Pyruvate sensitizes pancreatic tumors to hypoxia-activated prodrug TH-302. - sprookjes - yvandenbroek - TriplyDB

Pyruvate sensitizes pancreatic tumors to hypoxia-activated prodrug TH-302.

Pyruvate sensitizes pancreatic tumors to hypoxia-activated prodrug TH-302.

http://www.wikidata.org/entity/Q34460489

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Targeting the hypoxic fraction of tumours using hypoxia-activated prodrugs Identification of KCa3.1 Channel as a Novel Regulator of Oxidative Phosphorylation in a Subset of Pancreatic Carcinoma Cell Lines MR Imaging Biomarkers to Monitor Early Response to Hypoxia-Activated Prodrug TH-302 in Pancreatic Cancer Xenografts.Evaluation of the "steal" phenomenon on the efficacy of hypoxia activated prodrug TH-302 in pancreatic cancer Evaluation of CAIX and CAXII Expression in Breast Cancer at Varied O2 Levels: CAIX is the Superior Surrogate Imaging Biomarker of Tumor Hypoxia.Sexual dimorphism in glioma glycolysis underlies sex differences in survival Molecular Pathways: Hypoxia-Activated Prodrugs in Cancer Therapy.Hypoxia Imaging With PET Correlates With Antitumor Activity of the Hypoxia-Activated Prodrug Evofosfamide (TH-302) in Rodent Glioma Models.PDK2-mediated alternative splicing switches Bnip3 from cell death to cell survival.Anticancer efficacy of the hypoxia-activated prodrug evofosfamide is enhanced in combination with proapoptotic receptor agonists against osteosarcoma.Diagnostic assessment of osteosarcoma chemoresistance based on Virtual Clinical Trials.Identification of a pyruvate-to-lactate signature in pancreatic intraductal papillary mucinous neoplasms.Towards personalized computational oncology: from spatial models of tumour spheroids, to organoids, to tissues.Therapeutic Targeting of the Pyruvate Dehydrogenase Complex/Pyruvate Dehydrogenase Kinase (PDC/PDK) Axis in Cancer.Pulsed Electron Paramagnetic Resonance Imaging: Applications in the Studies of Tumor Physiology.Micropharmacology: An In Silico Approach for Assessing Drug Efficacy Within a Tumor Tissue.Targeting Ligand Specificity Linked to Tumor Tissue Topological Heterogeneity via Single-Cell Micro-Pharmacological Modeling.Hypoxia-activated prodrugs and redox-responsive nanocarriers

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P2860

Pyruvate sensitizes pancreatic tumors to hypoxia-activated prodrug TH-302.

http://www.wikidata.org/entity/Q34460489

description

2015 nî lūn-bûn

@nan

2015 թուականի Յունուարին հրատարակուած գիտական յօդուած

@hyw

2015 թվականի հունվարին հրատարակված գիտական հոդված

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2015年の論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年论文

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name

Pyruvate sensitizes pancreatic tumors to hypoxia-activated prodrug TH-302.

@ast

Pyruvate sensitizes pancreatic tumors to hypoxia-activated prodrug TH-302.

@en

Pyruvate sensitizes pancreatic tumors to hypoxia-activated prodrug TH-302.

@nl

type

label

Pyruvate sensitizes pancreatic tumors to hypoxia-activated prodrug TH-302.

@ast

Pyruvate sensitizes pancreatic tumors to hypoxia-activated prodrug TH-302.

@en

Pyruvate sensitizes pancreatic tumors to hypoxia-activated prodrug TH-302.

@nl

prefLabel

Pyruvate sensitizes pancreatic tumors to hypoxia-activated prodrug TH-302.

@ast

Pyruvate sensitizes pancreatic tumors to hypoxia-activated prodrug TH-302.

@en

Pyruvate sensitizes pancreatic tumors to hypoxia-activated prodrug TH-302.

@nl

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Cancer & Metabolism

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Pyruvate sensitizes pancreatic tumors to hypoxia-activated prodrug TH-302.

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Amanda F Baker

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Charles Hart

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Craig Weber

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Gary Martinez

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Heather C Cornnell

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James B Mitchell

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Jonathan W Wojtkowiak

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Katarzyna A Rejniak

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Kate M Bailey

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Keita Saito

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P2860

The SLC16 gene family-from monocarboxylate transporters (MCTs) to aromatic amino acid transporters and beyond

Hypoxia-inducible expression of tumor-associated carbonic anhydrases

Targeting hypoxia in cancer therapy

Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours

Anticancer targets in the glycolytic metabolism of tumors: a comprehensive review

Interaction between HERC1 and M2-type pyruvate kinase.

Molecular and cellular pharmacology of the hypoxia-activated prodrug TH-302.

Intracellular electric field and pH optimize protein localization and movement.

Measurement of absolute oxygen levels in cells and tissues using oxygen sensors and 2-nitroimidazole EF5.

Functional defects in the fanconi anemia pathway in pancreatic cancer cells.

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