Gain-of-function mutations in the tumor suppressor gene p53.
about
Expression of full-length p53 and its isoform Deltap53 in breast carcinomas in relation to mutation status and clinical parametersMolecular biology of lung cancer: clinical implicationsUpdated overview of current biomarkers in head and neck carcinomaOccurrence of multipolar mitoses and association with Aurora-A/-B kinases and p53 mutations in aneuploid esophageal carcinoma cellsGermline p53 mutations in a cohort with childhood sarcoma: sex differences in cancer riskA p53 genetic polymorphism of gastric cancer: difference between early gastric cancer and advanced gastric cancer.High-level expression of wild-type p53 in melanoma cells is frequently associated with inactivity in p53 reporter gene assaysPharmacogenetics research on chemotherapy resistance in colorectal cancer over the last 20 yearsMutations in APC, Kirsten-ras, and p53--alternative genetic pathways to colorectal cancer.Androgen receptor signaling and mutations in prostate cancerThe role of p53, PCNA and Ki-67 as outcome predictors in the treatment of laryngeal cancerp53 in head and neck cancer: functional consequences and environmental implications of TP53 mutations.Preferential binding of hot spot mutant p53 proteins to supercoiled DNA in vitro and in cells.INGN-225: a dendritic cell-based p53 vaccine (Ad.p53-DC) in small cell lung cancer: observed association between immune response and enhanced chemotherapy effect.Daple is a novel non-receptor GEF required for trimeric G protein activation in Wnt signaling.The MLL partial tandem duplication: evidence for recessive gain-of-function in acute myeloid leukemia identifies a novel patient subgroup for molecular-targeted therapyImmunotherapy treatments for small-cell lung cancer: past, present and future.Small-Molecule NSC59984 Restores p53 Pathway Signaling and Antitumor Effects against Colorectal Cancer via p73 Activation and Degradation of Mutant p53.Contextualizing the Genes Altered in Bladder Neoplasms in Pediatric andTeen Patients Allows Identifying Two Main Classes of Biological ProcessesInvolved and New Potential Therapeutic TargetsRING finger protein 31 promotes p53 degradation in breast cancer cells.An extended set of yeast-based functional assays accurately identifies human disease mutations.Structural profiles of TP53 gene mutations predict clinical outcome in diffuse large B-cell lymphoma: an international collaborative study.p53 Mutation: Critical Mediator of Therapy Resistance against Tumor Microenvironment.Vulnerabilities of mutant SWI/SNF complexes in cancer.Curcumol triggers apoptosis of p53 mutant triple-negative human breast cancer MDA-MB 231 cells via activation of p73 and PUMA.Subtype-Specific Radiation Response and Therapeutic Effect of FAS Death Receptor Modulation in Human Breast Cancer.ID4 regulates transcriptional activity of wild type and mutant p53 via K373 acetylationCombining p53 stabilizers with metformin induces synergistic apoptosis through regulation of energy metabolism in castration-resistant prostate cancer.Loss of p53 enhances the function of the endoplasmic reticulum through activation of the IRE1α/XBP1 pathway.Mutant p53(R175H) upregulates Twist1 expression and promotes epithelial-mesenchymal transition in immortalized prostate cells.E2F4 and ribonucleotide reductase mediate S-phase arrest in colon cancer cells treated with chlorophyllin.Comprehensive analysis of differential co-expression patterns reveal transcriptional dysregulation mechanism and identify novel prognostic lncRNAs in esophageal squamous cell carcinoma.New perspectives of cobalt tris(bipyridine) system: anti-cancer effect and its collateral sensitivity towards multidrug-resistant (MDR) cancers.Expression of a mutant p53 results in an age-related demographic shift in spontaneous lung tumor formation in transgenic mice.Biomarkers in advanced larynx cancer.Expression of p53 and Bcl-xL as predictive markers for larynx preservation in advanced laryngeal cancerFunctional consequence of the p53 codon 72 polymorphism in colorectal cancer.Single nucleotide polymorphisms and cancer susceptibility.
P2860
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P2860
Gain-of-function mutations in the tumor suppressor gene p53.
description
2000 nî lūn-bûn
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2000 թուականի Յունիսին հրատարակուած գիտական յօդուած
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2000 թվականի հունիսին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
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2000年論文
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2000年論文
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2000年論文
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2000年論文
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2000年论文
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name
Gain-of-function mutations in the tumor suppressor gene p53.
@ast
Gain-of-function mutations in the tumor suppressor gene p53.
@en
type
label
Gain-of-function mutations in the tumor suppressor gene p53.
@ast
Gain-of-function mutations in the tumor suppressor gene p53.
@en
prefLabel
Gain-of-function mutations in the tumor suppressor gene p53.
@ast
Gain-of-function mutations in the tumor suppressor gene p53.
@en
P1476
Gain-of-function mutations in the tumor suppressor gene p53
@en
P2093
Slootweg PJ
van Oijen MG
P304
P407
P577
2000-06-01T00:00:00Z