Perturbation of 60 S ribosomal biogenesis results in ribosomal protein L5- and L11-dependent p53 activation
about
Positive regulation of p53 stability and activity by the deubiquitinating enzyme Otubain 1An extensive network of information flow through the B1b/c intersubunit bridge of the yeast ribosomeThe 5S RNP couples p53 homeostasis to ribosome biogenesis and nucleolar stressNucleolar stress induces ubiquitination-independent proteasomal degradation of PICT1 proteinATM-dependent E2F1 accumulation in the nucleolus is an indicator of ribosomal stress in early response to DNA damage.The human nucleolar protein FTSJ3 associates with NIP7 and functions in pre-rRNA processingRibosomal proteins and human diseases: pathogenesis, molecular mechanisms, and therapeutic implicationsRibosomal proteins: functions beyond the ribosomeInvolvement of human ribosomal proteins in nucleolar structure and p53-dependent nucleolar stressA microarray-based gene expression analysis to identify diagnostic biomarkers for unknown primary cancerRibosomal proteins RPL37, RPS15 and RPS20 regulate the Mdm2-p53-MdmX networkInterplay between ribosomal protein S27a and MDM2 protein in p53 activation in response to ribosomal stress.Hydrophilic residues are crucial for ribosomal protein L11 (RPL11) interaction with zinc finger domain of MDM2 and p53 protein activationGrowth inhibitory effects of large subunit ribosomal proteins in melanoma.Importin 7 and exportin 1 link c-Myc and p53 to regulation of ribosomal biogenesisPhysical and functional interaction between ribosomal protein L11 and the tumor suppressor ARF.Mammalian HCA66 protein is required for both ribosome synthesis and centriole duplicationImportant genes in the pathogenesis of 5q- syndrome and their connection with ribosomal stress and the innate immune system pathway.Depletion of ribosomal protein L37 occurs in response to DNA damage and activates p53 through the L11/MDM2 pathway.Nerve growth factor receptor negates the tumor suppressor p53 as a feedback regulatorSirtuin 7 plays a role in ribosome biogenesis and protein synthesis.Scission of the p53-MDM2 Loop by Ribosomal Proteins.Targeting the ubiquitin-mediated proteasome degradation of p53 for cancer therapy.p53 -Dependent and -Independent Nucleolar Stress Responses.Ribosomal protein L11 recruits miR-24/miRISC to repress c-Myc expression in response to ribosomal stressThe NEDD8 inhibitor MLN4924 increases the size of the nucleolus and activates p53 through the ribosomal-Mdm2 pathway.MicroRNA-130a associates with ribosomal protein L11 to suppress c-Myc expression in response to UV irradiation.Probing the mechanisms underlying human diseases in making ribosomes.Down-regulation of ribosomal protein L22 in non-small cell lung cancer.Recruitment of RPL11 at promoter sites of p53-regulated genes upon nucleolar stress through NEDD8 and in an Mdm2-dependent manner.Ribosomal protein S14 unties the MDM2-p53 loop upon ribosomal stress.RP-MDM2-p53 Pathway: Linking Ribosomal Biogenesis and Tumor Surveillance.Inhibition of post-transcriptional steps in ribosome biogenesis confers cytoprotection against chemotherapeutic agents in a p53-dependent manner.Ribosomal protein L4 is a novel regulator of the MDM2-p53 loop.Balanced production of ribosome components is required for proper G1/S transition in Saccharomyces cerevisiae.The ribosomal protein S26 regulates p53 activity in response to DNA damage.Nol12 is a multifunctional RNA binding protein at the nexus of RNA and DNA metabolism.Cancer-mutated ribosome protein L22 (RPL22/eL22) suppresses cancer cell survival by blocking p53-MDM2 circuit.Two Nucleolar Proteins, GDP1 and OLI2, Function As Ribosome Biogenesis Factors and Are Preferentially Involved in Promotion of Leaf Cell Proliferation without Strongly Affecting Leaf Adaxial-Abaxial Patterning in Arabidopsis thaliana.
P2860
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P2860
Perturbation of 60 S ribosomal biogenesis results in ribosomal protein L5- and L11-dependent p53 activation
description
2010 nî lūn-bûn
@nan
2010 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Perturbation of 60 S ribosomal ...... d L11-dependent p53 activation
@ast
Perturbation of 60 S ribosomal ...... d L11-dependent p53 activation
@en
Perturbation of 60 S ribosomal ...... d L11-dependent p53 activation
@nl
type
label
Perturbation of 60 S ribosomal ...... d L11-dependent p53 activation
@ast
Perturbation of 60 S ribosomal ...... d L11-dependent p53 activation
@en
Perturbation of 60 S ribosomal ...... d L11-dependent p53 activation
@nl
prefLabel
Perturbation of 60 S ribosomal ...... d L11-dependent p53 activation
@ast
Perturbation of 60 S ribosomal ...... d L11-dependent p53 activation
@en
Perturbation of 60 S ribosomal ...... d L11-dependent p53 activation
@nl
P2093
P2860
P356
P1476
Perturbation of 60 S ribosomal ...... d L11-dependent p53 activation
@en
P2093
Dimitris P Xirodimas
Mu-Shui Dai
Xiao-Xin Sun
Yue-Gang Wang
P2860
P304
25812-25821
P356
10.1074/JBC.M109.098442
P407
P577
2010-06-16T00:00:00Z