Signal transduction mediated by the T cell antigen receptor: the role of adapter proteins.
about
Releasing the brake: targeting Cbl-b to enhance lymphocyte effector functionsEfficient T-cell receptor signaling requires a high-affinity interaction between the Gads C-SH3 domain and the SLP-76 RxxK motifAbl-SH3 binding protein 2, 3BP2, interacts with CIN85 and HIP-55Synergistic assembly of linker for activation of T cells signaling protein complexes in T cell plasma membrane domainsOligomerization of signaling complexes by the multipoint binding of GRB2 to both LAT and SOS1Identification of substrates of human protein-tyrosine phosphatase PTPN22Regulation and function of SKAP-55 non-canonical motif binding to the SH3c domain of adhesion and degranulation-promoting adaptor proteinRecruitment and activation of PLCgamma1 in T cells: a new insight into old domainsThe importance of three membrane-distal tyrosines in the adaptor protein NTAL/LABExpression, refolding and crystallizations of the Grb2-like (GADS) C-terminal SH3 domain complexed with a SLP-76 motif peptideHIP-55 is important for T-cell proliferation, cytokine production, and immune responsesUltrasensitivity in multisite phosphorylation of membrane-anchored proteinsOsteoimmunology: interactions of the bone and immune systemLIME: a new membrane Raft-associated adaptor protein involved in CD4 and CD8 coreceptor signalingAn essential role for RasGRP1 in mast cell function and IgE-mediated allergic responseModeling T cell antigen discrimination based on feedback control of digital ERK responsesRegulation of the human LAT gene by the Elf-1 transcription factorSignaling in T cells - is anything the m(a)TOR with the picture(s)?Disturbed T Cell Signaling and Altered Th17 and Regulatory T Cell Subsets in the Pathogenesis of Systemic Lupus ErythematosusSuper-resolution characterization of TCR-dependent signaling clustersStructural Insights into the Assembly of CARMA1 and BCL10Rap1-mediated lymphocyte function-associated antigen-1 activation by the T cell antigen receptor is dependent on phospholipase C-gamma1Recruitment of the actin-binding protein HIP-55 to the immunological synapse regulates T cell receptor signaling and endocytosisCD28 and CTLA-4 coreceptor expression and signal transductionSLP76 and SLP65: complex regulation of signalling in lymphocytes and beyondA leucine zipper in the N terminus confers membrane association to SLP-65Comparison of T cell receptor-induced proximal signaling and downstream functions in immortalized and primary T cellsIdentification of a new transmembrane adaptor protein that constitutively binds Grb2 in B cellsThe protein tyrosine phosphatase PTPN4/PTP-MEG1, an enzyme capable of dephosphorylating the TCR ITAMs and regulating NF-kappaB, is dispensable for T cell development and/or T cell effector functionsInositol (1,4,5) trisphosphate 3 kinase B controls positive selection of T cells and modulates Erk activityEphB6-null mutation results in compromised T cell functionImpaired immune responses and prolonged allograft survival in Sly1 mutant micePhosphorylation-dependent regulation of T-cell activation by PAG/Cbp, a lipid raft-associated transmembrane adaptorGRB2 Nucleates T Cell Receptor-Mediated LAT Clusters That Control PLC-γ1 Activation and Cytokine Production.Allostery mediates ligand binding to Grb2 adaptor in a mutually exclusive manner.Competition between SLP76 and LAT for PLCγ1 binding in resting T cells.3BP2 adapter protein is required for receptor activator of NFκB ligand (RANKL)-induced osteoclast differentiation of RAW264.7 cells.Crystallization and initial crystal characterization of the C-terminal phosphoglycerate mutase homology domain of Sts-1.Structural basis for recognition of the T cell adaptor protein SLP-76 by the SH3 domain of phospholipase Cgamma1SHIP family inositol phosphatases interact with and negatively regulate the Tec tyrosine kinase.
P2860
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P2860
Signal transduction mediated by the T cell antigen receptor: the role of adapter proteins.
description
2001 nî lūn-bûn
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2001 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2001年の論文
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2001年学术文章
@wuu
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
name
Signal transduction mediated b ...... the role of adapter proteins.
@ast
Signal transduction mediated b ...... the role of adapter proteins.
@en
Signal transduction mediated b ...... the role of adapter proteins.
@nl
type
label
Signal transduction mediated b ...... the role of adapter proteins.
@ast
Signal transduction mediated b ...... the role of adapter proteins.
@en
Signal transduction mediated b ...... the role of adapter proteins.
@nl
prefLabel
Signal transduction mediated b ...... the role of adapter proteins.
@ast
Signal transduction mediated b ...... the role of adapter proteins.
@en
Signal transduction mediated b ...... the role of adapter proteins.
@nl
P1476
Signal transduction mediated b ...... the role of adapter proteins.
@en
P2093
Lawrence E Samelson
P304
P356
10.1146/ANNUREV.IMMUNOL.20.092601.111357
P577
2001-10-04T00:00:00Z