Nucleosome-binding activities within JARID2 and EZH1 regulate the function of PRC2 on chromatin.
about
Post-transcriptional gene silencing, transcriptional gene silencing and human immunodeficiency virusNormal formation of a vertebrate body plan and loss of tissue maintenance in the absence of ezh2.Combined Overexpression of JARID2, PRDM14, ESRRB, and SALL4A Dramatically Improves Efficiency and Kinetics of Reprogramming to Induced Pluripotent Stem Cells.A dimeric state for PRC2Interactions between JARID2 and noncoding RNAs regulate PRC2 recruitment to chromatin.Jarid2 is essential for the maintenance of tumor initiating cells in bladder cancer.Regulatory interactions between RNA and polycomb repressive complex 2.Jarid2 Methylation via the PRC2 Complex Regulates H3K27me3 Deposition during Cell Differentiation.Nascent RNA interaction keeps PRC2 activity poised and in check.Chromatin association of XRCC5/6 in the absence of DNA damage depends on the XPE gene product DDB2.Developmental control of polycomb subunit composition by GATA factors mediates a switch to non-canonical functions.From discovery to function: the expanding roles of long noncoding RNAs in physiology and disease.Jarid2 is induced by TCR signalling and controls iNKT cell maturation.Influence of ND10 components on epigenetic determinants of early KSHV latency establishment.Different nucleosomal architectures at early and late replicating origins in Saccharomyces cerevisiae.Jarid2 regulates hematopoietic stem cell function by acting with polycomb repressive complex 2.Dynamic interplay and function of multiple noncoding genes governing X chromosome inactivation.Transition of differential histone H3 methylation in photoreceptors and other retinal cells during retinal differentiation.Jarid2 binds mono-ubiquitylated H2A lysine 119 to mediate crosstalk between Polycomb complexes PRC1 and PRC2.Deciphering the epigenetic code of T lymphocytes.Role of PRC2-associated factors in stem cells and disease.The roles and regulation of Polycomb complexes in neural development.Regulation of gene transcription by Polycomb proteins.Mutations and deletions of PRC2 in prostate cancer.Epigenetic balance of gene expression by Polycomb and COMPASS families.Structure of the PRC2 complex and application to drug discovery.Epigenetic Heterogeneity of B-Cell Lymphoma: Chromatin Modifiers.Jarid2 Coordinates Nanog Expression and PCP/Wnt Signaling Required for Efficient ESC Differentiation and Early Embryo Development.Structure-Activity Relationship Studies for Enhancer of Zeste Homologue 2 (EZH2) and Enhancer of Zeste Homologue 1 (EZH1) Inhibitors.Single-molecule kinetic analysis of HP1-chromatin binding reveals a dynamic network of histone modification and DNA interactions.Function of JARID2 in bovines during early embryonic development.Polycomb Repressive Complex 2 Methylates Elongin A to Regulate Transcription.Molecular analysis of PRC2 recruitment to DNA in chromatin and its inhibition by RNA.Cryo-EM structures of PRC2 simultaneously engaged with two functionally distinct nucleosomes.EZH2 Regulates the Developmental Timing of Effectors of the Pre-Antigen Receptor Checkpoints.Structures of human PRC2 with its cofactors AEBP2 and JARID2.A cytosolic Ezh1 isoform modulates a PRC2-Ezh1 epigenetic adaptive response in postmitotic cells.Allosteric Activation Dictates PRC2 Activity Independent of Its Recruitment to Chromatin.Distinct Stimulatory Mechanisms Regulate the Catalytic Activity of Polycomb Repressive Complex 2.Unique Structural Platforms of Suz12 Dictate Distinct Classes of PRC2 for Chromatin Binding.
P2860
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P2860
Nucleosome-binding activities within JARID2 and EZH1 regulate the function of PRC2 on chromatin.
description
2013 nî lūn-bûn
@nan
2013 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Nucleosome-binding activities ...... function of PRC2 on chromatin.
@ast
Nucleosome-binding activities ...... function of PRC2 on chromatin.
@en
Nucleosome-binding activities ...... function of PRC2 on chromatin.
@nl
type
label
Nucleosome-binding activities ...... function of PRC2 on chromatin.
@ast
Nucleosome-binding activities ...... function of PRC2 on chromatin.
@en
Nucleosome-binding activities ...... function of PRC2 on chromatin.
@nl
prefLabel
Nucleosome-binding activities ...... function of PRC2 on chromatin.
@ast
Nucleosome-binding activities ...... function of PRC2 on chromatin.
@en
Nucleosome-binding activities ...... function of PRC2 on chromatin.
@nl
P2860
P356
P1433
P1476
Nucleosome-binding activities ...... function of PRC2 on chromatin.
@en
P2093
Jinsook Son
Raphael Margueron
P2860
P304
P356
10.1101/GAD.225888.113
P577
2013-12-01T00:00:00Z