Discontinuous, conserved neutralization epitopes overlapping the CD4-binding region of human immunodeficiency virus type 1 gp120 envelope glycoprotein
about
Pathogenesis of human immunodeficiency virus infectionHyperglycosylated mutants of human immunodeficiency virus (HIV) type 1 monomeric gp120 as novel antigens for HIV vaccine designA novel human T-leukemia virus type 1 cell-to-cell transmission assay permits definition of SU glycoprotein amino acids important for infectivityAntibodies to Envelope Glycoprotein of Dengue Virus during the Natural Course of Infection Are Predominantly Cross-Reactive and Recognize Epitopes Containing Highly Conserved Residues at the Fusion Loop of Domain IICrystal Structure of the Neutralizing Llama VHH D7 and Its Mode of HIV-1 gp120 InteractionFine mapping of the interaction of neutralizing and nonneutralizing monoclonal antibodies with the CD4 binding site of human immunodeficiency virus type 1 gp120.Anti-human immunodeficiency virus type 1 activity of an oligocationic compound mediated via gp120 V3 interactionsCharacterization of neutralizing monoclonal antibodies to linear and conformation-dependent epitopes within the first and second variable domains of human immunodeficiency virus type 1 gp120Human monoclonal antibody 2G12 defines a distinctive neutralization epitope on the gp120 glycoprotein of human immunodeficiency virus type 1Broadly cross-reactive HIV-1-neutralizing human monoclonal Fab selected for binding to gp120-CD4-CCR5 complexes.A novel human antibody against human immunodeficiency virus type 1 gp120 is V1, V2, and V3 loop dependent and helps delimit the epitope of the broadly neutralizing antibody immunoglobulin G1 b12.Identification and characterization of a new cross-reactive human immunodeficiency virus type 1-neutralizing human monoclonal antibody.A strategy for eliciting antibodies against cryptic, conserved, conformationally dependent epitopes of HIV envelope glycoproteinInfluence of novel CD4 binding-defective HIV-1 envelope glycoprotein immunogens on neutralizing antibody and T-cell responses in nonhuman primatesChanges in human immunodeficiency virus type 1 envelope glycoproteins responsible for the pathogenicity of a multiply passaged simian-human immunodeficiency virus (SHIV-HXBc2)Influence of disulfide-stabilized structure on the specificity of helper T-cell and antibody responses to HIV envelope glycoprotein gp120Mutations in both gp120 and gp41 are responsible for the broad neutralization resistance of variant human immunodeficiency virus type 1 MN to antibodies directed at V3 and non-V3 epitopes.Characterization of simian-human immunodeficiency virus envelope glycoprotein epitopes recognized by neutralizing antibodies from infected monkeysReevaluation of amino acid variability of the human immunodeficiency virus type 1 gp120 envelope glycoprotein and prediction of new discontinuous epitopesCross-subtype neutralizing antibodies induced in baboons by a subtype E gp120 immunogen based on an R5 primary human immunodeficiency virus type 1 envelope.Determinants of neutralization resistance in the envelope glycoproteins of a simian-human immunodeficiency virus passaged in vivo.Improved elicitation of neutralizing antibodies against primary human immunodeficiency viruses by soluble stabilized envelope glycoprotein trimers.Envelope glycoprotein determinants of neutralization resistance in a simian-human immunodeficiency virus (SHIV-HXBc2P 3.2) derived by passage in monkeys.Structure of the Fab fragment of F105, a broadly reactive anti-human immunodeficiency virus (HIV) antibody that recognizes the CD4 binding site of HIV type 1 gp120.Analysis of epitopes on dengue virus envelope protein recognized by monoclonal antibodies and polyclonal human sera by a high throughput assayV3-specific neutralizing antibodies in sera from HIV-1 gp160-immunized volunteers block virus fusion and act synergistically with human monoclonal antibody to the conformation-dependent CD4 binding site of gp120. NIH-NIAID AIDS Vaccine Clinical TriaVertical Transmission of HIV-1. Correlation with maternal viral load and plasma levels of CD4 binding site anti-gp120 antibodiesMutagenic stabilization and/or disruption of a CD4-bound state reveals distinct conformations of the human immunodeficiency virus type 1 gp120 envelope glycoproteinCD4 binding site antibodies inhibit