Excision of titin's cardiac PEVK spring element abolishes PKCalpha-induced increases in myocardial stiffness
about
Titin-based tension in the cardiac sarcomere: molecular origin and physiological adaptationsHeart failure with preserved ejection fractionWhat global diastolic function is, what it is not, and how to measure itPhysiologic basis and pathophysiologic implications of the diastolic properties of the cardiac muscleContribution of titin and extracellular matrix to passive pressure and measurement of sarcomere length in the mouse left ventricle.The giant protein titin: a regulatory node that integrates myocyte signaling pathways.Cardiac titin and heart disease.Increased myocardial stiffness due to cardiac titin isoform switching in a mouse model of volume overload limits eccentric remodelingTitin based viscosity in ventricular physiology: an integrative investigation of PEVK-actin interactions.Hyperphosphorylation of mouse cardiac titin contributes to transverse aortic constriction-induced diastolic dysfunctionMyocardial stiffness in patients with heart failure and a preserved ejection fraction: contributions of collagen and titinTitin-actin interaction: PEVK-actin-based viscosity in a large animalCell-intrinsic functional effects of the α-cardiac myosin Arg-403-Gln mutation in familial hypertrophic cardiomyopathy.The multifunctional Ca(2+)/calmodulin-dependent protein kinase II delta (CaMKIIδ) phosphorylates cardiac titin's spring elements.Titin is a major human disease gene.Right Ventricular Myocardial Stiffness in Experimental Pulmonary Arterial Hypertension: Relative Contribution of Fibrosis and Myofibril Stiffness.Shortening of the elastic tandem immunoglobulin segment of titin leads to diastolic dysfunction.Removal of immunoglobulin-like domains from titin's spring segment alters titin splicing in mouse skeletal muscle and causes myopathy.Tuning the molecular giant titin through phosphorylation: role in health and disease.Tampering with springs: phosphorylation of titin affecting the mechanical function of cardiomyocytes.Experimentally Increasing the Compliance of Titin Through RNA Binding Motif-20 (RBM20) Inhibition Improves Diastolic Function In a Mouse Model of Heart Failure With Preserved Ejection Fraction.Activation and stretch-induced passive force enhancement--are you pulling my chain? Focus on "Regulation of muscle force in the absence of actin-myosin-based cross-bridge interaction"Force enhancement after stretch in mammalian muscle fiber: no evidence of cross-bridge involvement.The link between exercise and titin passive stiffness.The multiple roles of titin in muscle contraction and force production.
P2860
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P2860
Excision of titin's cardiac PEVK spring element abolishes PKCalpha-induced increases in myocardial stiffness
description
2009 nî lūn-bûn
@nan
2009 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Excision of titin's cardiac PE ...... reases in myocardial stiffness
@ast
Excision of titin's cardiac PE ...... reases in myocardial stiffness
@en
type
label
Excision of titin's cardiac PE ...... reases in myocardial stiffness
@ast
Excision of titin's cardiac PE ...... reases in myocardial stiffness
@en
prefLabel
Excision of titin's cardiac PE ...... reases in myocardial stiffness
@ast
Excision of titin's cardiac PE ...... reases in myocardial stiffness
@en
P2093
P2860
P1476
Excision of titin's cardiac PE ...... reases in myocardial stiffness
@en
P2093
Bryan D Hudson
Carlos G Hidalgo
Henk L Granzier
P2860
P304
P356
10.1016/J.YJMCC.2009.12.006
P577
2009-12-21T00:00:00Z