484F-904F-C456FA18FB4C

Q33740266-90C5311B-946D-4B4A-8779-D46EC943FC3F

Q33740266-AD96AC85-1E61-46D1-A5B1-6457A7478606

Q33740266-C46408BA-0070-4A19-AE1C-426E20749D41

Q33740266-C9D15EC2-8F92-4A3D-8BBC-376328417F67

Q33740266-CE5E8C46-52E9-4498-BB76-1C1CEDA93960

P2860

Q33740266-002F29B5-EDFD-47F2-8698-FA11E9156325

Q33740266-06387C41-9C37-4300-9F14-1DD905462BF6

Q33740266-19BE5F8B-9DBB-4B88-89DA-12C111B9A3D7

Q33740266-243F2A38-7EE9-485F-910E-5112CE3076AE

Q33740266-2740D092-D061-42E5-A76F-9EB38830CB49

Q33740266-2972ECB3-6754-4B18-BC74-65AE0FD65D97

Q33740266-2FAAD857-A5CD-478A-AF01-97C131C50A9E

Q33740266-3BDB7915-FE88-4981-882E-859A097F7C93

Q33740266-3FE903DB-08C3-4D5F-A134-F213F152BD7B

Q33740266-439668C4-9153-4521-A1A5-BECBBA362D2C

P304

Q33740266-C8158D9F-DB4F-4D2F-BEE4-2D4ADA5BB4A1

P31

Q33740266-6DA327F3-545B-4ECB-ACAB-E615A4B567DE

P356

Q33740266-62D9F673-B531-4C3E-97FD-89A1F5B0A1E9

P407

Q33740266-AE0A12DE-51E6-4A46-B5C5-0130276AFD6B

P433

Q33740266-FD0F7319-F1D0-4CA8-A3E9-2F8F57F974B4

P478

Q33740266-5C266DD0-4192-4311-9B17-C6CC9B4216F3

P50

Q33740266-010F0191-1D24-434B-959B-827721F38A59

Q33740266-1C75F48B-CC55-4D52-9AF6-7396C138DAD0

Q33740266-21A0C37E-844D-4BF9-8E42-2D430B3BA0AB

Q33740266-2DFB215C-E0DD-41FA-9339-0BD90E94ED04

Q33740266-68D5FC84-4DF9-49A3-95E3-39ABE444FBEF

Q33740266-CC6A01D1-2F2C-4EDF-9B57-B3EB4EF8DC33

Q33740266-FFF1BA8D-A063-4FB1-AEC0-CCEA1AE377D7

P577

Q33740266-4B387B49-3520-4245-9050-61FFD77326B6

P5875

Q33740266-93A4A1A0-CFBD-4093-9D5E-90EE31D31632

P698

Q33740266-15BB0DF5-C176-43B4-B240-12D7CB1B53D5

P921

Q33740266-3a91cf60-b305-4b34-b204-c58118f0266e

P932

Q33740266-E4D3B6D6-4EED-46A6-BC61-24136006D3C8

P356

PNAS.0913107107

P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

Loss of high-frequency glucose ...... ose tolerance in Trpm5-/- mice

@en

P2093

Andrei Segal

http://www.w3.org/2001/XMLSchema#string

Anica Schraenen

http://www.w3.org/2001/XMLSchema#string

Barbara Colsoul

http://www.w3.org/2001/XMLSchema#string

Frans C Schuit

http://www.w3.org/2001/XMLSchema#string

Katleen Lemaire

http://www.w3.org/2001/XMLSchema#string

Patrick Gilon

http://www.w3.org/2001/XMLSchema#string

Roel Quintens

http://www.w3.org/2001/XMLSchema#string

Zaza Kokrashvili

http://www.w3.org/2001/XMLSchema#string

P2860

Oscillations, intercellular coupling, and insulin secretion in pancreatic beta cells.

Identification and characterization of MTR1, a novel gene with homology to melastatin (MLSN1) and the trp gene family located in the BWS-WT2 critical region on chromosome 11p15.5 and showing allele-specific expression

The NALCN ion channel is activated by M3 muscarinic receptors in a pancreatic beta-cell line

G-protein-coupled receptors and islet function-implications for treatment of type 2 diabetes.

Coding of sweet, bitter, and umami tastes: different receptor cells sharing similar signaling pathways

Electrophysiology of the pancreatic beta-cell

Transient receptor potential cation channels in disease

TRPM4 controls insulin secretion in pancreatic beta-cells

Voltage dependence of the Ca2+-activated cation channel TRPM4

TRPM4 is a Ca2+-activated nonselective cation channel mediating cell membrane depolarization

P304

5208-5213

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1073/PNAS.0913107107

http://www.w3.org/2001/XMLSchema#string

P407

P433

11

http://www.w3.org/2001/XMLSchema#string

P478

107

http://www.w3.org/2001/XMLSchema#string

P50

Robert Margolskee

Leentje Van Lommel

Grzegorz Owsianik

P577

2010-03-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

41656822

http://www.w3.org/2001/XMLSchema#string

P698

20194741

http://www.w3.org/2001/XMLSchema#string

P921

P932

2841940

http://www.w3.org/2001/XMLSchema#string