Direct regulation of GAS6/AXL signaling by HIF promotes renal metastasis through SRC and MET.
about
Cabozantinib in the treatment of advanced renal cell carcinoma: design, development, and potential place in the therapyHypoxic control of metastasisTargeting hypoxic response for cancer therapyProgress toward overcoming hypoxia-induced resistance to solid tumor therapyThe Receptor Tyrosine Kinase AXL in Cancer ProgressionCabozantinib in the treatment of advanced renal cell carcinoma: clinical trial evidence and experienceLigand Activation of TAM Family Receptors-Implications for Tumor Biology and Therapeutic ResponseImplications of Hypoxia in Breast Cancer Metastasis to BoneFor robust big data analyses: a collection of 150 important pro-metastatic genesKDM4B/JMJD2B is a p53 target gene that modulates the amplitude of p53 response after DNA damage.Cabozantinib versus Everolimus in Advanced Renal-Cell CarcinomaAXL is a potential therapeutic target in dedifferentiated and pleomorphic liposarcomas.Anti-Tumor Effects of Second Generation β-Hydroxylase Inhibitors on Cholangiocarcinoma Development and Progression.Cabozantinib Versus Sunitinib As Initial Targeted Therapy for Patients With Metastatic Renal Cell Carcinoma of Poor or Intermediate Risk: The Alliance A031203 CABOSUN Trial.Novel Axl-driven signaling pathway and molecular signature characterize high-grade ovarian cancer patients with poor clinical outcome.Repurposing the anti-malarial drug artesunate as a novel therapeutic agent for metastatic renal cell carcinoma due to its attenuation of tumor growth, metastasis, and angiogenesis.Global phosphotyrosine survey in triple-negative breast cancer reveals activation of multiple tyrosine kinase signaling pathways.Normalization of TAM post-receptor signaling reveals a cell invasive signature for Axl tyrosine kinase.Hypoxia, Hypoxia-inducible Transcription Factors, and Renal Cancer.Reprogramming the immunological microenvironment through radiation and targeting Axl.Inhibition of the GAS6/AXL pathway augments the efficacy of chemotherapies.New treatment options for metastatic renal cell carcinoma with prior anti-angiogenesis therapyCabozantinib: an Active Novel Multikinase Inhibitor in Renal Cell Carcinoma.AXL modulates extracellular matrix protein expression and is essential for invasion and metastasis in endometrial cancer.Sunitinib activates Axl signaling in renal cell cancer.Gene of the month: Axl.Giving AXL the axe: targeting AXL in human malignancy.Targeting MET and AXL overcomes resistance to sunitinib therapy in renal cell carcinoma.Novel therapeutic options for second-line therapy in metastatic renal cell carcinoma.Axl and Mer Receptor Tyrosine Kinases: Distinct and Nonoverlapping Roles in Inflammation and Cancer?The Wide Experience of the Sequential Therapy for Patients with Metastatic Renal Cell Carcinoma.Cabozantinib for the treatment of renal cell carcinoma.AXL receptor tyrosine kinase as a therapeutic target in NSCLC.Key Roles of AXL and MER Receptor Tyrosine Kinases in Resistance to Multiple Anticancer Therapies.Renal cell carcinoma: molecular characterization and evolving treatment paradigms.LncRNA HOTAIR regulates HIF-1α/AXL signaling through inhibition of miR-217 in renal cell carcinomaMolecular analysis of alternative transcripts of equine AXL receptor tyrosine kinase geneA comprehensive analysis of cancer-driving mutations and genes in kidney cancer.Protein S drives oral squamous cell carcinoma tumorigenicity through regulation of AXL.Small molecule inhibitors block Gas6-inducible TAM activation and tumorigenicity
P2860
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P2860
Direct regulation of GAS6/AXL signaling by HIF promotes renal metastasis through SRC and MET.
description
2014 nî lūn-bûn
@nan
2014 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Direct regulation of GAS6/AXL ...... etastasis through SRC and MET.
@ast
Direct regulation of GAS6/AXL ...... etastasis through SRC and MET.
@en
Direct regulation of GAS6/AXL ...... etastasis through SRC and MET.
@nl
type
label
Direct regulation of GAS6/AXL ...... etastasis through SRC and MET.
@ast
Direct regulation of GAS6/AXL ...... etastasis through SRC and MET.
@en
Direct regulation of GAS6/AXL ...... etastasis through SRC and MET.
@nl
prefLabel
Direct regulation of GAS6/AXL ...... etastasis through SRC and MET.
@ast
Direct regulation of GAS6/AXL ...... etastasis through SRC and MET.
@en
Direct regulation of GAS6/AXL ...... etastasis through SRC and MET.
@nl
P2093
P2860
P50
P356
P1476
Direct regulation of GAS6/AXL ...... metastasis through SRC and MET
@en
P2093
Amato J Giaccia
Anh N Diep
David Lindgren
Edward L LaGory
Elizabeth C Finger
Håkan Axelson
Kartik Viswanathan
Laura Castellini
Mihalis S Kariolis
P2860
P304
13373-13378
P356
10.1073/PNAS.1404848111
P407
P577
2014-09-03T00:00:00Z