Closure of the Venus flytrap module of mGlu8 receptor and the activation process: Insights from mutations converting antagonists into agonists.
about
Evidence for a single heptahelical domain being turned on upon activation of a dimeric GPCRDifferent functional roles of T1R subunits in the heteromeric taste receptorsDistinct roles of metabotropic glutamate receptor dimerization in agonist activation and G-protein couplingOutside-in signaling--a brief review of GPCR signaling with a focus on the Drosophila GPCR familyBlocking metabotropic glutamate receptor subtype 7 (mGlu7) via the Venus flytrap domain (VFTD) inhibits amygdala plasticity, stress, and anxiety-related behaviorAllosteric modulation of metabotropic glutamate receptors.Metabotropic glutamate receptors: from the workbench to the bedside.High-potency olfactory receptor agonists discovered by virtual high-throughput screening: molecular probes for receptor structure and olfactory function.Structure and ligand recognition of class C GPCRsMutation-induced quisqualic acid and ibotenic acid affinity at the metabotropic glutamate receptor subtype 4: ligand selectivity results from a synergy of several amino acid residues.Gαo is required for L-canavanine detection in Drosophila.Interdomain movements in metabotropic glutamate receptor activation.Known regulators of nitric oxide synthase and arginase are agonists at the human G-protein-coupled receptor GPRC6A.Illuminating the activation mechanisms and allosteric properties of metabotropic glutamate receptorsEstimation of ligand efficacies of metabotropic glutamate receptors from conformational forces obtained from molecular dynamics simulations.How and why do GPCRs dimerize?Molecular basis for amino acid sensing by family C G-protein-coupled receptors.G-protein-coupled receptor oligomers: two or more for what? Lessons from mGlu and GABAB receptors.Metabotropic glutamate receptors: physiology, pharmacology, and disease.Dimers of G-protein coupled receptors as versatile storage and response unitsAllosteric modulation of metabotropic glutamate receptors: structural insights and therapeutic potential.Human biology of taste.Sequential inter- and intrasubunit rearrangements during activation of dimeric metabotropic glutamate receptor 1.Organization and functions of mGlu and GABAB receptor complexes.A missense mutation in the seven-transmembrane domain of the human Ca2+ receptor converts a negative allosteric modulator into a positive allosteric modulator.Asymmetric functioning of dimeric metabotropic glutamate receptors disclosed by positive allosteric modulators.Molecular determinants involved in the allosteric control of agonist affinity in the GABAB receptor by the GABAB2 subunit.Divergent evolution in metabotropic glutamate receptors. A new receptor activated by an endogenous ligand different from glutamate in insects.Molecular similarities in the ligand binding pockets of an odorant receptor and the metabotropic glutamate receptors.Delineating a Ca2+ binding pocket within the venus flytrap module of the human calcium-sensing receptor.
P2860
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P2860
Closure of the Venus flytrap module of mGlu8 receptor and the activation process: Insights from mutations converting antagonists into agonists.
description
2002 nî lūn-bûn
@nan
2002 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Closure of the Venus flytrap m ...... ing antagonists into agonists.
@ast
Closure of the Venus flytrap m ...... ing antagonists into agonists.
@en
Closure of the Venus flytrap m ...... ing antagonists into agonists.
@nl
type
label
Closure of the Venus flytrap m ...... ing antagonists into agonists.
@ast
Closure of the Venus flytrap m ...... ing antagonists into agonists.
@en
Closure of the Venus flytrap m ...... ing antagonists into agonists.
@nl
prefLabel
Closure of the Venus flytrap m ...... ing antagonists into agonists.
@ast
Closure of the Venus flytrap m ...... ing antagonists into agonists.
@en
Closure of the Venus flytrap m ...... ing antagonists into agonists.
@nl
P2093
P2860
P356
P1476
Closure of the Venus flytrap m ...... ing antagonists into agonists.
@en
P2093
Anne-Sophie Bessis
Florence Gaven
Francine Acher
Isabelle Brabet
Jean-Philippe Pin
Laurent Prezeau
Nicolas Triballeau
Philippe Rondard
P2860
P304
11097-11102
P356
10.1073/PNAS.162138699
P407
P577
2002-07-31T00:00:00Z