about
Reeler/Disabled-like disruption of neuronal migration in knockout mice lacking the VLDL receptor and ApoE receptor 2Interactions of the low density lipoprotein receptor gene family with cytosolic adaptor and scaffold proteins suggest diverse biological functions in cellular communication and signal transductionThe complete gene sequence of titin, expression of an unusual approximately 700-kDa titin isoform, and its interaction with obscurin identify a novel Z-line to I-band linking systemRBM20, a gene for hereditary cardiomyopathy, regulates titin splicingNeuronal sorting protein-related receptor sorLA/LR11 regulates processing of the amyloid precursor protein.Inducible inactivation of hepatic LRP gene by cre-mediated recombination confirms role of LRP in clearance of chylomicron remnantsPodocyte-Specific Deletion of Murine CXADR Does Not Impair Podocyte Development, Function or Stress ResponseCoxsackie and adenovirus receptor is a modifier of cardiac conduction and arrhythmia vulnerability in the setting of myocardial ischemiaThe reelin receptor ApoER2 recruits JNK-interacting proteins-1 and -2Platelet-derived growth factor mediates tyrosine phosphorylation of the cytoplasmic domain of the low Density lipoprotein receptor-related protein in caveolaeSmooth muscle-selective deletion of guanylyl cyclase-A prevents the acute but not chronic effects of ANP on blood pressureInduction and myofibrillar targeting of CARP, and suppression of the Nkx2.5 pathway in the MDM mouse with impaired titin-based signalingTargeted deletion of titin N2B region leads to diastolic dysfunction and cardiac atrophyM line-deficient titin causes cardiac lethality through impaired maturation of the sarcomereNormal blood pressure and plasma renin activity in mice lacking the renin-binding protein, a cellular renin inhibitorAxial tubule junctions control rapid calcium signaling in atriaExcision of titin's cardiac PEVK spring element abolishes PKCalpha-induced increases in myocardial stiffnessCellular signalling by lipoprotein receptors.RNA-binding protein RBM20 represses splicing to orchestrate cardiac pre-mRNA processing.Calcium sensitivity and the Frank-Starling mechanism of the heart are increased in titin N2B region-deficient miceDeletion of the titin N2B region accelerates myofibrillar force development but does not alter relaxation kineticsLRP: role in vascular wall integrity and protection from atherosclerosis.Moderate inappropriately high aldosterone/NaCl constellation in mice: cardiovascular effects and the role of cardiovascular epidermal growth factor receptor.Titin based viscosity in ventricular physiology: an integrative investigation of PEVK-actin interactions.Titin visualization in real time reveals an unexpected level of mobility within and between sarcomeresMechanics on myocardium deficient in the N2B region of titin: the cardiac-unique spring element improves efficiency of the cardiac cycle.LRP and PDGF signaling: a pathway to atherosclerosis.Integrated allelic, transcriptional, and phenomic dissection of the cardiac effects of titin truncations in health and diseaseAltered contractility of skeletal muscle in mice deficient in titin's M-band region.Calcium sensitivity and myofilament lattice structure in titin N2B KO mice.The tight junction protein CAR regulates cardiac conduction and cell-cell communication.CAR-diology--a virus receptor in the healthy and diseased heart.Recessive TTN truncating mutations define novel forms of core myopathy with heart disease.Interspecies differences in virus uptake versus cardiac function of the coxsackievirus and adenovirus receptor.Truncation of titin's elastic PEVK region leads to cardiomyopathy with diastolic dysfunction.Enhancement of the endothelial NO synthase attenuates experimental diastolic heart failure.A proteome map of murine heart and skeletal muscle.Cardiac hypertrophy and reduced contractility in hearts deficient in the titin kinase region.The Src homology and collagen A (ShcA) adaptor protein is required for the spatial organization of the costamere/Z-disk network during heart development.Role of smooth muscle cGMP/cGKI signaling in murine vascular restenosis.
P50
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P50
description
hulumtues
@sq
onderzoeker
@nl
researcher
@en
ricercatore
@it
հետազոտող
@hy
name
Michael Gotthardt
@ast
Michael Gotthardt
@en
Michael Gotthardt
@es
Michael Gotthardt
@nl
Michael Gotthardt
@sl
type
label
Michael Gotthardt
@ast
Michael Gotthardt
@en
Michael Gotthardt
@es
Michael Gotthardt
@nl
Michael Gotthardt
@sl
prefLabel
Michael Gotthardt
@ast
Michael Gotthardt
@en
Michael Gotthardt
@es
Michael Gotthardt
@nl
Michael Gotthardt
@sl
P214
P106
P21
P214
P31
P496
0000-0003-1788-3172
P734
P735
P7859
lccn-no2002109946