Different biochemical properties explain why two equivalent Gα subunit mutants cause unrelated diseases - sprookjes - yvandenbroek - TriplyDB

Different biochemical properties explain why two equivalent Gα subunit mutants cause unrelated diseases

Different biochemical properties explain why two equivalent Gα subunit mutants cause unrelated diseases

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Registered report: Diverse somatic mutation patterns and pathway alterations in human cancers Evolutionary Conservation of a GPCR-Independent Mechanism of Trimeric G Protein Activation Dominant-negative Gα subunits are a mechanism of dysregulated heterotrimeric G protein signaling in human disease.GIV/Girdin activates Gαi and inhibits Gαs via the same motif Integration of Fourier Transform Infrared Spectroscopy, Fluorescence Spectroscopy, Steady-state Kinetics and Molecular Dynamics Simulations of Gαi1 Distinguishes between the GTP Hydrolysis and GDP Release Mechanism.Dynamic regulation of GDP binding to G proteins revealed by magnetic field-dependent NMR relaxation analyses.Disease-Causing Mutations in the G Protein Gαs Subvert the Roles of GDP and GTP.

P2860

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P2860

Different biochemical properties explain why two equivalent Gα subunit mutants cause unrelated diseases

http://www.wikidata.org/entity/Q34070311

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2014 թուականի Յունիսին հրատարակուած գիտական յօդուած

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2014 թվականի հունիսին հրատարակված գիտական հոդված

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2014年の論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年论文

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Different biochemical properti ...... tants cause unrelated diseases

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Different biochemical properti ...... tants cause unrelated diseases

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Different biochemical properti ...... tants cause unrelated diseases

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label

Different biochemical properti ...... tants cause unrelated diseases

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Different biochemical properti ...... tants cause unrelated diseases

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Different biochemical properti ...... tants cause unrelated diseases

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prefLabel

Different biochemical properti ...... tants cause unrelated diseases

@ast

Different biochemical properti ...... tants cause unrelated diseases

@en

Different biochemical properti ...... tants cause unrelated diseases

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JBC.M114.549790

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Journal of Biological Chemistry

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Different biochemical properti ...... tants cause unrelated diseases

@en

P2093

Anthony Leyme

http://www.w3.org/2001/XMLSchema#string

Arthur Marivin

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Jason Casler

http://www.w3.org/2001/XMLSchema#string

Lien T Nguyen

http://www.w3.org/2001/XMLSchema#string

Mikel Garcia-Marcos

http://www.w3.org/2001/XMLSchema#string

P2860

A novel mutation in the switch 3 region of Gsalpha in a patient with Albright hereditary osteodystrophy impairs GDP binding and receptor activation

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Molecular architecture of G o and the structural basis for RGS16-mediated deactivation

Structures of active conformations of Gi alpha 1 and the mechanism of GTP hydrolysis

Crystal structure of the adenylyl cyclase activator Gsalpha

The A326S mutant of Gialpha1 as an approximation of the receptor-bound state

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21818-21827

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scholarly article

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10.1074/JBC.M114.549790

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32

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289

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2014-06-30T00:00:00Z

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4139202

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