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Epigenetic Therapy for Solid Tumors: Highlighting the Impact of Tumor HypoxiaHIF-KDM3A-MMP12 regulatory circuit ensures trophoblast plasticity and placental adaptations to hypoxia.Regulation of the histone demethylase JMJD1A by hypoxia-inducible factor 1 alpha enhances hypoxic gene expression and tumor growth.KDM4B/JMJD2B is a p53 target gene that modulates the amplitude of p53 response after DNA damage.The histone demethylase KDM4B regulates peritoneal seeding of ovarian cancer.Cross-talk between hypoxia and insulin signaling through Phd3 regulates hepatic glucose and lipid metabolism and ameliorates diabetesDirect regulation of GAS6/AXL signaling by HIF promotes renal metastasis through SRC and MET.VHL loss in renal cell carcinoma leads to up-regulation of CUB domain-containing protein 1 to stimulate PKC{delta}-driven migrationHypoxic induction of AKAP12 variant 2 shifts PKA-mediated protein phosphorylation to enhance migration and metastasis of melanoma cells.AXL is an essential factor and therapeutic target for metastatic ovarian cancerGenome-independent hypoxic repression of estrogen receptor alpha in breast cancer cells.Targeting the loss of the von Hippel-Lindau tumor suppressor gene in renal cell carcinoma cells.KDM4A regulates HIF-1 levels through H3K9me3.Genome-wide analysis of p53 under hypoxic conditions.Interactions of high mobility group box proteins with DNA and chromatin.KDM4B: A Nail for Every Hammer?Licofelone Enhances the Efficacy of Paclitaxel in Ovarian Cancer by Reversing Drug Resistance and Tumor Stem-like PropertiesCollagen Remodeling in the Hypoxic Tumor-Mesothelial Niche Promotes Ovarian Cancer Metastasis
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description
hulumtues
@sq
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Adam J. Krieg
@ast
Adam J. Krieg
@en
Adam J. Krieg
@es
Adam J. Krieg
@nl
type
label
Adam J. Krieg
@ast
Adam J. Krieg
@en
Adam J. Krieg
@es
Adam J. Krieg
@nl
prefLabel
Adam J. Krieg
@ast
Adam J. Krieg
@en
Adam J. Krieg
@es
Adam J. Krieg
@nl
P106
P1153
36919926500
P21
P31
P496
0000-0002-3069-0378