Molecular properties and involvement of heparanase in cancer metastasis and angiogenesis. - sprookjes - yvandenbroek - TriplyDB

Molecular properties and involvement of heparanase in cancer metastasis and angiogenesis.

Molecular properties and involvement of heparanase in cancer metastasis and angiogenesis.

http://www.wikidata.org/entity/Q34328744

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Heparanase enhances the generation of activated factor X in the presence of tissue factor and activated factor VII HSulf-2, an extracellular endoglucosamine-6-sulfatase, selectively mobilizes heparin-bound growth factors and chemokines: effects on VEGF, FGF-1, and SDF-1.Heparin: Past, Present, and Future Glycoconjugates and related molecules in human vascular endothelial cells Involvement of heparanase in atherosclerosis and other vessel wall pathologies Newly generated heparanase knock-out mice unravel co-regulation of heparanase and matrix metalloproteinases Heparanase induces Akt phosphorylation via a lipid raft receptor IL-1 is required for tumor invasiveness and angiogenesis Heparan sulfate signaling in cancer Positive association of heparanase expression with tumor invasion and lymphatic metastasis in gastric carcinoma.Viral Activation of Heparanase Drives Pathogenesis of Herpes Simplex Virus-1.Development and NMR validation of minimal pharmacophore hypotheses for the generation of fragment libraries enriched in heparanase inhibitors.Small RNA interference-mediated gene silencing of heparanase abolishes the invasion, metastasis and angiogenesis of gastric cancer cells Heparanase promotes engraftment and prevents graft versus host disease in stem cell transplantation Heparanase and hepatocellular carcinoma: promoter or inhibitor?Expression of heparanase in soft tissue sarcomas of adults.Regulation of intracellular signaling by extracellular glycan remodeling.Modification of heparanase gene expression in response to conditioning and LPS treatment: strong correlation to rs4693608 SNP.Genetic variations in the heparanase gene (HPSE) associate with increased risk of GVHD following allogeneic stem cell transplantation: effect of discrepancy between recipients and donors A novel human heparanase splice variant, T5, endowed with protumorigenic characteristics.In vivo fragmentation of heparan sulfate by heparanase overexpression renders mice resistant to amyloid protein A amyloidosis Unraveling the specificity of heparanase utilizing synthetic substrates.Six blind men and the elephant--the many faces of heparan sulfate.Heparanase promotes neuroinflammatory response during subarachnoid hemorrhage in rats.The Quantification of Glycosaminoglycans: A Comparison of HPLC, Carbazole, and Alcian Blue Methods.CXCL7-Mediated Stimulation of Lymphangiogenic Factors VEGF-C, VEGF-D in Human Breast Cancer Cells Glycosaminoglycans in Human and Bovine Serum: Detection of Twenty-Four Heparan Sulfate and Chondroitin Sulfate Motifs Including a Novel Sialic Acid-modified Chondroitin Sulfate Linkage Hexasaccharide Heparanase cooperates with Ras to drive breast and skin tumorigenesis Adaptive evolution of heparanase in hypoxia-tolerant Spalax: gene cloning and identification of a unique splice variant.Cell surface expression and secretion of heparanase markedly promote tumor angiogenesis and metastasis Small RNAs targeting transcription start site induce heparanase silencing through interference with transcription initiation in human cancer cells Heparin and liver heparan sulfate can rescue hepatoma cells from topotecan action.Dissociation between mature phenotype and impaired transmigration in dendritic cells from heparanase-deficient mice.Heparanase promotes human gastric cancer cells migration and invasion by increasing Src and p38 phosphorylation expression.Processing of heparanase is mediated by syndecan-1 cytoplasmic domain and involves syntenin and α-actinin.The many faces of metalloproteases: cell growth, invasion, angiogenesis and metastasis.Prognostic value of heparanase expression and cellular localization in oral cancer.Heparanase and coagulation-new insights.Heparanase is a host enzyme required for herpes simplex virus-1 release from cells.Clinical significance of heparanase splice variant (t5) in renal cell carcinoma: evaluation by a novel t5-specific monoclonal antibody

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P2860

Molecular properties and involvement of heparanase in cancer metastasis and angiogenesis.

http://www.wikidata.org/entity/Q34328744

description

2001 nî lūn-bûn

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2001 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

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2001 թվականի օգոստոսին հրատարակված գիտական հոդված

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2001年の論文

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2001年論文

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2001年論文

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2001年論文

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2001年論文

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2001年論文

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2001年论文

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name

Molecular properties and involvement of heparanase in cancer metastasis and angiogenesis.

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Molecular properties and involvement of heparanase in cancer metastasis and angiogenesis.

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Molecular properties and involvement of heparanase in cancer metastasis and angiogenesis.

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type

label

Molecular properties and involvement of heparanase in cancer metastasis and angiogenesis.

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Molecular properties and involvement of heparanase in cancer metastasis and angiogenesis.

@en

Molecular properties and involvement of heparanase in cancer metastasis and angiogenesis.

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prefLabel

Molecular properties and involvement of heparanase in cancer metastasis and angiogenesis.

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Molecular properties and involvement of heparanase in cancer metastasis and angiogenesis.

@en

Molecular properties and involvement of heparanase in cancer metastasis and angiogenesis.

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Journal of Clinical Investigation

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Molecular properties and involvement of heparanase in cancer metastasis and angiogenesis.

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I Vlodavsky

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Y Friedmann

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P2860

Human heparanase. Purification, characterization, cloning, and expression

Mammalian heparanase: gene cloning, expression and function in tumor progression and metastasis

Cloning and expression profiling of Hpa2, a novel mammalian heparanase family member

Heparin and cancer revisited: mechanistic connections involving platelets, P-selectin, carcinoma mucins, and tumor metastasis

Cloning of mammalian heparanase, an important enzyme in tumor invasion and metastasis

Cloning and functional expression of a human heparanase gene

Identification of active-site residues of the pro-metastatic endoglycosidase heparanase

Matrix metalloproteinase-9 triggers the angiogenic switch during carcinogenesis

Genomic organization and chromosome localization of the newly identified human heparanase gene

Heparanase expression in primary and metastatic pancreatic cancer

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