Accommodation of physostigmine and its analogues by acetylcholinesterase is dominated by hydrophobic interactions. - sprookjes - yvandenbroek - TriplyDB

Accommodation of physostigmine and its analogues by acetylcholinesterase is dominated by hydrophobic interactions.

Accommodation of physostigmine and its analogues by acetylcholinesterase is dominated by hydrophobic interactions.

http://www.wikidata.org/entity/Q34171486

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Kinetics of Torpedo californica acetylcholinesterase inhibition by bisnorcymserine and crystal structure of the complex with its leaving group Chiral toxicology: it's the same thing...only different.Nature as a source of metabolites with cholinesterase-inhibitory activity: an approach to Alzheimer's disease treatment.How does curcumin work with poor bioavailability? Clues from experimental and theoretical studies.In vitro inhibitory profile of NDGA against AChE and its in silico structural modifications based on ADME profile.Pharmacophore-based design and discovery of (-)-meptazinol carbamates as dual modulators of cholinesterase and amyloidogenesis.Interaction of metal chelators with different molecular forms of acetylcholinesterase and its significance in Alzheimer's disease treatment.

P2860

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P2860

Accommodation of physostigmine and its analogues by acetylcholinesterase is dominated by hydrophobic interactions.

http://www.wikidata.org/entity/Q34171486

description

2009 nî lūn-bûn

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2009 թուականի Յունուարին հրատարակուած գիտական յօդուած

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2009 թվականի հունվարին հրատարակված գիտական հոդված

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2009年の論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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Accommodation of physostigmine ...... d by hydrophobic interactions.

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Accommodation of physostigmine ...... d by hydrophobic interactions.

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Accommodation of physostigmine ...... d by hydrophobic interactions.

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Accommodation of physostigmine ...... d by hydrophobic interactions.

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Accommodation of physostigmine ...... d by hydrophobic interactions.

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Accommodation of physostigmine ...... d by hydrophobic interactions.

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Accommodation of physostigmine ...... d by hydrophobic interactions.

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Accommodation of physostigmine ...... d by hydrophobic interactions.

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Accommodation of physostigmine ...... d by hydrophobic interactions.

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Accommodation of physostigmine ...... d by hydrophobic interactions.

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Arie Ordentlich

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Avigdor Shafferman

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Dana Stein

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Dov Barak

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Nigel H Greig

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Qian-Sheng Yu

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P2860

Dissection of the human acetylcholinesterase active center determinants of substrate specificity. Identification of residues constituting the anionic site, the hydrophobic site, and the acyl pocket

The 'aromatic patch' of three proximal residues in the human acetylcholinesterase active centre allows for versatile interaction modes with inhibitors

Quaternary ligand binding to aromatic residues in the active-site gorge of acetylcholinesterase

A new and rapid colorimetric determination of acetylcholinesterase activity

Structure of acetylcholinesterase complexed with E2020 (Aricept): implications for the design of new anti-Alzheimer drugs

Structures of recombinant native and E202Q mutant human acetylcholinesterase complexed with the snake-venom toxin fasciculin-II

Kinetic and structural studies on the interaction of cholinesterases with the anti-Alzheimer drug rivastigmine

The cholinesterases: from genes to proteins

Atomic structure of acetylcholinesterase from Torpedo californica: a prototypic acetylcholine-binding protein

Contribution of aromatic moieties of tyrosine 133 and of the anionic subsite tryptophan 86 to catalytic efficiency and allosteric modulation of acetylcholinesterase

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213-222

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10.1042/BJ20081276

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1

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