γ-secretase-dependent cleavage initiates notch signaling from the plasma membrane
about
The adaptor-associated kinase 1, AAK1, is a positive regulator of the Notch pathwayThe resveratrol trimer miyabenol C inhibits β-secretase activity and β-amyloid generationΑvβ3-integrin-mediated adhesion is regulated through an AAK1L- and EHD3-dependent rapid-recycling pathwayNotch signalling in T-cell lymphoblastic leukaemia/lymphoma and other haematological malignancies.The H(+) vacuolar ATPase maintains neural stem cells in the developing mouse cortex.Down-regulation of the ATP-binding cassette transporter 2 (Abca2) reduces amyloid-β production by altering Nicastrin maturation and intracellular localization.Function of Integrin-Linked Kinase in Modulating the Stemness of IL-6-Abundant Breast Cancer Cells by Regulating γ-Secretase-Mediated Notch1 Activation in Caveolae.Caenorhabditis elegans reveals a FxNPxY-independent low-density lipoprotein receptor internalization mechanism mediated by epsin1.Notch signaling from the endosome requires a conserved dileucine motif.Membrane tethered delta activates notch and reveals a role for spatio-mechanical regulation of the signaling pathway.The role and therapeutic targeting of α-, β- and γ-secretase in Alzheimer's diseaseInterferon regulatory factor 4 attenuates Notch signaling to suppress the development of chronic lymphocytic leukemia.The multiple facets of ubiquitination in the regulation of notch signaling pathway.Regulation of developmental intercellular signalling by intracellular trafficking.The role of endocytosis in activating and regulating signal transduction.The very many faces of presenilins and the γ-secretase complex.Therapeutic modulation of Notch signalling--are we there yet?PKCζ regulates Notch receptor routing and activity in a Notch signaling-dependent manner.Portrayal of the Notch system in embryonic stem cell-derived embryoid bodies.YAP/TAZ link cell mechanics to Notch signalling to control epidermal stem cell fateBioelectric state and cell cycle control of Mammalian neural stem cells.The type III TGF-β receptor betaglycan transmembrane-cytoplasmic domain fragment is stable after ectodomain cleavage and is a substrate of the intramembrane protease γ-secretase.Notch Signaling in Development, Tissue Homeostasis, and Disease.The curious case of vacuolar ATPase: regulation of signaling pathways.PI5P4Kγ functions in DTX1-mediated Notch signaling.Histone deacetylase 6 controls Notch3 trafficking and degradation in T-cell acute lymphoblastic leukemia cells.Glycogen synthase kinase 3β inhibition enhances Notch1 recycling.A Review of Notch Processing With New Insights Into Ligand-Independent Notch Signaling in T-Cells.
P2860
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P2860
γ-secretase-dependent cleavage initiates notch signaling from the plasma membrane
description
2010 nî lūn-bûn
@nan
2010 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年学术文章
@wuu
2010年学术文章
@zh-cn
2010年学术文章
@zh-hans
2010年学术文章
@zh-my
2010年学术文章
@zh-sg
2010年學術文章
@yue
name
γ-secretase-dependent cleavage initiates notch signaling from the plasma membrane
@ast
γ-secretase-dependent cleavage initiates notch signaling from the plasma membrane
@en
γ-secretase-dependent cleavage initiates notch signaling from the plasma membrane
@nl
type
label
γ-secretase-dependent cleavage initiates notch signaling from the plasma membrane
@ast
γ-secretase-dependent cleavage initiates notch signaling from the plasma membrane
@en
γ-secretase-dependent cleavage initiates notch signaling from the plasma membrane
@nl
prefLabel
γ-secretase-dependent cleavage initiates notch signaling from the plasma membrane
@ast
γ-secretase-dependent cleavage initiates notch signaling from the plasma membrane
@en
γ-secretase-dependent cleavage initiates notch signaling from the plasma membrane
@nl
P2860
P1433
P1476
γ-secretase-dependent cleavage initiates notch signaling from the plasma membrane
@en
P2093
Erika B Sorensen
Sean D Conner
P2860
P304
P356
10.1111/J.1600-0854.2010.01090.X
P577
2010-06-21T00:00:00Z