Activation of transforming potential of the human insulin receptor gene - sprookjes - yvandenbroek - TriplyDB

Activation of transforming potential of the human insulin receptor gene

Activation of transforming potential of the human insulin receptor gene

http://www.wikidata.org/entity/Q34338615

about

Distinctive effects of the carboxyl-terminal sequence of the insulin-like growth factor I receptor on its signaling functions A subdomain in the transmembrane domain is necessary for p185neu* activation.RETRACTED: Soluble Axl is generated by ADAM10-dependent cleavage and associates with Gas6 in mouse serum Ala-->Gly mutation in the putative catalytic loop confers temperature sensitivity on Ros, insulin receptor, and insulin-like growth factor I receptor protein-tyrosine kinases.Transforming activity of retroviral genomes encoding Gag-Axl fusion proteins.Constitutive proteolysis of the ErbB-4 receptor tyrosine kinase by a unique, sequential mechanism.Enhancement of transforming potential of human insulinlike growth factor 1 receptor by N-terminal truncation and fusion to avian sarcoma virus UR2 gag sequence.Overexpression of the human insulinlike growth factor I receptor promotes ligand-dependent neoplastic transformation.Role of gag sequence in the biochemical properties and transforming activity of the avian sarcoma virus UR2-encoded gag-ros fusion protein Molecular basis of the activation of the tumorigenic potential of Gag-insulin receptor chimeras.Insulin--carcinogen or mitogen? Preclinical and clinical evidence from prostate, breast, pancreatic, and colorectal cancer research.Modulating effects of the extracellular sequence of the human insulinlike growth factor I receptor on its transforming and tumorigenic potential.Two point mutations in the transmembrane domain of P68gag-ros inactive its transforming activity and cause a delay in membrane association.Transforming properties and substrate specificities of the protein tyrosine kinase oncogenes ros and src and their recombinants.Differential requirements of the MAP kinase and PI3 kinase signaling pathways in Src- versus insulin and IGF-1 receptors-induced growth and transformation of rat intestinal epithelial cells.Proteolytic generation of constitutive tyrosine kinase activity of the human insulin receptor.Quantitation of IGF-I, IGF-II, and multiple insulin receptor family member messenger RNAs during embryonic development in rainbow trout.

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Activation of transforming potential of the human insulin receptor gene

http://www.wikidata.org/entity/Q34338615

description

1987 nî lūn-bûn

@nan

1987 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

1987 թվականի օգոստոսին հրատարակված գիտական հոդված

@hy

1987年の論文

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1987年論文

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1987年論文

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1987年論文

@zh-hk

1987年論文

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1987年論文

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1987年论文

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name

Activation of transforming potential of the human insulin receptor gene

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Activation of transforming potential of the human insulin receptor gene

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Activation of transforming potential of the human insulin receptor gene

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type

label

Activation of transforming potential of the human insulin receptor gene

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Activation of transforming potential of the human insulin receptor gene

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Activation of transforming potential of the human insulin receptor gene

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prefLabel

Activation of transforming potential of the human insulin receptor gene

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Activation of transforming potential of the human insulin receptor gene

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Activation of transforming potential of the human insulin receptor gene

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PNAS.84.16.5725

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Proceedings of the National Academy of Sciences of the United States of America

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Activation of transforming potential of the human insulin receptor gene

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B Lin

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D Dixon

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L Ellis

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L H Wang

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R A Roth

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S M Jong

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W J Rutter

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P2860

Human c-ros-1 gene homologous to the v-ros sequence of UR2 sarcoma virus encodes for a transmembrane receptorlike molecule

The c-fms proto-oncogene product is related to the receptor for the mononuclear phagocyte growth factor, CSF-1

The human insulin receptor cDNA: the structural basis for hormone-activated transmembrane signalling

Human insulin receptor and its relationship to the tyrosine kinase family of oncogenes

Human epidermal growth factor receptor cDNA sequence and aberrant expression of the amplified gene in A431 epidermoid carcinoma cells

Mutations in the cytoplasmic domain of EGF receptor affect EGF binding and receptor internalization.

Heterologous transmembrane signaling by a human insulin receptor-v-ros hybrid in Chinese hamster ovary cells.

Insulin action is blocked by a monoclonal antibody that inhibits the insulin receptor kinase

Nucleotide sequence of the feline retroviral oncogene v-fms shows unexpected homology with oncogenes encoding tyrosine-specific protein kinases.

Rous sarcoma virus variants that carry the cellular src gene instead of the viral src gene cannot transform chicken embryo fibroblasts

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5725-5729

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scholarly article

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