human immunodeficiency virus gp120 envelope glycoprotein interaction with CCR5Rapid conformational epitope mapping of anti-gp120 antibodies with a designed mutant panel displayed on yeastA single injection of recombinant measles virus vaccines expressing human immunodeficiency virus (HIV) type 1 clade B envelope glycoproteins induces neutralizing antibodies and cellular immune responses to HIV.Neutralizing antibody responses in macaques induced by human immunodeficiency virus type 1 monovalent or trivalent envelope glycoproteins.An HIV-1 envelope immunogen with W427S mutation in CD4 binding site induced more T follicular helper memory cells and reduced non-specific antibody responses.Allosteric induction of the CD4-bound conformation of HIV-1 Gp120.Multiple interactions across the surface of the gp120 core structure determine the global neutralization resistance phenotype of human immunodeficiency virus type 1Neutralization of divergent human immunodeficiency virus type 1 variants and primary isolates by IAM-41-2F5, an anti-gp41 human monoclonal antibody.Combined intra- and extracellular immunization against human immunodeficiency virus type 1 infection with a human anti-gp120 antibody.The highly conserved aspartic acid residue between hypervariable regions 1 and 2 of human immunodeficiency virus type 1 gp120 is important for early stages of virus replication.Regions required for CD4 binding in the external glycoprotein gp120 of simian immunodeficiency virusAdaptation of human immunodeficiency virus type 1 to cells expressing a binding-deficient CD4 mutant (lysine 46 to aspartic acid)
P2860
Q24634681-93181A10-EB6C-459D-A021-7E582134A250Q24679395-30474651-AB8D-40F2-92B9-9A99CDF202D4Q27480768-5AA090D6-A3CF-4124-BA13-0C407E2173E7Q27486409-C2FC1AA6-C47A-43C8-9F23-CFE3732CF222Q27661588-274BFA2E-16B2-4DD0-9591-00555CF79C50Q28217208-15C00AB2-0A36-493C-A6FF-B0FE11B50C63Q28378840-FB340F42-9342-493E-BE72-A3FD8DD41C0DQ28646835-C74C2A19-AE80-478B-8B65-10E0FF2C2F1AQ29619512-28BA0643-FB02-4F2F-96DA-41DBFFB899F2Q30706865-4BDB1A8D-8908-402F-B07C-77C1F6E74547Q31143293-F6E90F2B-1A28-43B5-8779-952A194A1C6DQ33205911-37424C33-76F1-4FA8-BC34-51AAF583F212Q33522232-02E1F652-F16E-4392-B191-6CF7E7FA63E8Q33614605-338CE4D9-5872-4A9E-A90B-2341F64780DAQ33640139-2A8F40B7-F0FF-40E3-B0CD-3AC585F3D0A7Q33725711-6F299EBD-0BDB-40A4-8867-258E65BE2F06Q33783763-3ED3E53D-242D-4383-93E6-5FB7E5030F5FQ33785114-D8A15A7F-03E7-4F95-B993-5FED7C16CB2CQ33803939-99B0B45E-48B4-4E77-A74E-DEA293ECE91FQ33813526-AC30AB76-AF1C-4DAF-B44B-03B95B2D8019Q33821658-621905D0-D969-488C-9B7A-08290BB43352Q33836042-31976796-D78D-4EBF-924A-E93146C8F5B8Q33839485-C750E1ED-B047-4EED-B608-FF74BEB416B8Q34045535-62E02CD9-E406-481A-B806-C860B63FDA62Q34123956-6F8369E0-5084-44E8-BBCB-17A07BE07F4DQ34171212-1388EED3-C3FB-4F42-8F30-A8D2B362EBABQ34201595-282FF760-A3E4-4D89-812B-C2F1DADD867FQ34347265-15B48652-F3A2-4414-BE74-111FE93357F0Q34462299-46722443-2D44-4231-A59B-7CB132A15176Q34480254-E159DC6C-C27E-4CF9-8C59-E782305D9DB5Q34552313-BCCF683E-621C-4273-98E5-ED6B50190E77Q34637968-9C33CFA7-CF22-4A11-AFC1-AC5F536E65E4Q34784825-642A5A72-7542-4C74-B18E-B274D3BE2816Q35058860-C3010746-A963-41B6-9B28-7B4A77387D6EQ35105006-4922A963-EF89-4F2E-B5B5-6D2608EC4309Q35170702-F5F86D3C-49D3-4C5C-BE0D-FC372F67F197Q35542605-139B4F6E-586E-498F-B629-A83DF713C084Q35830393-D4BCD68C-378D-4D3B-8DA0-F57D80A9C795Q35833044-76EA1915-46C5-441A-85E1-3C972B5B3BE0Q35838613-E8F45B96-33E6-4F64-96C7-6E0319A12218
P2860
Discontinuous, conserved neutralization epitopes overlapping the CD4-binding region of human immunodeficiency virus type 1 gp120 envelope glycoprotein
description
1992 nî lūn-bûn
@nan
1992 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1992 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
name
Discontinuous, conserved neutr ...... 1 gp120 envelope glycoprotein
@ast
Discontinuous, conserved neutr ...... 1 gp120 envelope glycoprotein
@en
type
label
Discontinuous, conserved neutr ...... 1 gp120 envelope glycoprotein
@ast
Discontinuous, conserved neutr ...... 1 gp120 envelope glycoprotein
@en
prefLabel
Discontinuous, conserved neutr ...... 1 gp120 envelope glycoprotein
@ast
Discontinuous, conserved neutr ...... 1 gp120 envelope glycoprotein
@en
P2093
P2860
P1433
P1476
Discontinuous, conserved neutr ...... 1 gp120 envelope glycoprotein
@en
P2093
P2860
P304
P407
P577
1992-09-01T00:00:00Z