Diversity in the neural circuitry of cold sensing revealed by genetic axonal labeling of transient receptor potential melastatin 8 neurons - sprookjes - yvandenbroek - TriplyDB

Diversity in the neural circuitry of cold sensing revealed by genetic axonal labeling of transient receptor potential melastatin 8 neurons

Diversity in the neural circuitry of cold sensing revealed by genetic axonal labeling of transient receptor potential melastatin 8 neurons

http://www.wikidata.org/entity/Q33903991

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The functional and anatomical dissection of somatosensory subpopulations using mouse genetics Spinal cord thermosensitivity: An afferent phenomenon?TRPA1 is a component of the nociceptive response to CO2 Ion channel profile of TRPM8 cold receptors reveals a role of TASK-3 potassium channels in thermosensation.TRPA1 acts as a cold sensor in vitro and in vivo.The coding of temperature in the Drosophila brain TRPM8 is a neuronal osmosensor that regulates eye blinking in mice.Function and postnatal changes of dural afferent fibers expressing TRPM8 channels.Cutaneous TRPM8-expressing sensory afferents are a small population of neurons with unique firing properties.Cooling-sensitive TRPM8 is thermostat of skin temperature against cooling.Threshold and rate sensitivity of low-threshold thermal nociception.Sensing hot and cold with TRP channels.The development of peripheral cold neural circuits based on TRPM8 expression.Menthol response and adaptation in nociceptive-like and nonnociceptive-like neurons: role of protein kinases.Labeled lines meet and talk: population coding of somatic sensations.CGRPα-expressing sensory neurons respond to stimuli that evoke sensations of pain and itch.A review of topical high-concentration L-menthol as a translational model of cold allodynia and hyperalgesia.Anti-hyperalgesic effects of a novel TRPM8 agonist in neuropathic rats: a comparison with topical menthol.The modality-specific contribution of peptidergic and non-peptidergic nociceptors is manifest at the level of dorsal horn nociresponsive neurons.Transient receptor potential channels: targeting pain at the source.Scraping through the ice: uncovering the role of TRPM8 in cold transduction Central connectivity of transient receptor potential melastatin 8-expressing axons in the brain stem and spinal dorsal horn AMG2850, a potent and selective TRPM8 antagonist, is not effective in rat models of inflammatory mechanical hypersensitivity and neuropathic tactile allodynia TRPM8 on mucosal sensory nerves regulates colitogenic responses by innate immune cells via CGRP Structural basis for serotonergic regulation of neural circuits in the mouse olfactory bulb.Robo2 determines subtype-specific axonal projections of trigeminal sensory neurons.Regulation of TRPM8 channel activity KCNQ channels in nociceptive cold-sensing trigeminal ganglion neurons as therapeutic targets for treating orofacial cold hyperalgesia.Molecular and cellular mechanisms that initiate pain and itch.Chemosensory properties of the trigeminal system.Structural basis for cholinergic regulation of neural circuits in the mouse olfactory bulb.TRPM8 ion channel is aberrantly expressed and required for preventing replicative senescence in pancreatic adenocarcinoma: potential role of TRPM8 as a biomarker and target Spatial distribution of synapses on tyrosine hydroxylase-expressing juxtaglomerular cells in the mouse olfactory glomerulus.Cellular permeation of large molecules mediated by TRPM8 channels.TRPs in taste and chemesthesis.Sensory discrimination between innocuous and noxious cold by TRPM8-expressing DRG neurons of rats.Quantitative characterization reveals three types of dry-sensitive corneal afferents: pattern of discharge, receptive field, and thermal and chemical sensitivity.Pharmacological blockade of the cold receptor TRPM8 attenuates autonomic and behavioral cold defenses and decreases deep body temperature.The molecular and cellular basis of cold sensation.TRPM8 mechanism of autonomic nerve response to cold in respiratory airway.

P2860

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P2860

Diversity in the neural circuitry of cold sensing revealed by genetic axonal labeling of transient receptor potential melastatin 8 neurons

http://www.wikidata.org/entity/Q33903991

description

2007 nî lūn-bûn

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2007 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2007 թվականի դեկտեմբերին հրատարակված գիտական հոդված

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2007年の論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年论文

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name

Diversity in the neural circui ...... potential melastatin 8 neurons

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Diversity in the neural circui ...... potential melastatin 8 neurons

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Diversity in the neural circui ...... potential melastatin 8 neurons

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Diversity in the neural circui ...... potential melastatin 8 neurons

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Diversity in the neural circui ...... potential melastatin 8 neurons

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Diversity in the neural circui ...... potential melastatin 8 neurons

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JNEUROSCI.4578-07.2007

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Journal of Neuroscience

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Diversity in the neural circui ...... potential melastatin 8 neurons

@en

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David D McKemy

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Emily R Liman

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James Teng

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Richard L Daniels

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Wendy Knowlton

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Yoshio Takashima

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P2860

Mice left out in the cold: commentary on the phenotype of TRPM8-nulls

How cold is it? TRPM8 and TRPA1 in the molecular logic of cold sensation.

Pain mechanisms: labeled lines versus convergence in central processing

Molecular mechanisms of nociception

The menthol receptor TRPM8 is the principal detector of environmental cold

TRPM8 is required for cold sensation in mice

ANKTM1, a TRP-like channel expressed in nociceptive neurons, is activated by cold temperatures

A TRP channel that senses cold stimuli and menthol

Identification of a cold receptor reveals a general role for TRP channels in thermosensation

Attenuated cold sensitivity in TRPM8 null mice

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14147-14157

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10.1523/JNEUROSCI.4578-07.2007

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51

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2883248

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