Expression cloning of a novel suppressor of the Lec15 and Lec35 glycosylation mutations of Chinese hamster ovary cells.
about
Human dolichol-phosphate-mannose synthase consists of three subunits, DPM1, DPM2 and DPM3Requirement of the Lec35 gene for all known classes of monosaccharide-P-dolichol-dependent glycosyltransferase reactions in mammalsDPM2 regulates biosynthesis of dolichol phosphate-mannose in mammalian cells: correct subcellular localization and stabilization of DPM1, and binding of dolichol phosphateA homologue of Saccharomyces cerevisiae Dpm1p is not sufficient for synthesis of dolichol-phosphate-mannose in mammalian cellsA mutation in the human MPDU1 gene causes congenital disorder of glycosylation type If (CDG-If)Dolichol phosphate mannose synthase (DPM1) mutations define congenital disorder of glycosylation Ie (CDG-Ie)Human and Saccharomyces cerevisiae dolichol phosphate mannose synthases represent two classes of the enzyme, but both function in Schizosaccharomyces pombeMammalian PIG-X and yeast Pbn1p are the essential components of glycosylphosphatidylinositol-mannosyltransferase I.Cystinosin, the protein defective in cystinosis, is a H(+)-driven lysosomal cystine transporterHeptahelical protein PQLC2 is a lysosomal cationic amino acid exporter underlying the action of cysteamine in cystinosis therapyThe ins(ide) and out(side) of dolichyl phosphate biosynthesis and recycling in the endoplasmic reticulumBiosynthesis of glycosylphosphatidylinositols in mammals and unicellular microbes.Large induces functional glycans in an O-mannosylation dependent manner and targets GlcNAc terminals on alpha-dystroglycanAnalysis and metabolic engineering of lipid-linked oligosaccharides in glycosylation-deficient CHO cellsUpdate and perspectives on congenital disorders of glycosylation.Congenital disorders of glycosylation: glycosylation defects in man and biological models for their study.High-throughput screening identifies aclacinomycin as a radiosensitizer of EGFR-mutant non-small cell lung cancerMannose phosphate isomerase regulates fibroblast growth factor receptor family signaling and glioma radiosensitivity.Mechanism of proton/substrate coupling in the heptahelical lysosomal transporter cystinosin.Requirement of N-glycan on GPI-anchored proteins for efficient binding of aerolysin but not Clostridium septicum alpha-toxin.Glycosylphosphatidylinositol mannosyltransferase II is the rate-limiting enzyme in glycosylphosphatidylinositol biosynthesis under limited dolichol-phosphate mannose availability.MPDU1 regulates CEACAM1 and cell adhesion in vitro and in vivo.
P2860
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P2860
Expression cloning of a novel suppressor of the Lec15 and Lec35 glycosylation mutations of Chinese hamster ovary cells.
description
1996 nî lūn-bûn
@nan
1996 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1996 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
name
Expression cloning of a novel ...... f Chinese hamster ovary cells.
@ast
Expression cloning of a novel ...... f Chinese hamster ovary cells.
@en
Expression cloning of a novel ...... f Chinese hamster ovary cells.
@nl
type
label
Expression cloning of a novel ...... f Chinese hamster ovary cells.
@ast
Expression cloning of a novel ...... f Chinese hamster ovary cells.
@en
Expression cloning of a novel ...... f Chinese hamster ovary cells.
@nl
prefLabel
Expression cloning of a novel ...... f Chinese hamster ovary cells.
@ast
Expression cloning of a novel ...... f Chinese hamster ovary cells.
@en
Expression cloning of a novel ...... f Chinese hamster ovary cells.
@nl
P2860
P356
P1476
Expression cloning of a novel ...... f Chinese hamster ovary cells.
@en
P2093
P2860
P304
13935-13938
P356
10.1074/JBC.271.24.13935
P407
P577
1996-06-01T00:00:00Z