Small molecule kinase inhibitors in glioblastoma: a systematic review of clinical studies.
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Identifying new small molecule anti-invasive compounds for glioma treatmentProcarbazine, carmustine, and vincristine (PBV) for chemotherapy pre-treated patients with recurrent glioblastoma: a single-institution analysis.Genome-wide shRNA screen revealed integrated mitogenic signaling between dopamine receptor D2 (DRD2) and epidermal growth factor receptor (EGFR) in glioblastomaMultivariate signaling regulation by SHP2 differentially controls proliferation and therapeutic response in glioma cellsBetter prognosis of patients with glioma expressing FGF2-dependent PDGFRA irrespective of morphological diagnosis.Glial progenitors as targets for transformation in glioma.EGFR expression stratifies oligodendroglioma behavior.Overcoming the challenges in the effective delivery of chemotherapies to CNS solid tumors.Targeting PBK/TOPK decreases growth and survival of glioma initiating cells in vitro and attenuates tumor growth in vivoIntratumoral heterogeneity of receptor tyrosine kinases EGFR and PDGFRA amplification in glioblastoma defines subpopulations with distinct growth factor responseCurrent trends in targeted therapies for glioblastoma multiformeEmerging insights into the molecular and cellular basis of glioblastoma.Small-molecule inhibition of PTPRZ reduces tumor growth in a rat model of glioblastoma.Studying a complex tumor: potential and pitfalls.Dose-dense temozolomide: is it still promising?Single-cell sequencing maps gene expression to mutational phylogenies in PDGF- and EGF-driven gliomasActive efflux of Dasatinib from the brain limits efficacy against murine glioblastoma: broad implications for the clinical use of molecularly targeted agents.Sprouty2 Drives Drug Resistance and Proliferation in Glioblastoma.Platelet-derived growth factor receptor alpha in glioma: a bad seedType-3 metabotropic glutamate receptors regulate chemoresistance in glioma stem cells, and their levels are inversely related to survival in patients with malignant gliomas.Assessing current therapeutic approaches to decode potential resistance mechanisms in glioblastomas.In Vitro and In Vivo Analysis of RTK Inhibitor Efficacy and Identification of Its Novel Targets in Glioblastomas.A bivalent recombinant immunotoxin with high potency against tumors with EGFR and EGFRvIII expression.Treating brain tumor-initiating cells using a combination of myxoma virus and rapamycinImatinib and Nilotinib increase glioblastoma cell invasion via Abl-independent stimulation of p130Cas and FAK signalling.The soluble form of the tumor suppressor Lrig1 potently inhibits in vivo glioma growth irrespective of EGF receptor status.Co-expression modules of NF1, PTEN and sprouty enable distinction of adult diffuse gliomas according to pathway activities of receptor tyrosine kinasesDisabled cell density sensing leads to dysregulated cholesterol synthesis in glioblastoma.Malignant gliomas: new translational therapies.Signal transduction inhibitors and antiangiogenic therapies for malignant glioma.Molecular subclassification of diffuse gliomas: seeing order in the chaos.The molecular basis for novel therapies.Paediatric and adult malignant glioma: close relatives or distant cousins?Pediatric neuro-oncology: current status and future directions.Mechanism of chemoresistance against tyrosine kinase inhibitors in malignant glioma.Expression Profiling of the MAP Kinase Phosphatase Family Reveals a Role for DUSP1 in the Glioblastoma Stem Cell Niche.Genetic biomarkers of drug response for small-molecule therapeutics targeting the RTK/Ras/PI3K, p53 or Rb pathway in glioblastoma.HDAC7 inhibition resets STAT3 tumorigenic activity in human glioblastoma independently of EGFR and PTEN: new opportunities for selected targeted therapies.Investigational new drugs for brain cancer.Modulatory Effects of Curcumin and Tyrphostins (AG494 and AG1478) on Growth Regulation and Viability of LN229 Human Brain Cancer Cells.
P2860
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P2860
Small molecule kinase inhibitors in glioblastoma: a systematic review of clinical studies.
description
2010 nî lūn-bûn
@nan
2010 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Small molecule kinase inhibito ...... ic review of clinical studies.
@ast
Small molecule kinase inhibito ...... ic review of clinical studies.
@en
Small molecule kinase inhibito ...... ic review of clinical studies.
@nl
type
label
Small molecule kinase inhibito ...... ic review of clinical studies.
@ast
Small molecule kinase inhibito ...... ic review of clinical studies.
@en
Small molecule kinase inhibito ...... ic review of clinical studies.
@nl
prefLabel
Small molecule kinase inhibito ...... ic review of clinical studies.
@ast
Small molecule kinase inhibito ...... ic review of clinical studies.
@en
Small molecule kinase inhibito ...... ic review of clinical studies.
@nl
P2860
P356
P1433
P1476
Small molecule kinase inhibito ...... ic review of clinical studies.
@en
P2860
P304
P356
10.1093/NEUONC/NOP068
P577
2010-02-09T00:00:00Z